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GSTP1 Gene Record

  • Summary
  • Interactions
  • Claims
  • GSTP1 2950 Druggable Genome

    Alternate Names:

    2950
    GLUTATHIONE S-TRANSFERASE PI 1
    GSTP1
    DFN7
    FAEES3
    GST3
    GSTP
    HEL-S-22
    PI
    134660
    4638
    ENSG00000084207
    OTTHUMG00000137430
    P09211
    GST class-pi
    GSTP1-1
    Glutathione S-transferase P
    2473
    PA29028
    T21669

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.5.1.18
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Sawers et al., 2014, Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines., Br. J. Cancer
    Clemens E et al., 2020, Genetic variation of cisplatin-induced ototoxicity in non-cranial-irradiated pediatric patients using a candidate gene approach: The International PanCareLIFE Study., Pharmacogenomics J
    Goričar K et al., 2015, Genetic variability of DNA repair mechanisms and glutathione-S-transferase genes influences treatment outcome in osteosarcoma., Cancer Epidemiol
    Khrunin A et al., 2012, Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins., Pharmacogenomics
    Khrunin AV et al., 2010, Genetic polymorphisms and the efficacy and toxicity of cisplatin-based chemotherapy in ovarian cancer patients., Pharmacogenomics J
    Booton R et al., 2006, Glutathione-S-transferase P1 isoenzyme polymorphisms, platinum-based chemotherapy, and non-small cell lung cancer., J Thorac Oncol
    Kimura S et al., 2004, The relationship of the human glutathione S-transferase P1 polymorphism and chemotherapeutic sensitivity in head and neck squamous carcinoma., Int J Mol Med
    Hour et al., Characterization of chemoresistance mechanisms in a series of cisplatin-resistant transitional carcinoma cell lines., Anticancer Res.
    Sugishita M et al., 2016, Pharmacogenetic association between GSTP1 genetic polymorphism and febrile neutropenia in Japanese patients with early breast cancer., Breast Cancer
    Zhang BL et al., 2011, Polymorphisms of GSTP1 is associated with differences of chemotherapy response and toxicity in breast cancer., Chin Med J (Engl)
    Oliveira AL et al., 2010, GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer., Genet Mol Res
    Lin et al., 2001, GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells., Am. J. Pathol.
    Ishimoto et al., 2002, Allelic variants of the human glutathione S-transferase P1 gene confer differential cytoprotection against anticancer agents in Escherichia coli., Pharmacogenetics
    Anderer et al., 2000, Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia., Pharmacogenetics
    Meulendijks D et al., 2017, Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies., Pharmacogenomics J
    Lamas MJ et al., 2011, Use of a comprehensive panel of biomarkers to predict response to a fluorouracil-oxaliplatin regimen in patients with metastatic colorectal cancer., Pharmacogenomics
    Agostini M et al., 2008, Glutathione S-transferase P1 Ile105Val polymorphism is associated with haematological toxicity in elderly rectal cancer patients receiving preoperative chemoradiotherapy., Drugs Aging
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Chan SL et al., 2017, Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients., PLoS One
    Wu S et al., 2016, Genetic Polymorphisms of Glutathione S-Transferase P1 (GSTP1) and the Incidence of Anti-Tuberculosis Drug-Induced Hepatotoxicity., PLoS One
    He L et al., 2015, Involvement of cytochrome P450 1A1 and glutathione S-transferase P1 polymorphisms and promoter hypermethylation in the progression of anti-tuberculosis drug-induced liver injury: a case-control study., PLoS One
    Thompson P et al., 2014, Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children's Oncology Group., Cancer Chemother Pharmacol
    Rosen et al., 2003, Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies., Clin. Cancer Res.
    Kavanagh et al., Multi-institutional phase 2 study of TLK286 (TELCYTA, a glutathione S-transferase P1-1 activated glutathione analog prodrug) in patients with platinum and paclitaxel refractory or resistant ovarian cancer., Int. J. Gynecol. Cancer
    Li et al., 1999, [Modulation of multiple drug resistance by nomegestrol acetate and droloxifene in K562/A02]., Zhonghua Xue Ye Xue Za Zhi
    Kishi S et al., 2004, Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia., Blood
    Dahllöf et al., Characterization of multidrug resistance in SEWA mouse tumor cells: increased glutathione transferase activity and reversal of resistance with verapamil., Anticancer Res.
    Kuga et al., 1997, Fibronectin fragment-facilitated retroviral transfer of the glutathione-S-transferase pi gene into CD34+ cells to protect them against alkylating agents., Hum. Gene Ther.
    Stoehlmacher et al., 2002, Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer., J. Natl. Cancer Inst.
    McLeod HL et al., 2010, Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741., J Clin Oncol
    Kim HS et al., 2009, Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: a Korean population-based study., Gynecol Oncol
    Stoehlmacher J et al., 2004, A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer., Br J Cancer
    Wild CP et al., 2000, Environmental and genetic determinants of aflatoxin-albumin adducts in the Gambia., Int J Cancer
    Watson MA et al., 1998, Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution., Carcinogenesis
    Ruzzo A et al., 2007, Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFOX-4 chemotherapy., J Clin Oncol
    Lecomte T et al., 2006, Glutathione S-transferase P1 polymorphism (Ile105Val) predicts cumulative neuropathy in patients receiving oxaliplatin-based chemotherapy., Clin Cancer Res
    Georgiadis P et al., 2004, Impact of phase I or phase II enzyme polymorphisms on lymphocyte DNA adducts in subjects exposed to urban air pollution and environmental tobacco smoke., Toxicol Lett
    Dandara C et al., 2002, Genetic polymorphism of cytochrome P450 1A1 (Cyp1A1) and glutathione transferases (M1, T1 and P1) among Africans., Clin Chem Lab Med
    Garte S et al., 2001, Metabolic gene polymorphism frequencies in control populations., Cancer Epidemiol Biomarkers Prev
    Gsur A et al., 2001, Polymorphisms of glutathione-S-transferase genes (GSTP1, GSTM1 and GSTT1) and prostate-cancer risk., Int J Cancer
    de Waziers et al., 1992, Effects of ethanol, dexamethasone and RU 486 on expression of cytochromes P450 2B, 2E, 3A and glutathione transferase pi in a rat hepatoma cell line (Fao)., Pharmacogenetics
    Hansson et al., 1991, Sensitization of human melanoma cells to the cytotoxic effect of melphalan by the glutathione transferase inhibitor ethacrynic acid., Cancer Res.
    Harkey et al., 2005, Overexpression of glutathione-S-transferase, MGSTII, confers resistance to busulfan and melphalan., Cancer Invest.
    Kashfi et al., 1995, Comparative effects of omeprazole on xenobiotic metabolizing enzymes in the rat and human., Clin. Pharmacol. Ther.
    Kravchenko et al., [The effect of selenium on enzymes metabolizing xenobiotics in rat liver]., Vopr. Med. Khim.
    Benson et al., 1985, Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs., Cancer Res.
    Mollerup et al., 2001, Lung carcinogenesis: resveratrol modulates the expression of genes involved in the metabolism of PAH in human bronchial epithelial cells., Int. J. Cancer
    Zielińska et al., 2005, Role of GSTM1, GSTP1, and GSTT1 gene polymorphism in ifosfamide metabolism affecting neurotoxicity and nephrotoxicity in children., J. Pediatr. Hematol. Oncol.
    Bakker et al., 2002, Methyl-CpG binding domain protein 2 represses transcription from hypermethylated pi-class glutathione S-transferase gene promoters in hepatocellular carcinoma cells., J. Biol. Chem.
    Zhong et al., 2002, Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas., Clin. Cancer Res.
    Yin JY et al., 2016, Pharmacogenomics of platinum-based chemotherapy sensitivity in NSCLC: toward precision medicine., Pharmacogenomics
    Depeille et al., 2005, Combined effects of GSTP1 and MRP1 in melanoma drug resistance., Br. J. Cancer
    van Iersel ML et al., 1997, Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1., Chem Biol Interact
    Okamura et al., 2000, NADPH/quinone oxidoreductase is a priority target of glioblastoma chemotherapy., Int. J. Oncol.
    Deffie et al., 1988, Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia., Cancer Res.
    Zhang et al., 1992, A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure., Proc. Natl. Acad. Sci. U.S.A.
    Ralat et al., 2006, Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi., Biochemistry
    Ishii et al., 2004, GSTP1 affects chemoresistance against camptothecin in human lung adenocarcinoma cells., Cancer Lett.
    Mukanganyama S et al., 2002, Inhibition of glutathione S-transferases by antimalarial drugs possible implications for circumventing anticancer drug resistance., Int J Cancer
    Adams et al., 1985, Altered mouse bone marrow glutathione and glutathione transferase levels in response to cytotoxins., Cancer Res.
    Silva et al., 2004, GSTM1, GSTT1, and GSTP1 genotypes and the genotoxicity of hydroquinone in human lymphocytes., Environ. Mol. Mutagen.
    Kumar et al., 1986, Inhibition of glutathione peroxidase and glutathione transferase in mouse liver by misonidazole., Biochem. Pharmacol.
    Breinholt et al., 2000, Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat., Cancer Lett.
    Harbottle A et al., 2001, Role of glutathione S-transferase P1, P-glycoprotein and multidrug resistance-associated protein 1 in acquired doxorubicin resistance., Int J Cancer
    Munday et al., 2001, Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinone reductase and glutathione transferase in rat tissues., Nutr Cancer
  • CANFOSFAMIDE   GSTP1

