• GPR68 8111 Druggable Genome

    Alternate Names:

    8111
    G PROTEIN-COUPLED RECEPTOR 68
    GPR68
    AI2A6
    GPR12A
    OGR1
    601404
    4519
    ENSG00000119714
    OTTHUMG00000167590
    Q15743
    OGR1_HUMAN
    OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1
    114
    <i>GPR68</i>
    SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR (OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1) (OGR-1) (G-PROTEIN COUPLED RECEPTOR 68) (GPR12A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15743]
    NM_003485
    NP_003476

    Gene Info:

    Interpro Name GPCR, rhodopsin-like, 7TM
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Acc IPR000276
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Family
    Gene Biotype PROTEIN_CODING
    GuideToPharmacology Gene Category Name Class A Orphans
    GuideToPharmacology Gene Category ID 16
    (5 More Sources)

    Gene Categories: Category Details

    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME

    Publications:

  • Interaction Score: 2.47

    Interaction Types & Directionality:
    allosteric modulator

    Interaction Info:
    Specific Action of the Ligand Positive
    Details of Interaction lorazepam characterised as a non-selective GPR68 positive allosteric modulator for the agonist proton in cAMP production
    Endogenous Drug? False

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    GPR68 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    GPR68 Uniprot Gene Name
    8111 Entrez Gene Id
    Q15743 Uniprot Accession

    Gene Info:
    Interpro Name GPCR, rhodopsin-like, 7TM
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    GPR68 Display Id
    SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR (OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1) (OGR-1) (G-PROTEIN COUPLED RECEPTOR 68) (GPR12A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15743] Description
    ENSG00000119714 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    4519 HUGO Gene ID
    4519 HUGO Gene Symbol
    G protein-coupled receptor 68 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Class A Orphans
    GuideToPharmacology Gene Category ID 16

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000119714 Gene Symbol
    GPR68 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 15-July-2019

    Alternate Names:
    GPR68 Gene Symbol

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000119714 Ensembl Gene ID
    OGR1 Human Protein Atlas Gene Synonym
    G protein-coupled receptor 68 Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 05-September-2020

    Alternate Names:
    OGR1 GO Gene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    8111 Gene ID
    GPR12A dGene Synonym
    OGR1 dGene Synonym

    Gene Info:

    Gene Categories:
    G PROTEIN COUPLED RECEPTOR

    Publications: