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GSR 2936 Druggable Genome
Alternate Names:
2936 GLUTATHIONE-DISULFIDE REDUCTASE GSR HEL-75 HEL-S-122m 138300 4623 ENSG00000104687 OTTHUMG00000163946 P00390 GSHR_HUMAN GLUTATHIONE REDUCTASE, MITOCHONDRIAL GLUR GRase GRD1 GR 2613 GLUTATHIONE REDUCTASE, MITOCHONDRIAL PRECURSOR (EC 1.8.1.7) (GR) (GRASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P00390] PA29014 Glutamine receptor T21447 NM_000637 NP_000628 GSRD Gene Info:
Target Class Enzymes Target Subclass EC:1.8.1.7 Uniprot Evidence 1: Evidence at protein level Interpro Name Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain Interpro Acc IPR001327 Interpro Type Domain Human Readable Name DRUGGABLE GENOME Uniprot Status Swiss-Prot Interpro Short Name Pyr_OxRdtase_NAD-bd_dom Target Subclass 1.8.1.7 Target Main Class Enzymes Gene Biotype PROTEIN_CODING GuideToPharmacology Gene Category Name 1.-.-.- Oxidoreductases GuideToPharmacology Gene Category ID 840 Gene Categories: Category Details
EXTERNAL SIDE OF PLASMA MEMBRANE DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 6.38
Interaction Types & Directionality:
inhibitor (inhibitory) substrate Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
Interaction Score: 4.25
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Trial Name polifeprosan 20/carmustine,Gliadel Novel drug target Established target Mechanism of Interaction Glutathione reductase inhibitor -
Interaction Score: 4.25
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Interaction Score: 2.84
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Interaction Score: 2.13
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Interaction Score: 1.7
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Interaction Score: 1.42
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Interaction Score: 0.95
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Interaction Score: 0.45
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Interaction Score: 0.33
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Interaction Score: 0.11
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- Version: 101_38
Alternate Names:
GSR Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: January-2014
Alternate Names:
GSR Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:1.8.1.7 Publications:
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Alternate Names:
ENSG00000104687 Ensembl Gene Id P00390 Uniprot Accession GSHR_HUMAN Uniprot Id Gene Info:
Target Subclass 1.8.1.7 Target Main Class Enzymes Publications:
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- Version: 11-September-2012
Alternate Names:
GLUTATHIONE REDUCTASE, MITOCHONDRIAL Uniprot Protein Name 2936 Entrez Gene Id GSR Uniprot Gene Name Gene Info:
Uniprot Evidence 1: Evidence at protein level Interpro Name Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain Interpro Acc IPR001327 Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 26-July-2011
Alternate Names:
GSR Display Id GLUTATHIONE REDUCTASE, MITOCHONDRIAL PRECURSOR (EC 1.8.1.7) (GR) (GRASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P00390] Description ENSG00000104687 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
4623 HUGO Gene ID 4623 HUGO Gene Symbol glutathione-disulfide reductase HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name 1.-.-.- Oxidoreductases GuideToPharmacology Gene Category ID 840 Gene Categories:
ENZYME Publications:
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Alternate Names:
PA29014 PharmGKB ID Gene Info:
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Alternate Names:
Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000104687 Gene Symbol GSR Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
GRD1 GENE_SYMBOL GSR GENE_SYMBOL Glutathione reductase, mitochondrial UNIPROT Gene Info:
Publications:
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- Version: 2020.06.01
Alternate Names:
GluR TTD Gene Abbreviation T21447 TTD Target ID Gene Info:
Publications:
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Alternate Names:
GLUR GO Gene Synonym GRD1 GO Gene Synonym Gene Info:
Gene Categories:
EXTERNAL SIDE OF PLASMA MEMBRANE Publications:
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Alternate Names:
Glutathione reductase, mitochondrial Gene Name P00390 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: