• HTR3D 200909 Druggable Genome

    Alternate Names:

    200909
    5-HYDROXYTRYPTAMINE RECEPTOR 3D
    HTR3D
    5HT3D
    610122
    24004
    ENSG00000186090
    OTTHUMG00000156858
    376
    5-HT3D
    NM_182537
    NP_872343
    Q70Z44
    5-HT3-D
    Serotonin receptor 3D
    5HT3D_HUMAN

    Gene Info:

    GuideToPharmacology Gene Category Name 5-HT<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 68
    Target Class Receptors
    Target Subclass TC:1.A.9
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Name Neurotransmitter-gated ion-channel
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Family
    Interpro Acc IPR006202
    Human Readable Name ION CHANNEL
    Uniprot Status Swiss-Prot
    Interpro Short Name Neur_chan_lig-bd
    Uniprot Evidence 1: Evidence at protein level
    Interpro Short Name Neur_channel
    Interpro Acc IPR006201
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 2.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name Pumosetrag
    Novel drug target Established target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 2.13

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 1.59

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Established target
    Trial Name dolasetron mesylate,Anzemet

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.98

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Serotonin 3 (5-HT3) receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name granisetron nasal spray
    Novel drug target Established target
    Trial Name granisetron (intranasal), TRG

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

    • Version: 101_38

    Alternate Names:
    HTR3D Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    HTR3D Gene Symbol

    Gene Info:
    Target Class Receptors
    Target Subclass TC:1.A.9

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    HTR3D Uniprot Gene Name
    5HT3D_HUMAN Uniprot Id
    Q70Z44 Uniprot Accession

    Gene Info:
    Interpro Name Neurotransmitter-gated ion-channel ligand-binding
    Interpro Name Neurotransmitter-gated ion-channel
    Interpro Type Domain

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    24004 HUGO Gene ID
    24004 HUGO Gene Symbol
    5-hydroxytryptamine receptor 3D HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name 5-HT<sub>3</sub> receptors
    GuideToPharmacology Gene Category ID 68

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: chembl_23

    Alternate Names:
    HTR3D GENE_SYMBOL
    5-hydroxytryptamine receptor 3D UNIPROT
    Serotonin receptor 3D UNIPROT

    Gene Info:

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000186090 Gene Symbol
    HTR3D Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    5-hydroxytryptamine receptor 3D Gene Name
    Q70Z44 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: