• Search
      • Search Interactions Search Categories
    • Browse
      • Browse Categories Browse Sources
    • Information
      • About Publications Interaction Types & Directionalities Interaction Score & Query Score API Documentation FAQ Known Data Clients News Contact
    • Downloads
      • Data Source Code

GUCA2B Gene Record

  • Summary
  • Interactions
  • Claims
  • GUCA2B 2981 Druggable Genome

    Alternate Names:

    2981
    GUANYLATE CYCLASE ACTIVATOR 2B
    GUCA2B
    GCAP-II
    UGN
    601271
    4683
    ENSG00000044012
    OTTHUMG00000007024
    Q16661

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Wang et al., 2003, Effects of uroguanylin, an intestinal natriuretic peptide, on tubuloglomerular feedback., Hypertens. Res.
    Carrithers et al., 2002, Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine., Regul. Pept.
    Carrithers et al., 1999, Renal effects of uroguanylin and guanylin in vivo., Braz. J. Med. Biol. Res.
  • VOLANESORSEN SODIUM   GUCA2B

    Interaction Score: 20.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12924626 12137970 10559834


    Sources:
    NCI

  • Ensembl: ENSG00000044012

    • Version: 101_38

    Alternate Names:
    GUCA2B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: GUCA2B

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Steinbrecher et al., 2001, Increases in guanylin and uroguanylin in a mouse model of osmotic diarrhea are guanylate cyclase C-independent., Gastroenterology
    Carrithers et al., 2002, Site-specific effects of dietary salt intake on guanylin and uroguanylin mRNA expression in rat intestine., Regul. Pept.
    Wang et al., 2003, Effects of uroguanylin, an intestinal natriuretic peptide, on tubuloglomerular feedback., Hypertens. Res.

  • HingoraniCasas: ENSG00000044012

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000044012 Gene Symbol
    GUCA2B Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • Pharos: GUCA2B

    • Version: 01-February-2022

    Alternate Names:
    Guanylate cyclase activator 2B Gene Name
    Q16661 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21