DGIdb - HTR1F Gene Record

HTR1F 3355 Druggable Genome

Alternate Names:

3355
5-HYDROXYTRYPTAMINE RECEPTOR 1F
HTR1F
5-HT-1F
5-HT1F
5HT6
HTR1EL
MR77
182134
5292
ENSG00000179097
OTTHUMG00000159008
P30939
5HT1F_HUMAN
Serotonin receptor 1F
5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR 1F). [SOURCE:UNIPROT/SWISSPROT;ACC:P30939]
5
5-HT<sub>1F</sub> receptor
5-HT 1F receptor
T78656
NM_000866
NP_000857

Gene Info:

Transmembrane Helix Count	7
Target Subclass	GPCR
Target Main Class	Receptors
Target Subclass	Rhodopsin
Human Readable Name	DRUGGABLE GENOME
Human Readable Name	G PROTEIN COUPLED RECEPTOR
Interpro Short Name	7TM_GPCR_Rhodpsn
Uniprot Status	Swiss-Prot
Interpro Type	Family
Uniprot Evidence	2: Evidence at transcript level
Interpro Acc	IPR000276
Interpro Name	GPCR, rhodopsin-like, 7TM
Target Class	Receptors
Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	5-Hydroxytryptamine receptors
GuideToPharmacology Gene Category ID	1

(6 More Sources)

Gene Categories: Category Details

G PROTEIN COUPLED RECEPTOR
DRUGGABLE GENOME

Publications:

Tfelt-Hansen et al., 2000, Triptans in migraine: a comparative review of pharmacology, pharmacokinetics and efficacy., Drugs
Massiou, 2001, Naratriptan., Curr Med Res Opin
Villalón et al., 2002, An introduction to migraine: from ancient treatment to functional pharmacology and antimigraine therapy., Proc. West. Pharmacol. Soc.
Chen et al., 2002, TTD: Therapeutic Target Database., Nucleic Acids Res.
Hoskin et al., 2004, The 5-hydroxytryptamine1B/1D/1F receptor agonists eletriptan and naratriptan inhibit trigeminovascular input to the nucleus tractus solitarius in the cat., Brain Res.
Villalón et al., 2003, Migraine: pathophysiology, pharmacology, treatment and future trends., Curr Vasc Pharmacol
Goadsby et al., 2003, Evidence for serotonin (5-HT)1B, 5-HT1D and 5-HT1F receptor inhibitory effects on trigeminal neurons with craniovascular input., Neuroscience
Wainscott et al., 1998, Human 5-HT1F receptor-stimulated [35S]GTPgammaS binding: correlation with inhibition of guinea pig dural plasma protein extravasation., Eur. J. Pharmacol.
Mitsikostas et al., 2002, 5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis., Cephalalgia
Mitsikostas et al., 1999, Both 5-HT1B and 5-HT1F receptors modulate c-fos expression within rat trigeminal nucleus caudalis., Eur. J. Pharmacol.
Pauwels et al., Present and future of 5-HT receptor agonists as antimigraine drugs., Clin Neuropharmacol
Janssen et al., 2004, Influence of 5-HT1 receptor agonists on feline stomach relaxation., Eur. J. Pharmacol.
Nikai et al., 2008, Profound reduction of somatic and visceral pain in mice by intrathecal administration of the anti-migraine drug, sumatriptan., Pain
Cohen et al., 2000, Contractile responses to sumatriptan and ergotamine in the rabbit saphenous vein: effect of selective 5-HT(1F) receptor agonists and PGF(2alpha)., Br. J. Pharmacol.
Razzaque et al., 1999, Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT1B- and 5-HT1F-receptor activation., Br J Clin Pharmacol
Bigal et al., 2003, Ergotamine and dihydroergotamine: a review., Curr Pain Headache Rep
Reuter U et al., 2015, The pharmacological profile and clinical prospects of the oral 5-HT1F receptor agonist lasmiditan in the acute treatment of migraine., Ther Adv Neurol Disord
Reuter et al., 2004, Effects of chronic sumatriptan and zolmitriptan treatment on 5-HT receptor expression and function in rats., Cephalalgia
Bhalla et al., 2002, Molecular cloning and expression of the porcine trigeminal ganglion cDNA encoding a 5-ht(1F) receptor., Eur. J. Pharmacol.
Martin, 1997, Pre-clinical pharmacology of zolmitriptan (Zomig; formerly 311C90), a centrally and peripherally acting 5HT1B/1D agonist for migraine., Cephalalgia
Rubio-Beltrán E et al., 2018, Is selective 5-HT<sub>1F</sub> receptor agonism an entity apart from that of the triptans in antimigraine therapy?, Pharmacol Ther
Adham et al., 1993, Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase., Proc. Natl. Acad. Sci. U.S.A.
Jähnichen et al., 2004, Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery., Naunyn Schmiedebergs Arch. Pharmacol.
Napier et al., 1999, Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors., Eur. J. Pharmacol.

LASMIDITAN HTR1F

Interaction Score: 11.0

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name lasmiditan, COL-144, LY-573144

Novel drug target Established target

Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

PMIDs:
25584073

Sources:
TdgClinicalTrial ChemblInteractions GuideToPharmacology TTD
NARATRIPTAN HTR1F

Interaction Score: 4.4

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Novel drug target Established target

PMIDs:
11152011 12463278 12434581 11752352 14725972 15320857 14614913

Sources:
TdgClinicalTrial TEND GuideToPharmacology
ZOLMITRIPTAN HTR1F

Interaction Score: 4.03

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name zolmitriptan,Zomig

Novel drug target Established target

Specific Action of the Ligand Full agonist

PMIDs:
12434581 9718276 11752352 15096229 15320857 11834243 9399012 29352859

Sources:
TdgClinicalTrial TEND GuideToPharmacology
RIZATRIPTAN HTR1F

Interaction Score: 2.64

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
15320857 9718276 14614913 11752352 12434581

Sources:
GuideToPharmacology
CHEMBL101690 HTR1F

Interaction Score: 2.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
ELETRIPTAN HTR1F

Interaction Score: 1.47

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? True

PMIDs:
15185063 11834243 10193663

Sources:
GuideToPharmacology
SUMATRIPTAN HTR1F

Interaction Score: 1.34

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? False

PMIDs:
12110114 10225363 10367177 15178373 18723285 11752352 11015308 10073743

Sources:
TdgClinicalTrial TEND GuideToPharmacology
ELETRIPTAN HYDROBROMIDE HTR1F

Interaction Score: 0.73

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions
ALMOTRIPTAN MALATE HTR1F

Interaction Score: 0.73

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

PMIDs:
None found

Sources:
ChemblInteractions
CHEMBL1256797 HTR1F

Interaction Score: 0.55

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology
ERGOTAMINE HTR1F

Interaction Score: 0.49

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
12525272

Sources:
GuideToPharmacology
5-MEO-DMT HTR1F

Interaction Score: 0.44

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
DIHYDROERGOTAMINE HTR1F

Interaction Score: 0.27

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
METHYSERGIDE HTR1F

Interaction Score: 0.26

Interaction Types & Directionality:

binder

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
8380639

Sources:
GuideToPharmacology
DONITRIPTAN HTR1F

Interaction Score: 0.24

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
BRL-15,572 HTR1F

Interaction Score: 0.24

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Partial agonist

PMIDs:
None found

Sources:
GuideToPharmacology
METHYLERGONOVINE HTR1F

Interaction Score: 0.2

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology
8-OH-DPAT HTR1F

Interaction Score: 0.2

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology
TRYPTAMINE HTR1F

Interaction Score: 0.18

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology
YOHIMBINE HTR1F

Interaction Score: 0.16

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
XANOMELINE HTR1F

Interaction Score: 0.15

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
METERGOLINE HTR1F

Interaction Score: 0.12

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology
SEROTONIN HTR1F

Interaction Score: 0.12

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? True

Direct Interaction? False

PMIDs:
None found

Sources:
GuideToPharmacology
SERTINDOLE HTR1F

Interaction Score: 0.12

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
METITEPINE HTR1F

Interaction Score: 0.1

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
QUETIAPINE HTR1F

Interaction Score: 0.07

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology
RISPERIDONE HTR1F

Interaction Score: 0.03

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology
OLANZAPINE HTR1F

Interaction Score: 0.03

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology
CLOZAPINE HTR1F

Interaction Score: 0.03

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Ensembl: ENSG00000179097
- Version: 101_38
Alternate Names:

HTR1F Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TEND: P30939
- Version: 01-August-2011
Alternate Names:

ENSG00000179097 Ensembl Gene Id

P30939 Uniprot Accession

HTR1F Gene Symbol

Gene Info:

Transmembrane Helix Count 7

Target Subclass GPCR

Target Main Class Receptors

Publications:
RussLampel: ENSG00000179097
- Version: 26-July-2011
Alternate Names:

ENSG00000179097 Ensembl Gene Id

5-HYDROXYTRYPTAMINE 1F RECEPTOR (5-HT-1F) (SEROTONIN RECEPTOR 1F). [SOURCE:UNIPROT/SWISSPROT;ACC:P30939] Description

HTR1F Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
TdgClinicalTrial: P30939
- Version: January-2014
Alternate Names:

HTR1F Gene Symbol

Gene Info:

Target Class Receptors

Target Subclass GPCR

Target Subclass Rhodopsin

Publications:
HopkinsGroom: P30939
- Version: 11-September-2012
Alternate Names:

HTR1F Uniprot Gene Name

3355 Entrez Gene Id

P30939 Uniprot Accession

Gene Info:

Human Readable Name G PROTEIN COUPLED RECEPTOR

Human Readable Name DRUGGABLE GENOME

Interpro Short Name 7TM_GPCR_Rhodpsn

Gene Categories:

G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

Publications:
GuideToPharmacology: 3355
- Version: 29-September-2020
Alternate Names:

5292 HUGO Gene ID

5292 HUGO Gene Symbol

5-hydroxytryptamine receptor 1F HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name 5-Hydroxytryptamine receptors

GuideToPharmacology Gene Category ID 1

Gene Categories:

G PROTEIN COUPLED RECEPTOR

Publications:
HingoraniCasas: ENSG00000179097
- Version: 31-May-2017
Alternate Names:

ENSG00000179097 Gene Symbol

HTR1F Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
ChemblInteractions: HTR1EL
- Version: chembl_23
Alternate Names:

HTR1EL GENE_SYMBOL

HTR1F GENE_SYMBOL

5-hydroxytryptamine receptor 1F UNIPROT

Gene Info:

Publications:
dGene: HTR1F
- Version: 27-Jun-2013
Alternate Names:

3355 Gene ID

5-HT-1F dGene Synonym

5-HT1F dGene Synonym

Gene Info:

Gene Categories:

G PROTEIN COUPLED RECEPTOR

Publications:
TTD: 5-HT 1F receptor
- Version: 2020.06.01
Alternate Names:

HTR1F TTD Gene Abbreviation

T78656 TTD Target ID

Gene Info:

Publications:

Trial Name	lasmiditan, COL-144, LY-573144
Novel drug target	Established target
Mechanism of Interaction	Serotonin 1f (5-HT1f) receptor agonist

Specific Action of the Ligand	Full agonist
Endogenous Drug?	False
Novel drug target	Established target

Trial Name	zolmitriptan,Zomig
Novel drug target	Established target
Specific Action of the Ligand	Full agonist

Mechanism of Interaction	Serotonin 1f (5-HT1f) receptor agonist
Direct Interaction	yes

Direct Interaction?	False
Endogenous Drug?	False
Specific Action of the Ligand	Full agonist

