DGIdb - HLA-A Gene Record

HLA-A 3105 Druggable Genome

Alternate Names:

3105
MAJOR HISTOCOMPATIBILITY COMPLEX, CLASS I, A
HLA-A
HLAA
142800
4931
ENSG00000206503
OTTHUMG00000130501
PA35055

Gene Info:

Gene Biotype	PROTEIN_CODING

(3 More Sources)

Gene Categories: Category Details

CELL SURFACE
DRUGGABLE GENOME

Publications:

Kaniwa N et al., 2013, Specific HLA types are associated with antiepileptic drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese subjects., Pharmacogenomics
Hirata K et al., 2008, Ticlopidine-induced hepatotoxicity is associated with specific human leukocyte antigen genomic subtypes in Japanese patients: a preliminary case-control study., Pharmacogenomics J
Farag RE et al., 2013, Human leukocyte antigen class I alleles can predict response to pegylated interferon/ribavirin therapy in chronic hepatitis C Egyptian patients., Arch Iran Med
Nakkam N et al., 2020, Cross-reactivity between vancomycin, teicoplanin, and telavancin in patients with HLA-A∗32:01-positive vancomycin-induced DRESS sharing an HLA class II haplotype., J Allergy Clin Immunol
Yang TW et al., 2018, HLA-A*11:01 is associated with levetiracetam-induced psychiatric adverse events., PLoS One
Yue Z et al., 2018, Amino Acid Variants of HLA-DRB1 Confer Susceptibility to Dapsone Hypersensitivity Syndrome in Addition to HLA-B*13:01., J Invest Dermatol
Romano A et al., 1998, Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes., Ann Allergy Asthma Immunol

BACAMPICILLIN HLA-A

Interaction Score: 8.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9609616

Sources:
PharmGKB
VANCOMYCIN HLA-A

Interaction Score: 8.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
32439433

Sources:
PharmGKB
IPILIMUMAB HLA-A

Interaction Score: 1.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB FDA
TERBINAFINE HLA-A

Interaction Score: 1.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
LEVETIRACETAM HLA-A

Interaction Score: 1.18

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
30020991

Sources:
PharmGKB
DAPSONE HLA-A

Interaction Score: 0.82

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
29233746

Sources:
PharmGKB
AMPICILLIN HLA-A

Interaction Score: 0.75

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9609616

Sources:
PharmGKB
TICLOPIDINE HLA-A

Interaction Score: 0.63

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17339877

Sources:
PharmGKB
CLAVULANIC ACID HLA-A

Interaction Score: 0.59

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
AMOXICILLIN HLA-A

Interaction Score: 0.48

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9609616

Sources:
PharmGKB
ZONISAMIDE HLA-A

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24236482

Sources:
PharmGKB
RIBAVIRIN HLA-A

Interaction Score: 0.26

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23360626

Sources:
PharmGKB
SERTRALINE HLA-A

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
FENOFIBRATE HLA-A

Interaction Score: 0.14

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
CARBAMAZEPINE HLA-A

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
FDA

Ensembl: ENSG00000206503
- Version: 101_38
Alternate Names:

HLA-A Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: HLA-A

Version: 18-August-2020

Alternate Names:

PA35055 PharmGKB ID

Gene Info:

Publications:

Yue Z et al., 2018, Amino Acid Variants of HLA-DRB1 Confer Susceptibility to Dapsone Hypersensitivity Syndrome in Addition to HLA-B*13:01., J Invest Dermatol

Romano A et al., 1998, Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes., Ann Allergy Asthma Immunol

Farag RE et al., 2013, Human leukocyte antigen class I alleles can predict response to pegylated interferon/ribavirin therapy in chronic hepatitis C Egyptian patients., Arch Iran Med

NCI: HLA-A

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Madsen et al., 1981, Decreased expression of HLA-DR antigens on peripheral blood B lymphocytes during glucocorticoid treatment., Tissue Antigens

Hoon et al., 1998, Is the survival of melanoma patients receiving polyvalent melanoma cell vaccine linked to the human leukocyte antigen phenotype of patients?, J. Clin. Oncol.

Fischer et al., 1984, HLA -A, -B, -C and -DR antigens in individuals with sensitivity to cobalt., Acta Derm. Venereol.

HingoraniCasas: ENSG00000206503
- Version: 31-May-2017
Alternate Names:

ENSG00000206503 Gene Symbol

HLA-A Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: HLA-A
- Version: 01-February-2022
Alternate Names:

HLAA GO Gene Synonym

Gene Info:

Gene Categories:

CELL SURFACE

Publications:
Tempus: HLA-A
- Version: 11-November-2018
Alternate Names:

HLA-A Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
FDA: HLA-A
- Version: 04-September-2020
Alternate Names:

Gene Info:

Publications:

HLA-A Gene Record

HLA-A 3105 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9609616

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 32439433

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB FDA

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 30020991

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 29233746

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9609616

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17339877

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9609616

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24236482

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23360626

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: FDA

Ensembl: ENSG00000206503

Alternate Names: HLA-A Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: HLA-A

Alternate Names: PA35055 PharmGKB ID

Gene Info:

NCI: HLA-A

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000206503

Alternate Names: ENSG00000206503 Gene Symbol HLA-A Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Interaction Types & Directionality:

n/a

PMIDs:
9609616

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
32439433

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB FDA

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
30020991

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
29233746

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
9609616

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
17339877

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
9609616

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
24236482

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
23360626

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
FDA

Alternate Names:

HLA-A Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PA35055 PharmGKB ID

Alternate Names:

ENSG00000206503 Gene Symbol

HLA-A Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

HLAA GO Gene Synonym

Gene Categories:

CELL SURFACE

Alternate Names:

HLA-A Gene Symbol

Gene Categories:

CLINICALLY ACTIONABLE