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HSP90AA1 Gene Record

  • Summary
  • Interactions
  • Claims
  • HSP90AA1 3320 Druggable GenomeClinically Actionable

    Alternate Names:

    3320
    HEAT SHOCK PROTEIN 90 ALPHA FAMILY CLASS A MEMBER 1
    HSP90AA1
    EL52
    HEL-S-65p
    HSP86
    HSP89A
    HSP90A
    HSP90N
    HSPC1
    HSPCA
    HSPCAL1
    HSPCAL4
    HSPN
    Hsp103
    Hsp89
    Hsp90
    LAP-2
    LAP2
    140571
    5253
    ENSG00000080824
    OTTHUMG00000171752
    Lipopolysaccharide-associated protein 2
    LPS-associated protein 2
    HSP 86
    Heat shock protein HSP 90-alpha
    Renal carcinoma antigen NY-REN-38
    Heat shock 86 kDa
    BE0001120
    P07900
    HS90A_HUMAN
    2905
    HEAT SHOCK PROTEIN HSP 90-ALPHA (HSP 86). [SOURCE:UNIPROT/SWISSPROT;ACC:P07900]
    Heat shock protein 90 alpha
    T18477
    NP_005339
    NM_005348

    Gene Info:

    CancerCommons Reported Gene Name HSP90
    Interpro Short Name ATPase-like_ATP-bd
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR003594
    Uniprot Status Swiss-Prot
    Interpro Name ATPase-like, ATP-binding domain
    Target Class Miscellaneous
    Target Subclass HSP90-like_chaperon
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Heat shock proteins
    GuideToPharmacology Gene Category ID 784
    (14 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    TRANSCRIPTION FACTOR

    Publications:

    Shaaban KA et al., 2013, Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15., J Nat Prod
    Dal Piaz F et al., 2013, A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors., J Med Chem
    Li Z et al., 2014, Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors., Eur J Med Chem
    Lauria A et al., 2013, Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening., J Med Chem
    Ramsey DM et al., 2012, An Hsp90 modulator that exhibits a unique mechanistic profile., Bioorg Med Chem Lett
    O'Boyle NM et al., 2011, Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90., Bioorg Med Chem
    Kunicki JB et al., 2011, Synthesis and evaluation of biotinylated sansalvamide A analogs and their modulation of Hsp90., Bioorg Med Chem Lett
    Hall JA et al., 2015, Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery., J Nat Prod
    Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem
    Degterev A et al., 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins., Nat Chem Biol
    Hadden MK et al., 2007, Derrubone, an inhibitor of the Hsp90 protein folding machinery., J Nat Prod
    Zhao H et al., 2011, Identification and initial SAR of silybin: an Hsp90 inhibitor., Bioorg Med Chem Lett
    Kusuma BR et al., 2011, Targeting the heat shock protein 90 dimer with dimeric inhibitors., J Med Chem
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Okada et al., 2003, Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox., Biochem. J.
    Nishikawa et al., 2008, Heat shock protein derivatives for delivery of antigens to antigen presenting cells., Int J Pharm
    Chen D et al., 2014, Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors., Eur J Med Chem
    Turbyville TJ et al., 2006, Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desert., J Nat Prod
    Miura T et al., 2011, Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design., Bioorg Med Chem Lett
    Schnaider et al., 2000, The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation., Cell Stress Chaperones
    Münster et al., 2001, Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells., Cancer Res.
    Yang et al., 2001, Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin., Cancer Res.
    Neckers et al., 1999, Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity., Invest New Drugs
    Srethapakdi et al., 2000, Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest., Cancer Res.
    Wang M et al., 2006, Radanamycin, a macrocyclic chimera of radicicol and geldanamycin., Bioorg Med Chem Lett
    Davenport J et al., 2011, Gambogic acid, a natural product inhibitor of Hsp90., J Nat Prod
    Wang RE et al., 2011, Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins., Bioorg Med Chem
    Smith SD et al., 2004, Using immobilized metal affinity chromatography, two-dimensional electrophoresis and mass spectrometry to identify hepatocellular proteins with copper-binding ability., J Proteome Res
  • CHEMBL178130   HSP90AA1

    Interaction Score: 1.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • CHEMBL360563   HSP90AA1

    Interaction Score: 1.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • CHEMBL538937   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL470365   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL549340   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL404630   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL252124   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL324951   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL200255   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL326564   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL207701   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL563168   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL112953   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL563327   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL200469   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL1234416   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL380888   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL112834   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL109822   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL208239   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL554496   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL361078   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL326082   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL112896   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL113194   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL398346   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL410448   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL326651   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL326523   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL513225   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL109612   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL486921   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • RIFABUTIN   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    other/unknown

    Interaction Info:

    PMIDs:
    10701840 11306472 11358819 10759403 10919672


    Sources:
    DrugBank

  • CHEMBL1834096   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21875802


    Sources:
    DTC

  • ARGENTEOSIDE A   HSP90AA1

    Interaction Score: 0.64

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23362862


    Sources:
    DTC

  • CHEMBL553939   HSP90AA1

    Interaction Score: 0.48

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name SNX-5422
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial TTD DrugBank

  • ALVESPIMYCIN   HSP90AA1

    Interaction Score: 0.48

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name alvespimycin hydrochloride, KOS-1022 (DMAG), NSC-707545
    Specific Action of the Ligand Inhibition

    PMIDs:
    10592235 17139284 17016423


    Sources:
    TdgClinicalTrial DrugBank GuideToPharmacology

  • CHEMBL113690   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL383189   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • TOTAROL   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RADANAMYCIN   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16464590


    Sources:
    DTC

  • TERCONAZOLE   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL2022241   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25756299


    Sources:
    DTC

  • MONOCILLIN I   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16499313


    Sources:
    DTC

  • CUCURBITACIN D   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25756299


    Sources:
    DTC

  • CHEMBL192264   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21764310


    Sources:
    DTC

  • DESACETYL SALANNIN   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • KW-2478   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • EFUNGUMAB   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • CHEMBL463701   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BIIB021   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    TTD GuideToPharmacology

  • TOXYLOXANTHONE C   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HERBIMYCIN   HSP90AA1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23947794


    Sources:
    DTC

  • GELDANAMYCIN   HSP90AA1

    Interaction Score: 0.28

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25756299 25277067 21129982 18408713 18020309 21273068 21861487 23947794 17139284 23859777 17016423


    Sources:
    DTC DrugBank

  • TANESPIMYCIN   HSP90AA1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name CNF1010
    Mechanism of Interaction Heat shock protein HSP90 inhibitor

    PMIDs:
    25277067 23520985 22480433 21920765 21764310


    Sources:
    DTC TdgClinicalTrial TTD DrugBank MyCancerGenome ChemblInteractions

  • LUMINESPIB   HSP90AA1

    Interaction Score: 0.24

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25313505


    Sources:
    DTC TTD

  • RETASPIMYCIN HYDROCHLORIDE   HSP90AA1

    Interaction Score: 0.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Trial Name IPI-504
    Novel drug target Novel Target
    Mechanism of Interaction Heat shock protein HSP90 inhibitor

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial ChemblInteractions

  • RETASPIMYCIN   HSP90AA1

    Interaction Score: 0.21

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name IPI-493, oral retaspimycin

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial MyCancerGenome

  • NOVOBIOCIN   HSP90AA1

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21129982 23859777


    Sources:
    DTC

  • CHEMBL1688556   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL534423   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ZEARALANONE   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BUTOCONAZOLE NITRATE   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CELASTROL   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25756299


    Sources:
    DTC

  • NEDOCROMIL   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12803546 17980980


    Sources:
    DrugBank

  • XL-888   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Novel drug target Novel Target
    Trial Name XL888
    Reported Cancer Type Melanoma

    PMIDs:
    None found


    Sources:
    CancerCommons TdgClinicalTrial

  • CHEMBL1385558   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TRIADIMENOL   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL588804   HSP90AA1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GANETESPIB   HSP90AA1

    Interaction Score: 0.14

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Heat shock protein HSP90 inhibitor
    Direct Interaction yes
    Trial Name STA-9090

    PMIDs:
    None found


    Sources:
    CancerCommons TdgClinicalTrial MyCancerGenome ChemblInteractions

  • OLEOYLETHANOLAMIDE   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RADICICOL   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16499313


    Sources:
    DTC

  • CHEMBL1256761   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ONALESPIB   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Reported Cancer Type Lung

    PMIDs:
    None found


    Sources:
    CancerCommons

  • HALOFANTRINE HYDROCHLORIDE   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DERRUBONE   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18020309


    Sources:
    DTC

  • SULCONAZOLE NITRATE   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL548540   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GEDUNIN   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25756299


    Sources:
    DTC

  • CHEMBL601768   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL530499   HSP90AA1

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL399530   HSP90AA1

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CHEMBL547285   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL585827   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1439833   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL591876   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL590184   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL582983   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL602363   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GERONTOXANTHONE I   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PROPICONAZOLE   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL591361   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL582099   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL591363   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL592600   HSP90AA1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GAMBOGIC ACID   HSP90AA1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21486005


    Sources:
    DTC

  • CHEMBL365617   HSP90AA1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • CICLOPIROX OLAMINE   HSP90AA1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MICONAZOLE NITRATE   HSP90AA1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BROXYQUINOLINE   HSP90AA1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SERTACONAZOLE NITRATE   HSP90AA1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1098875   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL565893   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1306556   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SILIBININ   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21273068


    Sources:
    DTC

  • METHYLBENZETHONIUM CHLORIDE   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL548615   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TRICLABENDAZOLE   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL590927   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1546228   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1287983   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL600694   HSP90AA1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • POLAPREZINC   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DrugBank