Specific Action of the Ligand	Antagonist
Endogenous Drug?	False

ENSG00000179097	Ensembl Gene Id
P30939	Uniprot Accession
HTR1F	Gene Symbol

HTR1F	Uniprot Gene Name
3355	Entrez Gene Id
P30939	Uniprot Accession

5292	HUGO Gene ID
5292	HUGO Gene Symbol
5-hydroxytryptamine receptor 1F	HUGO Gene Name

HTR1EL	GENE_SYMBOL
HTR1F	GENE_SYMBOL
5-hydroxytryptamine receptor 1F	UNIPROT

binder
antagonist (inhibitory)

HTR1F Gene Record

HTR1F 3355 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name lasmiditan, COL-144, LY-573144 Novel drug target Established target Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

PMIDs: 25584073

Sources: TdgClinicalTrial ChemblInteractions GuideToPharmacology TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False Novel drug target Established target

PMIDs: 11152011 12463278 12434581 11752352 14725972 15320857 14614913

Sources: TdgClinicalTrial TEND GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Trial Name zolmitriptan,Zomig Novel drug target Established target Specific Action of the Ligand Full agonist

PMIDs: 12434581 9718276 11752352 15096229 15320857 11834243 9399012 29352859

Sources: TdgClinicalTrial TEND GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: 15320857 9718276 14614913 11752352 12434581

Sources: GuideToPharmacology

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: TTD

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False Direct Interaction? True

PMIDs: 15185063 11834243 10193663

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False Direct Interaction? False

PMIDs: 12110114 10225363 10367177 15178373 18723285 11752352 11015308 10073743

Sources: TdgClinicalTrial TEND GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist Direct Interaction yes

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction yes Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: agonist (activating)

Interaction Info: Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Full agonist

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Endogenous Drug? False Specific Action of the Ligand Full agonist

PMIDs: 12525272

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: binder antagonist (inhibitory)

Interaction Info: Specific Action of the Ligand Antagonist Endogenous Drug? False

PMIDs: 8380639

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Specific Action of the Ligand Full agonist Endogenous Drug? False

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Endogenous Drug? False Specific Action of the Ligand Partial agonist

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: antagonist (inhibitory)

Interaction Info: Endogenous Drug? False Specific Action of the Ligand Antagonist

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Endogenous Drug? False Specific Action of the Ligand Full agonist

PMIDs: None found

Sources: GuideToPharmacology

Interaction Types & Directionality: agonist (activating)

Interaction Info: Endogenous Drug? False Specific Action of the Ligand Full agonist

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name lasmiditan, COL-144, LY-573144

Novel drug target Established target

Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

PMIDs:
25584073

Sources:
TdgClinicalTrial ChemblInteractions GuideToPharmacology TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Novel drug target Established target

PMIDs:
11152011 12463278 12434581 11752352 14725972 15320857 14614913

Sources:
TdgClinicalTrial TEND GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Trial Name zolmitriptan,Zomig

Novel drug target Established target

Specific Action of the Ligand Full agonist

PMIDs:
12434581 9718276 11752352 15096229 15320857 11834243 9399012 29352859

Sources:
TdgClinicalTrial TEND GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
15320857 9718276 14614913 11752352 12434581

Sources:
GuideToPharmacology

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
TTD

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? True

PMIDs:
15185063 11834243 10193663

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

Direct Interaction? False

PMIDs:
12110114 10225363 10367177 15178373 18723285 11752352 11015308 10073743

Sources:
TdgClinicalTrial TEND GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Serotonin 1f (5-HT1f) receptor agonist

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Direct Interaction? False

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
12525272

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

binder

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
8380639

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Specific Action of the Ligand Full agonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Partial agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Antagonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

Endogenous Drug? False

Specific Action of the Ligand Full agonist

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

antagonist (inhibitory)

Interaction Info:

Specific Action of the Ligand Antagonist

Endogenous Drug? False

PMIDs:
None found

Sources:
GuideToPharmacology

Interaction Types & Directionality:

agonist (activating)