• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

HLA-DPB1 Gene Record

  • Summary
  • Interactions
  • Claims
  • HLA-DPB1 3115 Druggable Genome

    Alternate Names:

    3115
    MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS II, DP BETA 1
    HLA-DPB1
    DPB1
    HLA-DP
    HLA-DP1B
    HLA-DPB
    142858
    4940
    ENSG00000223865
    OTTHUMG00000031076
    PA35064

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    DRUGGABLE GENOME

    Publications:

    Dettling M et al., 2001, Further evidence of human leukocyte antigen-encoded susceptibility to clozapine-induced agranulocytosis independent of ancestry., Pharmacogenetics
    Choi JH et al., 2004, HLA association in aspirin-intolerant asthma: DPB1*0301 as a strong marker in a Korean population., J Allergy Clin Immunol
    Kim SH et al., 2005, The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria., Clin Exp Allergy
    Lee HY et al., 2009, The HLA allele marker for differentiating ASA hypersensitivity phenotypes., Allergy
    Dekker JW et al., 1997, Aspirin-induced asthma and HLA-DRB1 and HLA-DPB1 genotypes., Clin Exp Allergy
  • ASPIRIN   HLA-DPB1

    Interaction Score: 1.95

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15007363 15784113 19392989 9179433


    Sources:
    PharmGKB

  • CLOZAPINE   HLA-DPB1

    Interaction Score: 0.71

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11266078


    Sources:
    PharmGKB

  • Ensembl: ENSG00000223865

    • Version: 101_38

    Alternate Names:
    HLA-DPB1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: HLA-DPB1

    • Version: 18-August-2020

    Alternate Names:
    PA35064 PharmGKB ID

    Gene Info:

    Publications:
    Choi JH et al., 2004, HLA association in aspirin-intolerant asthma: DPB1*0301 as a strong marker in a Korean population., J Allergy Clin Immunol
    Kim SH et al., 2005, The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria., Clin Exp Allergy
    Lee HY et al., 2009, The HLA allele marker for differentiating ASA hypersensitivity phenotypes., Allergy

  • HingoraniCasas: ENSG00000223865

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000223865 Gene Symbol
    HLA-DPB1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: HLA-DPB1

    • Version: 05-September-2020

    Alternate Names:
    HLA-DP1B GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

  • Tempus: HLA-DPB1

    • Version: 11-November-2018

    Alternate Names:
    HLA-DPB1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21