  • ZERANOL   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL260342   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL591137   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL473721   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1466186   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TERPYRIDINE   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL599098   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • POMIFERIN   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • IODOQUINOL   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THONZONIUM BROMIDE   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL599255   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FLUCONAZOLE   HSP90AA1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOXYQUIN   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TRICLOSAN   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL428064   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL538798   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHLOROXINE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SCLEROTIORIN   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL578944   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ECONAZOLE NITRATE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PYRITHIONE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL591126   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ITRACONAZOLE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1224755   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • BIFONAZOLE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • KEPONE   HSP90AA1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ZEARALENONE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL533226   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CETYLPYRIDINIUM BROMIDE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NANAOMYCIN   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYCLOHEXIMIDE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NITROXOLINE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL528694   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1567571   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DIACEREIN   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL523200   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TETRACYCLINE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALEXIDINE HYDROCHLORIDE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLIOQUINOL   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL2095095   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AMLEXANOX   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    TTD

  • DICHLOROPHEN   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FENTICLOR   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL53898   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CALCIMYCIN   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MICONAZOLE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CALMIDAZOLIUM CHLORIDE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PHENANTHROLINE   HSP90AA1

    Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THIRAM   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RHEIN   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THIMEROSAL   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • KETOCONAZOLE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL578512   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DAUNORUBICIN HYDROCHLORIDE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOXORUBICIN HYDROCHLORIDE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL505670   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • NORDIHYDROGUAIARETIC ACID   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CLOTRIMAZOLE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • WORTMANNIN   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DISULFIRAM   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • HEXACHLOROPHENE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • QUERCETIN   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    21798748


    Sources:
    DrugBank

  • DIPYRIDAMOLE   HSP90AA1

    Interaction Score: 0.01

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • COPPER   HSP90AA1

    Interaction Score: 0.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15359738


    Sources:
    DrugBank

  • Ensembl: ENSG00000080824

    • Version: 101_38

    Alternate Names:
    HSP90AA1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P07900

    • Version: 11-September-2012

    Alternate Names:
    3320 Entrez Gene Id
    HSP90AA1 Uniprot Gene Name
    HS90A_HUMAN Uniprot Id

    Gene Info:
    Interpro Short Name ATPase-like_ATP-bd
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000080824

    • Version: 26-July-2011

    Alternate Names:
    ENSG00000080824 Ensembl Gene Id
    HSPCA Display Id
    HEAT SHOCK PROTEIN HSP 90-ALPHA (HSP 86). [SOURCE:UNIPROT/SWISSPROT;ACC:P07900] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TdgClinicalTrial: P07900

    • Version: January-2014

    Alternate Names:
    HSP90AA1 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass HSP90-like_chaperon

    Publications:

  • CancerCommons: HSP90AA1

    • Version: 25-July-2013

    Alternate Names:
    3320 Entrez Gene ID

    Gene Info:
    CancerCommons Reported Gene Name HSP90

    Publications:

  • GuideToPharmacology: 3320

    • Version: 29-September-2020

    Alternate Names:
    5253 HUGO Gene ID
    5253 HUGO Gene Symbol
    heat shock protein 90 alpha family class A member 1 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Heat shock proteins
    GuideToPharmacology Gene Category ID 784

    Publications:

  • DrugBank: BE0001120

    • Version: 5.1.7

    Alternate Names:
    HSP90AA1 DrugBank Gene Name
    P07900 UniProt Accession
    3320 Entrez Gene Id

    Gene Info:

    Publications:
    Schnaider et al., 2000, The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation., Cell Stress Chaperones
    Münster et al., 2001, Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells., Cancer Res.
    Yang et al., 2001, Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin., Cancer Res.

  • DTC: HSP90AA1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Hall JA et al., 2015, Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery., J Nat Prod
    Li Z et al., 2014, Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors., Eur J Med Chem
    Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

  • MyCancerGenome: HSP90AA1

    • Version: 20-Jun-2017

    Alternate Names:
    3320 Entrez Gene Id
    HSP90AA1 MyCancerGenome Gene Symbol
    HSP90 MyCancerGenome Reported Gene Name

    Gene Info:

    Publications:

  • HingoraniCasas: ENSG00000080824

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000080824 Gene Symbol
    HSP90AA1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: HSP90A

    • Version: chembl_23

    Alternate Names:
    HSPC1 GENE_SYMBOL
    HSPCA GENE_SYMBOL
    HSP90AA1 GENE_SYMBOL

    Gene Info:

    Publications:

  • Pharos: HSP90AA1

    • Version: 03-September-2020

    Alternate Names:
    Heat shock protein HSP 90-alpha Gene Name
    P07900 UniProt ID

    Gene Info:

    Gene Categories:
    TRANSCRIPTION FACTOR

    Publications:

  • GO: HSP90AA1

    • Version: 05-September-2020

    Alternate Names:
    HSP90A GO Gene Synonym
    HSPC1 GO Gene Synonym
    HSPCA GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

  • Tempus: HSP90AA1

    • Version: 11-November-2018

    Alternate Names:
    HSP90AA1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • TTD: Heat shock protein 90 alpha

    • Version: 2020.06.01

    Alternate Names:
    HSP90A TTD Gene Abbreviation
    T18477 TTD Target ID

    Gene Info:

    Publications:

  • MyCancerGenomeClinicalTrial: HSP90AA1

    • Version: 30-February-2014

    Alternate Names:

    Gene Info:

    Publications:

  • FoundationOneGenes: HSP90AA1

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: HSP90AA1

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

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A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21