3269 |
HISTAMINE RECEPTOR H1 |
HRH1 |
H1-R |
H1R |
HH1R |
hisH1 |
600167 |
5182 |
ENSG00000196639 |
OTTHUMG00000129719 |
P35367 |
HISTAMINE H1 RECEPTOR |
HRH1_HUMAN |
HISTAMINE H1 RECEPTOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P35367] |
PA29456 |
T77913 |
Interpro Acc | IPR000276 |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Short Name | 7TM_GPCR_Rhodpsn |
Human Readable Name | DRUGGABLE GENOME |
Interpro Name | GPCR, rhodopsin-like, 7TM |
Human Readable Name | G PROTEIN COUPLED RECEPTOR |
Interpro Type | Family |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
Target Main Class | Receptors |
Target Class | Receptors |
Gene Biotype | PROTEIN_CODING |
G PROTEIN COUPLED RECEPTOR |
DRUGGABLE GENOME |
antagonist (inhibitory) |
Trial Name | Azelastine |
Novel drug target | Established target |
Trial Name | azelastine hydrochloride nasal spray,Astepro |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
Mechanism of Interaction | Histamine H1 receptor antagonist |
antagonist (inhibitory) |
Trial Name | bepotastine besilate,Bepreve, Talion |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Histamine H1 receptor antagonist |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
Trial Name | desloratadine , Clarinex |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Trial Name | levocetirizine dihydrochloride,Xusal, Xyzal |
Novel drug target | Established target |
n/a |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
Mechanism of Interaction | Histamine H1 receptor antagonist |
n/a |
Trial Name | vapitadine dihydrochloride,Hivenyl |
Novel drug target | Established target |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histamine H1 receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Trial Name | OBE101,Histalean |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Histamine H1 receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histamine H1 receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
Novel drug target | Established target |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histamine H1 receptor antagonist |
n/a |
Trial Name | GSK-1004723 |
Novel drug target | Established target |
antagonist (inhibitory) |
Novel drug target | Established target |
Trial Name | - |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histamine H1 receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histamine H1 receptor antagonist |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
n/a |
Novel drug target | Established target |
Trial Name | - |
antagonist (inhibitory) |
Trial Name | Asenapine |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | olanzapine,Zyprexa, Zypadhera, Zyprexa Relprevv |
Novel drug target | Established target |
Trial Name | Olanzapine/fluoxetine combination,Symbyax (Zyprexa/Prozac) |
antagonist (inhibitory) |
Trial Name | iloperidone,Fanapt, Fiapta, Zomaril |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
agonist (activating) |
Mechanism of Interaction | Histamine H1 receptor agonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Trial Name | - |
Novel drug target | Established target |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
antagonist (inhibitory) |
Mechanism of Interaction | Histamine H1 receptor antagonist |
Direct Interaction | yes |
HRH1 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HRH1_HUMAN | Uniprot Id |
HISTAMINE H1 RECEPTOR | Uniprot Protein Name |
HRH1 | Uniprot Gene Name |
Interpro Acc | IPR000276 |
Uniprot Status | Swiss-Prot |
Uniprot Evidence | 1: Evidence at protein level |
G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME |
HRH1 | Gene Symbol |
ENSG00000196639 | Ensembl Gene Id |
HRH1_HUMAN | Uniprot Id |
Transmembrane Helix Count | 7 |
Target Subclass | Rhodopsin |
Target Subclass | GPCR |
HRH1 | Gene Symbol |
Target Class | Receptors |
Target Subclass | GPCR |
Target Subclass | Rhodopsin |
HISTAMINE H1 RECEPTOR. [SOURCE:UNIPROT/SWISSPROT;ACC:P35367] | Description |
HRH1 | Display Id |
ENSG00000196639 | Ensembl Gene Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
PA29456 | PharmGKB ID |
H1R | TTD Gene Abbreviation |
T77913 | TTD Target ID |
ENSG00000196639 | Gene Symbol |
HRH1 | Ensembl Id |
DRUGGABLE GENOME |
HRH1 | GENE_SYMBOL |
Histamine H1 receptor | UNIPROT |
H1R | UNIPROT |
3269 | Gene ID |
H1-R | dGene Synonym |
hisH1 | dGene Synonym |
G PROTEIN COUPLED RECEPTOR |
G PROTEIN COUPLED RECEPTOR |