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HTR1F 3355 Druggable Genome
Alternate Names:
3355 5-HYDROXYTRYPTAMINE RECEPTOR 1F HTR1F 5-HT-1F 5-HT1F 5HT6 HTR1EL MR77 182134 5292 ENSG00000179097 OTTHUMG00000159008 P30939 5HT1F_HUMAN Serotonin receptor 1F BE0000460 5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR 1F). [SOURCE:UNIPROT/SWISSPROT;ACC:P30939] 5 5-HT<sub>1F</sub> receptor 5-HT 1F receptor T78656 NM_000866 NP_000857 Gene Info:
Transmembrane Helix Count 7 Target Subclass GPCR Target Main Class Receptors Target Subclass Rhodopsin Human Readable Name DRUGGABLE GENOME Human Readable Name G PROTEIN COUPLED RECEPTOR Interpro Short Name 7TM_GPCR_Rhodpsn Uniprot Status Swiss-Prot Interpro Type Family Uniprot Evidence 2: Evidence at transcript level Interpro Acc IPR000276 Interpro Name GPCR, rhodopsin-like, 7TM Target Class Receptors Gene Biotype PROTEIN_CODING GuideToPharmacology Gene Category Name 5-Hydroxytryptamine receptors GuideToPharmacology Gene Category ID 1 Gene Categories: Category Details
G PROTEIN COUPLED RECEPTOR DRUGGABLE GENOME Publications:
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Interaction Score: 11.36
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name lasmiditan, COL-144, LY-573144 Novel drug target Established target Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist -
Interaction Score: 4.17
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False Novel drug target Established target -
Interaction Score: 2.65
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Interaction Score: 2.52
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Trial Name zolmitriptan,Zomig Novel drug target Established target Specific Action of the Ligand Full agonist -
Interaction Score: 1.89
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Interaction Score: 1.58
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False Direct Interaction? True -
Interaction Score: 1.26
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.63
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist Direct Interaction yes -
Interaction Score: 0.63
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction yes Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist -
Interaction Score: 0.47
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Score: 0.33
Interaction Types & Directionality:
binder antagonist (inhibitory) Interaction Info:
Specific Action of the Ligand Antagonist Endogenous Drug? False -
Interaction Score: 0.33
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Score: 0.21
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Score: 0.21
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Partial agonist -
Interaction Score: 0.19
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Score: 0.17
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Antagonist -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Score: 0.16
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Score: 0.13
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Specific Action of the Ligand Antagonist Endogenous Drug? False -
Interaction Score: 0.1
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Specific Action of the Ligand Antagonist Endogenous Drug? False -
Interaction Score: 0.1
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Antagonist -
Interaction Score: 0.09
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Specific Action of the Ligand Antagonist Endogenous Drug? False -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? True Direct Interaction? False -
Interaction Score: 0.04
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Full agonist -
Interaction Score: 0.03
Interaction Types & Directionality:
antagonist (inhibitory) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Antagonist -
Interaction Score: 0.03
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False -
Interaction Types & Directionality:
agonist (activating) Interaction Info:
Specific Action of the Ligand Full agonist Endogenous Drug? False
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- Version: 101_38
Alternate Names:
HTR1F Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
-
Alternate Names:
ENSG00000179097 Ensembl Gene Id P30939 Uniprot Accession HTR1F Gene Symbol Gene Info:
Transmembrane Helix Count 7 Target Subclass GPCR Target Main Class Receptors Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000179097 Ensembl Gene Id 5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR 1F). [SOURCE:UNIPROT/SWISSPROT;ACC:P30939] Description HTR1F Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
HTR1F Gene Symbol Gene Info:
Target Class Receptors Target Subclass GPCR Target Subclass Rhodopsin Publications:
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- Version: 11-September-2012
Alternate Names:
HTR1F Uniprot Gene Name 3355 Entrez Gene Id P30939 Uniprot Accession Gene Info:
Human Readable Name G PROTEIN COUPLED RECEPTOR Human Readable Name DRUGGABLE GENOME Interpro Short Name 7TM_GPCR_Rhodpsn Gene Categories:
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
5292 HUGO Gene ID 5292 HUGO Gene Symbol 5-hydroxytryptamine receptor 1F HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name 5-Hydroxytryptamine receptors GuideToPharmacology Gene Category ID 1 Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications:
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Alternate Names:
HTR1F DrugBank Gene Name P30939 UniProt Accession 3355 Entrez Gene Id Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000179097 Gene Symbol HTR1F Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
HTR1EL GENE_SYMBOL HTR1F GENE_SYMBOL 5-hydroxytryptamine receptor 1F UNIPROT Gene Info:
Publications:
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Alternate Names:
HTR1EL GO Gene Synonym Gene Info:
Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications:
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Alternate Names:
3355 Gene ID 5-HT-1F dGene Synonym 5-HT1F dGene Synonym Gene Info:
Gene Categories:
G PROTEIN COUPLED RECEPTOR Publications:
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- Version: 2020.06.01
Alternate Names:
HTR1F TTD Gene Abbreviation T78656 TTD Target ID Gene Info:
Publications: