DGIdb - GSK3B Gene Record

GSK3B 2932 Druggable GenomeClinically Actionable

Alternate Names:

2932
GLYCOGEN SYNTHASE KINASE 3 BETA
GSK3B
605004
4617
ENSG00000082701
OTTHUMG00000133765
P49841
GSK3B_HUMAN
GLYCOGEN SYNTHASE KINASE-3 BETA
GSK-3 beta
Serine/threonine-protein kinase GSK3B
GLYCOGEN SYNTHASE KINASE-3 BETA (EC 2.7.1.37) (GSK-3 BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49841]
PA29009
GSK-3B
T70977
-

Gene Info:

Target Class	Enzymes
Target Subclass	EC:2.7.11.26
Uniprot Status	Swiss-Prot
Interpro Short Name	Ser/Thr_dual-sp_kinase_dom
Human Readable Name	DRUGGABLE GENOME
Uniprot Evidence	1: Evidence at protein level
Interpro Type	Domain
Human Readable Name	KINASE
Interpro Name	Serine/threonine- / dual-specificity protein kinase, catalytic domain
Interpro Acc	IPR002290
Gene Biotype	PROTEIN_CODING

(12 More Sources)

Gene Categories: Category Details

KINASE
SERINE THREONINE KINASE
DRUGGABLE GENOME
CLINICALLY ACTIONABLE
TRANSCRIPTION FACTOR

Publications:

Martinez A et al., 2011, Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment., Int J Alzheimers Dis
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Ha do T et al., 2009, Palbinone and triterpenes from Moutan Cortex (Paeonia suffruticosa, Paeoniaceae) stimulate glucose uptake and glycogen synthesis via activation of AMPK in insulin-resistant human HepG2 Cells., Bioorg Med Chem Lett
Zou H et al., 2010, Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode., J Med Chem
Zhang P et al., 2014, Novel benzothiazinones (BTOs) as allosteric modulator or substrate competitive inhibitor of glycogen synthase kinase 3β (GSK-3β) with cellular activity of promoting glucose uptake., Bioorg Med Chem Lett
Schmöle AC et al., 2010, Novel indolylmaleimide acts as GSK-3beta inhibitor in human neural progenitor cells., Bioorg Med Chem
Borsotto et al., 2007, PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder., Pharmacogenomics J.
Adli et al., 2007, Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism., Biol. Psychiatry
O'Brien et al., 2009, Validating GSK3 as an in vivo target of lithium action., Biochem. Soc. Trans.
Salloum NC et al., 2014, Towards the clinical implementation of pharmacogenetics in bipolar disorder., BMC Med
Lin YF et al., 2013, Glycogen synthase kinase 3β gene polymorphisms may be associated with bipolar I disorder and the therapeutic response to lithium., J Affect Disord
McCarthy MJ et al., 2011, Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder., Genes Brain Behav
McCarthy MJ et al., 2010, Pharmacogenetics of lithium response in bipolar disorder., Pharmacogenomics
Rao KV et al., 2006, Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases., J Nat Prod
Tsai SJ et al., 2008, Glycogen synthase kinase-3beta gene is associated with antidepressant treatment response in Chinese major depressive disorder., Pharmacogenomics J
Bidon-Chanal A et al., 2013, Evidence for a new binding mode to GSK-3: allosteric regulation by the marine compound palinurin., Eur J Med Chem
Hudkins RL et al., 2012, Synthesis and biological profile of the pan-vascular endothelial growth factor receptor/tyrosine kinase with immunoglobulin and epidermal growth factor-like homology domains 2 (VEGF-R/TIE-2) inhibitor 11-(2-methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one (CEP-11981): a novel oncology therapeutic agent., J Med Chem
Kang NS et al., 2009, Identification of small molecules that inhibit GSK-3beta through virtual screening., Bioorg Med Chem Lett
Chao WR et al., 2007, Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling., J Med Chem

CHEMBL449063 GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19081248

Sources:
DTC
SITOGLUSIDE GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
CHEMBL1081326 GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
PALINURIN GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23354070

Sources:
DTC
BETA-SITOSTEROL GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
PALBINONE GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
MANZAMINE A GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16872140

Sources:
DTC
TIDEGLUSIB GSK3B

Interaction Score: 2.69

Interaction Types & Directionality:

antagonist (inhibitory)

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Glycogen synthase kinase-3 beta inhibitor

Trial Name tideglusib, NP-12,Nypta

PMIDs:
21760986

Sources:
TdgClinicalTrial ChemblInteractions TTD
CHEMBL259850 GSK3B

Interaction Score: 1.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423 10592235

Sources:
DTC TTD
SR-13668 GSK3B

Interaction Score: 0.9

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17602463

Sources:
DTC
OLEANOLIC_ACID GSK3B

Interaction Score: 0.9

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
BETULINIC ACID GSK3B

Interaction Score: 0.67

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
LITHIUM CITRATE GSK3B

Interaction Score: 0.45

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
LITHIUM CARBONATE GSK3B

Interaction Score: 0.45

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

PMIDs:
None found

Sources:
ChemblInteractions
SB-216763 GSK3B

Interaction Score: 0.41

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20030405 25467150 20708937

Sources:
DTC
CHEMBL588859 GSK3B

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL1276446 GSK3B

Interaction Score: 0.34

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CEP-11981 GSK3B

Interaction Score: 0.24

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22148921

Sources:
DTC
CHIR-99021 GSK3B

Interaction Score: 0.24

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
DTC TTD
LITHIUM GSK3B

Interaction Score: 0.23

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
16733521 17628506 19754466 24885933 23021822 21781277 21047205

Sources:
PharmGKB
URSOLIC ACID GSK3B

Interaction Score: 0.22

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
19716700

Sources:
DTC
AZD-1080 GSK3B

Interaction Score: 0.16

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
DTC ChemblInteractions
AZAKENPAULLONE GSK3B

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
AT-9283 GSK3B

Interaction Score: 0.12

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

PMIDs:
None found

Sources:
TALC
ALSTERPAULLONE GSK3B

Interaction Score: 0.11

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
10592235 17016423 17139284

Sources:
DTC
BMS-387032 GSK3B

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
LY-2090314 GSK3B

Interaction Score: 0.1

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Glycogen synthase kinase-3 beta inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
ChemblInteractions TTD
FLUOXETINE GSK3B

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18195729

Sources:
PharmGKB
CITALOPRAM GSK3B

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
18195729

Sources:
PharmGKB
CI-1040 GSK3B

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
TTD
KENPAULLONE GSK3B

Interaction Score: 0.06

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

PMIDs:
None found

Sources:
DTC TTD
SB-203580 GSK3B

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL546797 GSK3B

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL541400 GSK3B

Interaction Score: 0.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GW843682X GSK3B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GO-6976 GSK3B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL379975 GSK3B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GSK-269962A GSK3B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
JNJ-7706621 GSK3B

Interaction Score: 0.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SOTRASTAURIN GSK3B

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
GW441756X GSK3B

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CHEMBL225519 GSK3B

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RG-1530 GSK3B

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SP-600125 GSK3B

Interaction Score: 0.02

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CYC-116 GSK3B

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PF-00562271 GSK3B

Interaction Score: 0.01

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

Ensembl: ENSG00000082701
- Version: 101_38
Alternate Names:

GSK3B Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
TdgClinicalTrial: P49841
- Version: January-2014
Alternate Names:

GSK3B Gene Symbol

Gene Info:

Target Class Enzymes

Target Subclass EC:2.7.11.26

Publications:
RussLampel: ENSG00000082701
- Version: 26-July-2011
Alternate Names:

ENSG00000082701 Ensembl Gene Id

GLYCOGEN SYNTHASE KINASE-3 BETA (EC 2.7.1.37) (GSK-3 BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49841] Description

GSK3B Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
HopkinsGroom: P49841
- Version: 11-September-2012
Alternate Names:

P49841 Uniprot Accession

2932 Entrez Gene Id

GSK3B_HUMAN Uniprot Id

Gene Info:

Uniprot Status Swiss-Prot

Interpro Short Name Ser/Thr_dual-sp_kinase_dom

Human Readable Name DRUGGABLE GENOME

Gene Categories:

KINASE, DRUGGABLE GENOME

Publications:

PharmGKB: GSK3B

Version: 18-August-2020

Alternate Names:

PA29009 PharmGKB ID

Gene Info:

Publications:

Tsai SJ et al., 2008, Glycogen synthase kinase-3beta gene is associated with antidepressant treatment response in Chinese major depressive disorder., Pharmacogenomics J

McCarthy MJ et al., 2011, Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder., Genes Brain Behav

Lin YF et al., 2013, Glycogen synthase kinase 3β gene polymorphisms may be associated with bipolar I disorder and the therapeutic response to lithium., J Affect Disord

DTC: GSK3B

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Rao KV et al., 2006, Manzamine B and E and ircinal A related alkaloids from an Indonesian Acanthostrongylophora sponge and their activity against infectious, tropical parasitic, and Alzheimer's diseases., J Nat Prod