    Interaction Score: 5.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name TLK286
    Novel drug target Novel Target

    PMIDs:
    12738715 16014111


    Sources:
    TdgClinicalTrial TTD

  • EZATIOSTAT   GSTP1

    Interaction Score: 3.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name ezatiostat hydrochloride, TLK-199,Telintra
    Novel drug target Novel Target

    PMIDs:
    10592235


    Sources:
    TdgClinicalTrial TTD

  • EXATECAN MESYLATE   GSTP1

    Interaction Score: 1.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10639573


    Sources:
    NCI

  • EZATIOSTAT HYDROCHLORIDE   GSTP1

    Interaction Score: 1.29

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Glutathione S-transferase Pi inhibitor

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • SELENOMETHIONINE   GSTP1

    Interaction Score: 1.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1759407


    Sources:
    NCI

  • MISONIDAZOLE   GSTP1

    Interaction Score: 0.86

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3753520


    Sources:
    NCI

  • OXALIPLATIN   GSTP1

    Interaction Score: 0.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12072547 27995989 22188361 21449681 20530282 19203783 15213713 10728587 9498276 17409936 17401013 16707601 15093273 12435115 11751440 11307147


    Sources:
    NCI PharmGKB

  • PERFOSFAMIDE   GSTP1

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9382956


    Sources:
    NCI

  • DROLOXIFENE   GSTP1

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11721384


    Sources:
    NCI

  • ISONIAZID   GSTP1

    Interaction Score: 0.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29036176 27281183 25798582


    Sources:
    PharmGKB

  • SULFORAPHANE   GSTP1

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1549603


    Sources:
    NCI

  • IRINOTECAN HYDROCHLORIDE   GSTP1

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10639573


    Sources:
    NCI

  • DITIOCARB   GSTP1

    Interaction Score: 0.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2992773


    Sources:
    NCI

  • DECITABINE   GSTP1

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11960994 11948118


    Sources:
    NCI

  • LYCOPENE   GSTP1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10806309


    Sources:
    NCI

  • IFOSFAMIDE   GSTP1

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16282887


    Sources:
    NCI

  • RIFAMPIN   GSTP1

    Interaction Score: 0.27

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    29036176 27281183 25798582


    Sources:
    PharmGKB

  • GARLIC   GSTP1

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11962257


    Sources:
    NCI

  • PYRIMETHAMINE   GSTP1

    Interaction Score: 0.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11807801


    Sources:
    PharmGKB

  • VITAMIN E   GSTP1

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17029404


    Sources:
    NCI

  • BUSULFAN   GSTP1

    Interaction Score: 0.23

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15779864


    Sources:
    NCI PharmGKB

  • MELPHALAN   GSTP1

    Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1988111 15779864


    Sources:
    NCI

  • PLATINUM   GSTP1

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27462924


    Sources:
    PharmGKB

  • EPIRUBICIN   GSTP1

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25008867 21362365 20568049


    Sources:
    PharmGKB

  • THIOTEPA   GSTP1

    Interaction Score: 0.16

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • HYDROQUINONE   GSTP1

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15141365


    Sources:
    NCI

  • ADRIAMYCIN   GSTP1

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    2897875


    Sources:
    NCI

  • CYCLOPHOSPHAMIDE   GSTP1

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25008867 22188361 21362365 20568049 19786980 9382956


