DGIdb - HSP90AA1 Gene Record

HSP90AA1 3320 Druggable GenomeClinically Actionable

Alternate Names:

3320
HEAT SHOCK PROTEIN 90 ALPHA FAMILY CLASS A MEMBER 1
HSP90AA1
EL52
HEL-S-65p
HSP86
HSP89A
HSP90A
HSP90N
HSPC1
HSPCA
HSPCAL1
HSPCAL4
HSPN
Hsp103
Hsp89
Hsp90
LAP-2
LAP2
140571
5253
ENSG00000080824
OTTHUMG00000171752
Lipopolysaccharide-associated protein 2
LPS-associated protein 2
HSP 86
Heat shock protein HSP 90-alpha
Renal carcinoma antigen NY-REN-38
Heat shock 86 kDa
BE0001120
P07900
HS90A_HUMAN
2905
HEAT SHOCK PROTEIN HSP 90-ALPHA (HSP 86). [SOURCE:UNIPROT/SWISSPROT;ACC:P07900]
Heat shock protein 90 alpha
T18477
NP_005339
NM_005348

Gene Info:

CancerCommons Reported Gene Name	HSP90
Interpro Short Name	ATPase-like_ATP-bd
Uniprot Evidence	1: Evidence at protein level
Interpro Type	Domain
Human Readable Name	DRUGGABLE GENOME
Interpro Acc	IPR003594
Uniprot Status	Swiss-Prot
Interpro Name	ATPase-like, ATP-binding domain
Target Class	Miscellaneous
Target Subclass	HSP90-like_chaperon
Gene Biotype	PROTEIN_CODING
GuideToPharmacology Gene Category Name	Heat shock proteins
GuideToPharmacology Gene Category ID	784

(14 More Sources)

Gene Categories: Category Details

CELL SURFACE
DRUGGABLE GENOME
CLINICALLY ACTIONABLE
TRANSCRIPTION FACTOR

Publications:

Shaaban KA et al., 2013, Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15., J Nat Prod
Dal Piaz F et al., 2013, A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors., J Med Chem
Li Z et al., 2014, Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors., Eur J Med Chem
Lauria A et al., 2013, Synthesis and biological activities of a new class of heat shock protein 90 inhibitors, designed by energy-based pharmacophore virtual screening., J Med Chem
Ramsey DM et al., 2012, An Hsp90 modulator that exhibits a unique mechanistic profile., Bioorg Med Chem Lett
O'Boyle NM et al., 2011, Lead identification of β-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90., Bioorg Med Chem
Kunicki JB et al., 2011, Synthesis and evaluation of biotinylated sansalvamide A analogs and their modulation of Hsp90., Bioorg Med Chem Lett
Hall JA et al., 2015, Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery., J Nat Prod
Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem
Degterev A et al., 2008, Identification of RIP1 kinase as a specific cellular target of necrostatins., Nat Chem Biol
Hadden MK et al., 2007, Derrubone, an inhibitor of the Hsp90 protein folding machinery., J Nat Prod
Zhao H et al., 2011, Identification and initial SAR of silybin: an Hsp90 inhibitor., Bioorg Med Chem Lett
Kusuma BR et al., 2011, Targeting the heat shock protein 90 dimer with dimeric inhibitors., J Med Chem
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Gunaherath GM et al., 2013, Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors., Bioorg Med Chem
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Okada et al., 2003, Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox., Biochem. J.
Nishikawa et al., 2008, Heat shock protein derivatives for delivery of antigens to antigen presenting cells., Int J Pharm
Chen D et al., 2014, Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors., Eur J Med Chem
Turbyville TJ et al., 2006, Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desert., J Nat Prod
Miura T et al., 2011, Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design., Bioorg Med Chem Lett
Schnaider et al., 2000, The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation., Cell Stress Chaperones
Münster et al., 2001, Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells., Cancer Res.
Yang et al., 2001, Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin., Cancer Res.
Neckers et al., 1999, Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity., Invest New Drugs
Srethapakdi et al., 2000, Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest., Cancer Res.
Wang M et al., 2006, Radanamycin, a macrocyclic chimera of radicicol and geldanamycin., Bioorg Med Chem Lett
Davenport J et al., 2011, Gambogic acid, a natural product inhibitor of Hsp90., J Nat Prod
Wang RE et al., 2011, Biotinylated quercetin as an intrinsic photoaffinity proteomics probe for the identification of quercetin target proteins., Bioorg Med Chem
Smith SD et al., 2004, Using immobilized metal affinity chromatography, two-dimensional electrophoresis and mass spectrometry to identify hepatocellular proteins with copper-binding ability., J Proteome Res

CHEMBL178130 HSP90AA1

Interaction Score: 1.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL360563 HSP90AA1

Interaction Score: 1.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL538937 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL470365 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL549340 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL404630 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL252124 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL324951 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL200255 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL326564 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL207701 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL563168 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL112953 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL563327 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL200469 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL1234416 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL380888 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL112834 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL109822 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL208239 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL554496 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL361078 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL326082 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL112896 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL113194 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL398346 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL410448 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL326651 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL326523 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL513225 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL109612 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL486921 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
RIFABUTIN HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

other/unknown

Interaction Info:

PMIDs:
10701840 11306472 11358819 10759403 10919672

Sources:
DrugBank
CHEMBL1834096 HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21875802

Sources:
DTC
ARGENTEOSIDE A HSP90AA1

Interaction Score: 0.64

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23362862

Sources:
DTC
CHEMBL553939 HSP90AA1

Interaction Score: 0.48

Interaction Types & Directionality:

n/a

Interaction Info:

Trial Name SNX-5422

Novel drug target Novel Target

PMIDs:
None found

Sources:
TdgClinicalTrial TTD DrugBank
ALVESPIMYCIN HSP90AA1

Interaction Score: 0.48

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Novel Target

Trial Name alvespimycin hydrochloride, KOS-1022 (DMAG), NSC-707545

Specific Action of the Ligand Inhibition

PMIDs:
10592235 17139284 17016423

Sources:
TdgClinicalTrial DrugBank GuideToPharmacology
CHEMBL113690 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL383189 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
TOTAROL HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RADANAMYCIN HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16464590

Sources:
DTC
TERCONAZOLE HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL2022241 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25756299

Sources:
DTC
MONOCILLIN I HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16499313

Sources:
DTC
CUCURBITACIN D HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25756299

Sources:
DTC
CHEMBL192264 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21764310

Sources:
DTC
DESACETYL SALANNIN HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KW-2478 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
EFUNGUMAB HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
CHEMBL463701 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BIIB021 HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Specific Action of the Ligand Inhibition

Endogenous Drug? False

Direct Interaction? False

PMIDs:
None found

Sources:
TTD GuideToPharmacology
TOXYLOXANTHONE C HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HERBIMYCIN HSP90AA1

Interaction Score: 0.32

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23947794

Sources:
DTC
GELDANAMYCIN HSP90AA1

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25756299 25277067 21129982 18408713 18020309 21273068 21861487 23947794 17139284 23859777 17016423

Sources:
DTC DrugBank
TANESPIMYCIN HSP90AA1

Interaction Score: 0.27

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Novel Target

Trial Name CNF1010

Mechanism of Interaction Heat shock protein HSP90 inhibitor

PMIDs:
25277067 23520985 22480433 21920765 21764310

Sources:
DTC TdgClinicalTrial TTD DrugBank MyCancerGenome ChemblInteractions
LUMINESPIB HSP90AA1

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25313505

Sources:
DTC TTD
RETASPIMYCIN HYDROCHLORIDE HSP90AA1

Interaction Score: 0.21

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Trial Name IPI-504

Novel drug target Novel Target

Mechanism of Interaction Heat shock protein HSP90 inhibitor

PMIDs:
None found

Sources:
TdgClinicalTrial ChemblInteractions
RETASPIMYCIN HSP90AA1

Interaction Score: 0.21

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Novel Target

Trial Name IPI-493, oral retaspimycin

PMIDs:
None found

Sources:
TdgClinicalTrial MyCancerGenome
NOVOBIOCIN HSP90AA1

Interaction Score: 0.19

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21129982 23859777

Sources:
DTC
CHEMBL1688556 HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL534423 HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ZEARALANONE HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BUTOCONAZOLE NITRATE HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CELASTROL HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25756299

Sources:
DTC
NEDOCROMIL HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12803546 17980980

Sources:
DrugBank
XL-888 HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Novel drug target Novel Target

Trial Name XL888

Reported Cancer Type Melanoma

PMIDs:
None found

Sources:
CancerCommons TdgClinicalTrial
CHEMBL1385558 HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRIADIMENOL HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL588804 HSP90AA1

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GANETESPIB HSP90AA1

Interaction Score: 0.14

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Heat shock protein HSP90 inhibitor

Direct Interaction yes

Trial Name STA-9090

PMIDs:
None found

Sources:
CancerCommons TdgClinicalTrial MyCancerGenome ChemblInteractions
OLEOYLETHANOLAMIDE HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RADICICOL HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16499313

Sources:
DTC
CHEMBL1256761 HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ONALESPIB HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Reported Cancer Type Lung

PMIDs:
None found

Sources:
CancerCommons
HALOFANTRINE HYDROCHLORIDE HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DERRUBONE HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18020309

Sources:
DTC
SULCONAZOLE NITRATE HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL548540 HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GEDUNIN HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
25756299

Sources:
DTC
CHEMBL601768 HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL530499 HSP90AA1

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL399530 HSP90AA1

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL547285 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL585827 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1439833 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL591876 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL590184 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL582983 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL602363 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GERONTOXANTHONE I HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PROPICONAZOLE HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL591361 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL582099 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL591363 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL592600 HSP90AA1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GAMBOGIC ACID HSP90AA1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21486005

Sources:
DTC
CHEMBL365617 HSP90AA1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CICLOPIROX OLAMINE HSP90AA1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE NITRATE HSP90AA1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BROXYQUINOLINE HSP90AA1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SERTACONAZOLE NITRATE HSP90AA1

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1098875 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL565893 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1306556 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SILIBININ HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21273068

Sources:
DTC
METHYLBENZETHONIUM CHLORIDE HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL548615 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRICLABENDAZOLE HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL590927 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1546228 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1287983 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL600694 HSP90AA1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
POLAPREZINC HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

agonist (activating)

Interaction Info:

PMIDs:
None found

Sources:
DrugBank
ZERANOL HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL260342 HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL591137 HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL473721 HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1466186 HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TERPYRIDINE HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL599098 HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
POMIFERIN HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
IODOQUINOL HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THONZONIUM BROMIDE HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL599255 HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FLUCONAZOLE HSP90AA1

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CLOXYQUIN HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TRICLOSAN HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL428064 HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL538798 HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHLOROXINE HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SCLEROTIORIN HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL578944 HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ECONAZOLE NITRATE HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PYRITHIONE HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL591126 HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ITRACONAZOLE HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1224755 HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BIFONAZOLE HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KEPONE HSP90AA1

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ZEARALENONE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL533226 HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CETYLPYRIDINIUM BROMIDE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NANAOMYCIN HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYCLOHEXIMIDE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NITROXOLINE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL528694 HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1567571 HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DIACEREIN HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL523200 HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TETRACYCLINE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALEXIDINE HYDROCHLORIDE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CLIOQUINOL HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL2095095 HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AMLEXANOX HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
DICHLOROPHEN HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
FENTICLOR HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL53898 HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CALCIMYCIN HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
MICONAZOLE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CALMIDAZOLIUM CHLORIDE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PHENANTHROLINE HSP90AA1

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIRAM HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RHEIN HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
THIMEROSAL HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
KETOCONAZOLE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL578512 HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DAUNORUBICIN HYDROCHLORIDE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DOXORUBICIN HYDROCHLORIDE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL505670 HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
NORDIHYDROGUAIARETIC ACID HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CLOTRIMAZOLE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
WORTMANNIN HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
DISULFIRAM HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
HEXACHLOROPHENE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
QUERCETIN HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21798748

Sources:
DrugBank
DIPYRIDAMOLE HSP90AA1

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
COPPER HSP90AA1

Interaction Score: 0.0

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15359738

Sources:
DrugBank

Ensembl: ENSG00000080824
- Version: 101_38
Alternate Names:

HSP90AA1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
HopkinsGroom: P07900
- Version: 11-September-2012
Alternate Names:

3320 Entrez Gene Id

HSP90AA1 Uniprot Gene Name

HS90A_HUMAN Uniprot Id

Gene Info:

Interpro Short Name ATPase-like_ATP-bd

Uniprot Evidence 1: Evidence at protein level

Interpro Type Domain

Gene Categories:

DRUGGABLE GENOME

Publications:
RussLampel: ENSG00000080824
- Version: 26-July-2011
Alternate Names:

ENSG00000080824 Ensembl Gene Id

HSPCA Display Id

HEAT SHOCK PROTEIN HSP 90-ALPHA (HSP 86). [SOURCE:UNIPROT/SWISSPROT;ACC:P07900] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
TdgClinicalTrial: P07900
- Version: January-2014
Alternate Names:

HSP90AA1 Gene Symbol

Gene Info:

Target Class Miscellaneous

Target Subclass HSP90-like_chaperon

Publications:
CancerCommons: HSP90AA1
- Version: 25-July-2013
Alternate Names:

