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GUCA2A Gene Record

  • Summary
  • Interactions
  • Claims
  • GUCA2A 2980 Druggable Genome

    Alternate Names:

    2980
    GUANYLATE CYCLASE ACTIVATOR 2A
    GUCA2A
    GCAP-I
    GUCA2
    STARA
    139392
    4682
    ENSG00000197273
    OTTHUMG00000007023
    Guanylin
    Q02747

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (1 More Sources)

    Gene Categories: Category Details

    HORMONE ACTIVITY
    DRUGGABLE GENOME
    ENZYME

    Publications:

    Kita et al., 1999, Marked increase of guanylin secretion in response to salt loading in the rat small intestine., Am. J. Physiol.
    Steinbrecher et al., 2001, Increases in guanylin and uroguanylin in a mouse model of osmotic diarrhea are guanylate cyclase C-independent., Gastroenterology
    Furuya et al., 1998, Intravenous injection of guanylin induces mucus secretion from goblet cells in rat duodenal crypts., Anat. Embryol.
  • LACTOSE, ANHYDROUS   GUCA2A

    Interaction Score: 5.89

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11677212


    Sources:
    NCI

  • ATROPINE   GUCA2A

    Interaction Score: 3.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9623669


    Sources:
    NCI

  • VOLANESORSEN SODIUM   GUCA2A

    Interaction Score: 3.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10564101


    Sources:
    NCI

  • Ensembl: ENSG00000197273

    • Version: 101_38

    Alternate Names:
    GUCA2A Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: GUCA2A

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Steinbrecher et al., 2001, Increases in guanylin and uroguanylin in a mouse model of osmotic diarrhea are guanylate cyclase C-independent., Gastroenterology
    Kita et al., 1999, Marked increase of guanylin secretion in response to salt loading in the rat small intestine., Am. J. Physiol.
    Furuya et al., 1998, Intravenous injection of guanylin induces mucus secretion from goblet cells in rat duodenal crypts., Anat. Embryol.

  • HingoraniCasas: ENSG00000197273

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000197273 Gene Symbol
    GUCA2A Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GO: GUCA2A

    • Version: 01-February-2022

    Alternate Names:
    GUCA2 GO Gene Synonym

    Gene Info:

    Gene Categories:
    HORMONE ACTIVITY

    Publications:

  • Pharos: GUCA2A

    • Version: 01-February-2022

    Alternate Names:
    Guanylin Gene Name
    Q02747 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21