DGIdb - GRK5 Gene Record

GRK5 2869 Druggable Genome

Alternate Names:

2869
G PROTEIN-COUPLED RECEPTOR KINASE 5
GRK5
GPRK5
600870
4544
ENSG00000198873
OTTHUMG00000019149
P34947
PA180
GRK5_HUMAN
G PROTEIN-COUPLED RECEPTOR KINASE 5 (EC 2.7.1.-) (G PROTEIN-COUPLED RECEPTOR KINASE GRK5). [SOURCE:UNIPROT/SWISSPROT;ACC:P34947]
T69612
FP2025

Gene Info:

Human Readable Name	DRUGGABLE GENOME
Uniprot Status	Swiss-Prot
Uniprot Evidence	1: Evidence at protein level
Human Readable Name	KINASE
Interpro Short Name	Ser/Thr_dual-sp_kinase_dom
Interpro Acc	IPR002290
Interpro Name	Serine/threonine- / dual-specificity protein kinase, catalytic domain
Interpro Type	Domain
Gene Biotype	PROTEIN_CODING

(6 More Sources)

Gene Categories: Category Details

TUMOR SUPPRESSOR
KINASE
SERINE THREONINE KINASE
G PROTEIN COUPLED RECEPTOR
DRUGGABLE GENOME

Publications:

ESCITALOPRAM GRK5

Interaction Score: 0.31

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
MLN-8054 GRK5

Interaction Score: 0.21

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
CITALOPRAM GRK5

Interaction Score: 0.17

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
PharmGKB
CHEMBL1997335 GRK5

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ALISERTIB GRK5

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
JNJ-7706621 GRK5

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
SOTRASTAURIN GRK5

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
ENTRECTINIB GRK5

Interaction Score: 0.1

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
RG-1530 GRK5

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
TAE-684 GRK5

Interaction Score: 0.06

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
PF-00562271 GRK5

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC

Ensembl: ENSG00000198873
- Version: 101_38
Alternate Names:

GRK5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000198873

Version: 26-July-2011

Alternate Names:

GRK5 Display Id

ENSG00000198873 Ensembl Gene Id

G PROTEIN-COUPLED RECEPTOR KINASE 5 (EC 2.7.1.-) (G PROTEIN-COUPLED RECEPTOR KINASE GRK5). [SOURCE:UNIPROT/SWISSPROT;ACC:P34947] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:

HopkinsGroom: P34947
- Version: 11-September-2012
Alternate Names:

GRK5 Uniprot Gene Name

ENSG00000198873 Ensembl Gene Id

2869 Entrez Gene Id

Gene Info:

Uniprot Status Swiss-Prot

Uniprot Evidence 1: Evidence at protein level

Human Readable Name KINASE

Gene Categories:

KINASE, DRUGGABLE GENOME

Publications:

PharmGKB: GRK5

Version: 18-August-2020

Alternate Names:

PA180 PharmGKB ID

Gene Info:

Publications:

Liggett SB et al., 2008, A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure., Nat Med

Lobmeyer MT et al., 2011, Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients., Pharmacogenet Genomics

HingoraniCasas: ENSG00000198873
- Version: 31-May-2017
Alternate Names:

ENSG00000198873 Gene Symbol

GRK5 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: GRK5
- Version: 01-February-2022
Alternate Names:

GPRK5 GO Gene Synonym

Gene Info:

Gene Categories:

TUMOR SUPPRESSOR, SERINE THREONINE KINASE

Publications:
dGene: GRK5
- Version: 27-Jun-2013
Alternate Names:

2869 Gene ID

GPRK5 dGene Synonym

Gene Info:

Gene Categories:

KINASE, SERINE THREONINE KINASE

Publications:
TTD: G protein-coupled receptor kinase 5
- Version: 2020.06.01
Alternate Names:

GRK5 TTD Gene Abbreviation

T69612 TTD Target ID

Gene Info:

Publications:
Pharos: GRK5
- Version: 01-February-2022
Alternate Names:

G protein-coupled receptor kinase 5 Gene Name

P34947 UniProt ID

Gene Info:

Gene Categories:

KINASE, G PROTEIN COUPLED RECEPTOR

Publications:
DTC: GRK5
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

GRK5	Display Id
ENSG00000198873	Ensembl Gene Id
G PROTEIN-COUPLED RECEPTOR KINASE 5 (EC 2.7.1.-) (G PROTEIN-COUPLED RECEPTOR KINASE GRK5). [SOURCE:UNIPROT/SWISSPROT;ACC:P34947]	Description

GRK5	Uniprot Gene Name
ENSG00000198873	Ensembl Gene Id
2869	Entrez Gene Id

G protein-coupled receptor kinase 5	Gene Name
P34947	UniProt ID

GRK5 Gene Record

GRK5 2869 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Ensembl: ENSG00000198873

Alternate Names: GRK5 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000198873

Alternate Names: GRK5 Display Id ENSG00000198873 Ensembl Gene Id G PROTEIN-COUPLED RECEPTOR KINASE 5 (EC 2.7.1.-) (G PROTEIN-COUPLED RECEPTOR KINASE GRK5). [SOURCE:UNIPROT/SWISSPROT;ACC:P34947] Description

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

HopkinsGroom: P34947

Alternate Names: GRK5 Uniprot Gene Name ENSG00000198873 Ensembl Gene Id 2869 Entrez Gene Id

Gene Info: Uniprot Status Swiss-Prot Uniprot Evidence 1: Evidence at protein level Human Readable Name KINASE

Gene Categories: KINASE, DRUGGABLE GENOME

Publications:

PharmGKB: GRK5

Alternate Names: PA180 PharmGKB ID

Gene Info:

HingoraniCasas: ENSG00000198873

Alternate Names: ENSG00000198873 Gene Symbol GRK5 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

GO: GRK5

Alternate Names: GPRK5 GO Gene Synonym

Gene Info:

Gene Categories: TUMOR SUPPRESSOR, SERINE THREONINE KINASE

Publications:

dGene: GRK5

Alternate Names: 2869 Gene ID GPRK5 dGene Synonym

Gene Info:

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Alternate Names:

GRK5 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

GRK5 Display Id

ENSG00000198873 Ensembl Gene Id

G PROTEIN-COUPLED RECEPTOR KINASE 5 (EC 2.7.1.-) (G PROTEIN-COUPLED RECEPTOR KINASE GRK5). [SOURCE:UNIPROT/SWISSPROT;ACC:P34947] Description

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

GRK5 Uniprot Gene Name

ENSG00000198873 Ensembl Gene Id

2869 Entrez Gene Id

Gene Info:

Uniprot Status Swiss-Prot

Uniprot Evidence 1: Evidence at protein level

Human Readable Name KINASE

Gene Categories:

KINASE, DRUGGABLE GENOME

Alternate Names:

PA180 PharmGKB ID

Alternate Names:

ENSG00000198873 Gene Symbol

GRK5 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

GPRK5 GO Gene Synonym

Gene Categories:

TUMOR SUPPRESSOR, SERINE THREONINE KINASE

Alternate Names:

2869 Gene ID

GPRK5 dGene Synonym

Gene Categories:

KINASE, SERINE THREONINE KINASE

Alternate Names:

GRK5 TTD Gene Abbreviation

T69612 TTD Target ID

Alternate Names:

G protein-coupled receptor kinase 5 Gene Name

P34947 UniProt ID

Gene Categories:

KINASE, G PROTEIN COUPLED RECEPTOR