3320 Entrez Gene ID

Gene Info:

CancerCommons Reported Gene Name HSP90

Publications:
GuideToPharmacology: 3320
- Version: 29-September-2020
Alternate Names:

5253 HUGO Gene ID

5253 HUGO Gene Symbol

heat shock protein 90 alpha family class A member 1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name Heat shock proteins

GuideToPharmacology Gene Category ID 784

Publications:

DrugBank: BE0001120

Version: 5.1.7

Alternate Names:

HSP90AA1 DrugBank Gene Name

P07900 UniProt Accession

3320 Entrez Gene Id

Gene Info:

Publications:

Schnaider et al., 2000, The Hsp90-specific inhibitor geldanamycin selectively disrupts kinase-mediated signaling events of T-lymphocyte activation., Cell Stress Chaperones

Münster et al., 2001, Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells., Cancer Res.

Yang et al., 2001, Disruption of the EF-2 kinase/Hsp90 protein complex: a possible mechanism to inhibit glioblastoma by geldanamycin., Cancer Res.

DTC: HSP90AA1

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Hall JA et al., 2015, Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery., J Nat Prod

Li Z et al., 2014, Discovery of diamine-linked 17-aroylamido-17-demethoxygeldanamycins as potent Hsp90 inhibitors., Eur J Med Chem

Matts RL et al., 2011, A systematic protocol for the characterization of Hsp90 modulators., Bioorg Med Chem

MyCancerGenome: HSP90AA1
- Version: 20-Jun-2017
Alternate Names:

3320 Entrez Gene Id

HSP90AA1 MyCancerGenome Gene Symbol

HSP90 MyCancerGenome Reported Gene Name

Gene Info:

Publications:
HingoraniCasas: ENSG00000080824
- Version: 31-May-2017
Alternate Names:

ENSG00000080824 Gene Symbol

HSP90AA1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
ChemblInteractions: HSP90A
- Version: chembl_23
Alternate Names:

HSPC1 GENE_SYMBOL

HSPCA GENE_SYMBOL

HSP90AA1 GENE_SYMBOL

Gene Info:

Publications:
Pharos: HSP90AA1
- Version: 03-September-2020
Alternate Names:

Heat shock protein HSP 90-alpha Gene Name

P07900 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications:
GO: HSP90AA1
- Version: 05-September-2020
Alternate Names:

HSP90A GO Gene Synonym

HSPC1 GO Gene Synonym

HSPCA GO Gene Synonym

Gene Info:

Gene Categories:

CELL SURFACE

Publications:
Tempus: HSP90AA1
- Version: 11-November-2018
Alternate Names:

HSP90AA1 Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
TTD: Heat shock protein 90 alpha
- Version: 2020.06.01
Alternate Names:

HSP90A TTD Gene Abbreviation

T18477 TTD Target ID

Gene Info:

Publications:
MyCancerGenomeClinicalTrial: HSP90AA1
- Version: 30-February-2014
Alternate Names:

Gene Info:

Publications:
FoundationOneGenes: HSP90AA1
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
CarisMolecularIntelligence: HSP90AA1
- Version: 04-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:

Novel drug target	Novel Target
Trial Name	alvespimycin hydrochloride, KOS-1022 (DMAG), NSC-707545
Specific Action of the Ligand	Inhibition

Specific Action of the Ligand	Inhibition
Endogenous Drug?	False
Direct Interaction?	False

Trial Name	IPI-504
Novel drug target	Novel Target
Mechanism of Interaction	Heat shock protein HSP90 inhibitor

Mechanism of Interaction	Heat shock protein HSP90 inhibitor
Direct Interaction	yes
Trial Name	STA-9090

3320	Entrez Gene Id
HSP90AA1	Uniprot Gene Name
HS90A_HUMAN	Uniprot Id

ENSG00000080824	Ensembl Gene Id
HSPCA	Display Id
HEAT SHOCK PROTEIN HSP 90-ALPHA (HSP 86). [SOURCE:UNIPROT/SWISSPROT;ACC:P07900]	Description

5253	HUGO Gene ID
5253	HUGO Gene Symbol
heat shock protein 90 alpha family class A member 1	HUGO Gene Name

HSP90AA1	DrugBank Gene Name
P07900	UniProt Accession
3320	Entrez Gene Id

HSP90A	GO Gene Synonym
HSPC1	GO Gene Synonym
HSPCA	GO Gene Synonym

HSP90AA1 Gene Record

HSP90AA1 3320 Druggable GenomeClinically Actionable

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235