Ha do T et al., 2009, Palbinone and triterpenes from Moutan Cortex (Paeonia suffruticosa, Paeoniaceae) stimulate glucose uptake and glycogen synthesis via activation of AMPK in insulin-resistant human HepG2 Cells., Bioorg Med Chem Lett

Chao WR et al., 2007, Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling., J Med Chem

TALC: GSK3B
- Version: 12-May-2016
Alternate Names:

GSK3B Gene Symbol

Gene Info:

Publications:
ChemblInteractions: GSK3B
- Version: chembl_23
Alternate Names:

GSK3B GENE_SYMBOL

Glycogen synthase kinase-3 beta UNIPROT

Serine/threonine-protein kinase GSK3B UNIPROT

Gene Info:

Publications:
HingoraniCasas: ENSG00000082701
- Version: 31-May-2017
Alternate Names:

ENSG00000082701 Gene Symbol

GSK3B Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
dGene: GSK3B
- Version: 27-Jun-2013
Alternate Names:

2932 Gene ID

- dGene Synonym

Gene Info:

Gene Categories:

KINASE, SERINE THREONINE KINASE

Publications:
TTD: Glycogen synthase kinase-3 beta
- Version: 2020.06.01
Alternate Names:

GSK-3B TTD Gene Abbreviation

T70977 TTD Target ID

Gene Info:

Publications:
Pharos: GSK3B
- Version: 01-February-2022
Alternate Names:

Glycogen synthase kinase-3 beta Gene Name

P49841 UniProt ID

Gene Info:

Gene Categories:

KINASE, TRANSCRIPTION FACTOR

Publications:
MskImpact: GSK3B
- Version: May-2015
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
FoundationOneGenes: GSK3B
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
CarisMolecularIntelligence: GSK3B
- Version: 04-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
GO: GSK3B
- Version: 01-February-2022
Alternate Names:

Gene Info:

Gene Categories:

KINASE, SERINE THREONINE KINASE

Publications:

Direct Interaction	yes
Mechanism of Interaction	Glycogen synthase kinase-3 beta inhibitor
Trial Name	tideglusib, NP-12,Nypta

Direct Interaction	yes
Mechanism of Interaction	Glycogen synthase kinase-3 inhibitor

ENSG00000082701	Ensembl Gene Id
GLYCOGEN SYNTHASE KINASE-3 BETA (EC 2.7.1.37) (GSK-3 BETA). [SOURCE:UNIPROT/SWISSPROT;ACC:P49841]	Description
GSK3B	Display Id

P49841	Uniprot Accession
2932	Entrez Gene Id
GSK3B_HUMAN	Uniprot Id

GSK3B	GENE_SYMBOL
Glycogen synthase kinase-3 beta	UNIPROT
Serine/threonine-protein kinase GSK3B	UNIPROT

antagonist (inhibitory)
inhibitor (inhibitory)

GSK3B Gene Record

GSK3B 2932 Druggable GenomeClinically Actionable

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19081248

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19716700

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19716700

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23354070

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19716700

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19716700

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16872140

Sources: DTC

Interaction Types & Directionality: antagonist (inhibitory) inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Glycogen synthase kinase-3 beta inhibitor Trial Name tideglusib, NP-12,Nypta

PMIDs: 21760986

Sources: TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423 10592235

Sources: DTC TTD

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17602463

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19716700

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 19716700

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info: Direct Interaction yes Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

PMIDs: None found

Sources: ChemblInteractions

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20030405 25467150 20708937

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22148921

Sources: DTC

Interaction Types & Directionality: inhibitor (inhibitory)

Interaction Info:

Interaction Types & Directionality:

n/a

PMIDs:
19081248

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
23354070

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
16872140

Sources:
DTC

Interaction Types & Directionality:

antagonist (inhibitory)

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Glycogen synthase kinase-3 beta inhibitor

Trial Name tideglusib, NP-12,Nypta

PMIDs:
21760986

Sources:
TdgClinicalTrial ChemblInteractions TTD

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423 10592235

Sources:
DTC TTD

Interaction Types & Directionality:

n/a

PMIDs:
17602463

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Direct Interaction yes

Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

PMIDs:
None found

Sources:
ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
20030405 25467150 20708937

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
22148921

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
None found

Sources:
DTC TTD

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
16733521 17628506 19754466 24885933 23021822 21781277 21047205

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
19716700

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Mechanism of Interaction Glycogen synthase kinase-3 inhibitor

Direct Interaction yes

PMIDs:
None found

Sources:
DTC ChemblInteractions

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

inhibitor (inhibitory)

Interaction Info:

Notes

PMIDs:
None found

Sources:
TALC

Interaction Types & Directionality:

inhibitor (inhibitory)

PMIDs:
10592235 17016423 17139284

Sources:
DTC