• Interaction Score: 2.71

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Full agonist

    PMIDs:
    None found


  • Interaction Score: 1.62

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
    Direct Interaction yes
    Trial Name tezampanel, NGX424,NGX426

    PMIDs:
    None found


  • Interaction Score: 1.35

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:


    Sources:
    DrugBank

  • Interaction Score: 1.01

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.52

    Interaction Types & Directionality:
    n/a

    Interaction Info:


    Sources:
    DrugBank

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27023437


    Sources:
    PharmGKB

  • Interaction Score: 0.18

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Glutamate receptor ionotropic kainate antagonist

    PMIDs:
    None found