    Sources:
    NCI PharmGKB

  • CISPLATIN   GSTP1

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25010864 31666714 25592234 22188361 19786980 17409936 15254763 11062746


    Sources:
    NCI CIViC PharmGKB

  • PREDNISONE   GSTP1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11186134


    Sources:
    NCI

  • OMEPRAZOLE   GSTP1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8529327


    Sources:
    NCI

  • VERAPAMIL   GSTP1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3566185


    Sources:
    NCI

  • AZACITIDINE   GSTP1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11696442


    Sources:
    NCI

  • CAMPTOTHECIN   GSTP1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15500952


    Sources:
    NCI

  • BLEOMYCIN   GSTP1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • CARBOPLATIN   GSTP1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12360105 25010864


    Sources:
    NCI CIViC

  • CYTARABINE   GSTP1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    3978635


    Sources:
    NCI

  • RESVERATROL   GSTP1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11279601


    Sources:
    NCI

  • CURCUMIN   GSTP1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15999103 9463521


    Sources:
    NCI

  • ETOPOSIDE   GSTP1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12969965


    Sources:
    PharmGKB

  • FLUOROURACIL   GSTP1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27995989 21449681 18540691


    Sources:
    PharmGKB

  • LEUCOVORIN   GSTP1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    PharmGKB

  • DAUNORUBICIN   GSTP1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25119182


    Sources:
    PharmGKB

  • DOCETAXEL   GSTP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10639573


    Sources:
    NCI

  • DEXAMETHASONE   GSTP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1302037


    Sources:
    NCI

  • ALCOHOL   GSTP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1302037


    Sources:
    NCI

  • DOXORUBICIN   GSTP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11351295


    Sources:
    PharmGKB

  • PACLITAXEL   GSTP1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    25010864


    Sources:
    CIViC

  • Ensembl: ENSG00000084207

    • Version: 101_38

    Alternate Names:
    GSTP1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • TdgClinicalTrial: P09211

    • Version: January-2014

    Alternate Names:
    GSTP1 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.5.1.18

    Publications:

  • PharmGKB: GSTP1

    • Version: 18-August-2020

    Alternate Names:
    PA29028 PharmGKB ID

    Gene Info:

    Publications:
    Yin JY et al., 2016, Pharmacogenomics of platinum-based chemotherapy sensitivity in NSCLC: toward precision medicine., Pharmacogenomics
    Wild CP et al., 2000, Environmental and genetic determinants of aflatoxin-albumin adducts in the Gambia., Int J Cancer
    Khrunin A et al., 2012, Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins., Pharmacogenomics

  • CIViC: GSTP1

    • Version: 14-September-2020

    Alternate Names:
    2950 Entrez Gene ID
    2473 CIViC Gene ID

    Gene Info:

    Publications:
    Chen et al., 2010, Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma., Cancer Sci.
    Sawers et al., 2014, Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines., Br. J. Cancer

  • NCI: GSTP1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Anderer et al., 2000, Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia., Pharmacogenetics
    Stoehlmacher et al., 2002, Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer., J. Natl. Cancer Inst.
    de Waziers et al., 1992, Effects of ethanol, dexamethasone and RU 486 on expression of cytochromes P450 2B, 2E, 3A and glutathione transferase pi in a rat hepatoma cell line (Fao)., Pharmacogenetics

  • HingoraniCasas: ENSG00000084207

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000084207 Gene Symbol
    GSTP1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: FAEES3

    • Version: chembl_23

    Alternate Names:
    GST3 GENE_SYMBOL
    GSTP1 GENE_SYMBOL
    Glutathione S-transferase P UNIPROT

    Gene Info:

    Publications:

  • Tempus: GSTP1

    • Version: 11-November-2018

    Alternate Names:
    GSTP1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • TTD: Glutathione S-transferase P

    • Version: 2020.06.01

    Alternate Names:
    GSTP1 TTD Gene Abbreviation
    T21669 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: GSTP1

    • Version: 01-February-2022

    Alternate Names:
    Glutathione S-transferase P Gene Name
    P09211 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21