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IDH3B Gene Record

  • Summary
  • Interactions
  • Claims
  • IDH3B 3420

    Alternate Names:

    3420
    ISOCITRATE DEHYDROGENASE 3 (NAD(+)) BETA
    IDH3B
    RP46
    604526
    5385
    ENSG00000101365
    OTTHUMG00000031699
    BE0000559
    O43837
    Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Stein et al., 1967, Diphosphopyridine nucleotide specific isocitric dehydrogenase of mammalian mitochondria. I. On the roles of pyridine nucleotide transhydrogenase and the isocitric dehydrogenases in the respiration of mitochondria of normal and neoplastic tissues., Biochemistry
    SANWAL et al., 1964, NICOTINAMIDE ADENINE DINUCLEOTIDE-SPECIFIC ISOCITRIC DEHYDROGENASE. A POSSIBLE REGULATORY PROTEIN., J. Biol. Chem.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Rose, 1966, The stereochemistry of the nicotinamide adenine dinucleotide-specific isocitric dehydrogenase reaction., J. Biol. Chem.
  • CHEMBL1161866   IDH3B

    Interaction Score: 2.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    4292141 14189899 17139284 17016423 4380379


    Sources:
    DrugBank

  • Ensembl: ENSG00000101365

    • Version: 101_38

    Alternate Names:
    IDH3B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DrugBank: BE0000559

    • Version: 5.1.7

    Alternate Names:
    IDH3B DrugBank Gene Name
    O43837 UniProt Accession
    3420 Entrez Gene Id

    Gene Info:

    Publications:
    Stein et al., 1967, Diphosphopyridine nucleotide specific isocitric dehydrogenase of mammalian mitochondria. I. On the roles of pyridine nucleotide transhydrogenase and the isocitric dehydrogenases in the respiration of mitochondria of normal and neoplastic tissues., Biochemistry
    SANWAL et al., 1964, NICOTINAMIDE ADENINE DINUCLEOTIDE-SPECIFIC ISOCITRIC DEHYDROGENASE. A POSSIBLE REGULATORY PROTEIN., J. Biol. Chem.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

  • Pharos: IDH3B

    • Version: 03-September-2020

    Alternate Names:
    Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial Gene Name
    O43837 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21