79885 |
HISTONE DEACETYLASE 11 |
HDAC11 |
HD11 |
607226 |
19086 |
ENSG00000163517 |
OTTHUMG00000129800 |
Q96DB2 |
2615 |
PA38793 |
T97903 |
NP_079103 |
NM_024827 |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
Gene Biotype | PROTEIN_CODING |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
TRANSCRIPTION FACTOR BINDING |
DRUGGABLE GENOME |
ENZYME |
inhibitor (inhibitory) |
Trial Name | MGCD-0103 |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase 11 |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
Trial Name | PXD101 |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Trial Name | CUDC-101 |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Novel drug target | Established target |
Trial Name | Panobinostat |
Notes |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Trial Name | Depsipeptide |
Novel drug target | Established target |
Mechanism of Interaction | Histone deacetylase inhibitor |
inhibitor (inhibitory) |
Mechanism of Interaction | Histone deacetylase inhibitor |
Direct Interaction | yes |
n/a |
Trial Name | Resminostat |
Novel drug target | Established target |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
n/a |
Novel drug target | Established target |
Trial Name | SB939 |
n/a |
Trial Name | AR-42 |
Novel drug target | Established target |
HDAC11 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
HDAC11 | Gene Symbol |
Target Class | Enzymes |
Target Subclass | EC:3.5.1.98 |
19086 | HUGO Gene ID |
19086 | HUGO Gene Symbol |
histone deacetylase 11 | HUGO Gene Name |
GuideToPharmacology Gene Category Name | 3.5.1.- Histone deacetylases (HDACs) |
GuideToPharmacology Gene Category ID | 848 |
ENZYME |
PA38793 | PharmGKB ID |
HDAC11 | Gene Symbol |
HDAC11 | GENE_SYMBOL |
Histone deacetylase 11 | UNIPROT |
HD11 | UNIPROT |
ENSG00000163517 | Gene Symbol |
HDAC11 | Ensembl Id |
DRUGGABLE GENOME |
HDAC11 | TTD Gene Abbreviation |
T97903 | TTD Target ID |
TRANSCRIPTION FACTOR BINDING |