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HLA-DRB3 Gene Record

  • Summary
  • Interactions
  • Claims
  • HLA-DRB3 3125

    Alternate Names:

    3125
    MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS II, DR BETA 3
    HLA-DRB3
    HLA-DR1B
    HLA-DR3B
    612735
    4951
    P01903
    PA35074
    DRB3
    HLA-DPB1
    HLA-DRB3*

    Gene Info:

    Target Class Miscellaneous
    Target Subclass Ligand
    Target Subclass MHC
    (0 More Sources)

    Gene Categories: Category Details

    Publications:

    Karnes JH et al., 2017, Influence of Human Leukocyte Antigen (HLA) Alleles and Killer Cell Immunoglobulin-Like Receptors (KIR) Types on Heparin-Induced Thrombocytopenia (HIT)., Pharmacotherapy
    Dettling M et al., 2001, Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry., Pharmacogenetics
  • 1D09C3   HLA-DRB3

    Interaction Score: 6.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name 1D09C3
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • HEPARIN   HLA-DRB3

    Interaction Score: 1.42

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28688202


    Sources:
    PharmGKB

  • CLOZAPINE   HLA-DRB3

    Interaction Score: 0.7

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11266078


    Sources:
    PharmGKB

  • TdgClinicalTrial: P01903

    • Version: January-2014

    Alternate Names:
    HLA-DRB3 Gene Symbol

    Gene Info:
    Target Class Miscellaneous
    Target Subclass Ligand
    Target Subclass MHC

    Publications:

  • PharmGKB: HLA-DRB3

    • Version: 18-August-2020

    Alternate Names:
    PA35074 PharmGKB ID

    Gene Info:

    Publications:
    Karnes JH et al., 2017, Influence of Human Leukocyte Antigen (HLA) Alleles and Killer Cell Immunoglobulin-Like Receptors (KIR) Types on Heparin-Induced Thrombocytopenia (HIT)., Pharmacotherapy
    Dettling M et al., 2001, Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry., Pharmacogenetics

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21