3643 |
INSULIN RECEPTOR |
INSR |
CD220 |
HHF5 |
147670 |
6091 |
ENSG00000171105 |
OTTHUMG00000181992 |
P06213 |
INSR_HUMAN |
IR |
Insulin receptor subunit alpha |
CD_antigen=CD220 |
Insulin receptor subunit beta |
INSULIN RECEPTOR PRECURSOR (EC 2.7.1.112) (IR) (CD220 ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P06213] |
PA202 |
T85435 |
Target Main Class | Receptors |
Target Subclass | Kinase |
Transmembrane Helix Count | 1 |
Target Subclass | InsR |
Uniprot Status | Swiss-Prot |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Acc | IPR001245 |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
Interpro Name | Serine-threonine/tyrosine-protein kinase catalytic domain |
Human Readable Name | KINASE |
Target Class | Receptors |
Target Subclass | EC:2.7.10.1 |
Gene Biotype | PROTEIN_CODING |
TRANSPORTER |
KINASE |
TYROSINE KINASE |
EXTERNAL SIDE OF PLASMA MEMBRANE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
ENZYME |
TRANSCRIPTION FACTOR |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Insulin receptor inhibitor |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
agonist (activating) |
Mechanism of Interaction | Insulin receptor agonist |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | Insulin receptor inhibitor |
Direct Interaction | yes |
Notes |
inhibitor (inhibitory) |
Notes | |
Mechanism of Interaction | Insulin receptor inhibitor |
Direct Interaction | yes |
agonist (activating) |
Direct Interaction | yes |
Mechanism of Interaction | Insulin receptor agonist |
Trial Name | TPM-02/Insulin |
inhibitor (inhibitory) |
INSR | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
INSULIN RECEPTOR PRECURSOR (EC 2.7.1.112) (IR) (CD220 ANTIGEN). [SOURCE:UNIPROT/SWISSPROT;ACC:P06213] | Description |
ENSG00000171105 | Ensembl Gene Id |
INSR | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
INSR | Gene Symbol |
Target Class | Receptors |
Target Subclass | EC:2.7.10.1 |
P06213 | Uniprot Accession |
ENSG00000171105 | Ensembl Gene Id |
INSR | Gene Symbol |
Target Main Class | Receptors |
Target Subclass | Kinase |
Transmembrane Helix Count | 1 |
INSR_HUMAN | Uniprot Id |
3643 | Entrez Gene Id |
ENSG00000171105 | Ensembl Gene Id |
Uniprot Status | Swiss-Prot |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Domain |
KINASE, DRUGGABLE GENOME |
PA202 | PharmGKB ID |
INSR | TTD Gene Abbreviation |
T85435 | TTD Target ID |
ENSG00000171105 | Gene Symbol |
INSR | Ensembl Id |
DRUGGABLE GENOME |
INSR | GENE_SYMBOL |
Insulin receptor | UNIPROT |
Insulin receptor subunit alpha | UNIPROT |
IR | Gene Symbol |
3643 | Gene ID |
CD220 | dGene Synonym |
HHF5 | dGene Synonym |
KINASE, TYROSINE KINASE |
Insulin receptor | Gene Name |
P06213 | UniProt ID |
TRANSPORTER, KINASE, ENZYME, TRANSCRIPTION FACTOR |
CLINICALLY ACTIONABLE |
TYROSINE KINASE, EXTERNAL SIDE OF PLASMA MEMBRANE |
CLINICALLY ACTIONABLE |