• Interaction Score: 4.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type uveal melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell line xenograft

    PMIDs:
    27308390


    Sources:
    JAX-CKB

  • Interaction Score: 1.75

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Evidence Type Actionable
    Approval Status Preclinical - Cell culture
    Response Type sensitive

  • Interaction Score: 1.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AEB071 + CGM097
    Indication/Tumor Type uveal melanoma
    Response Type predicted – sensitive

    PMIDs:
    27507190


    Sources:
    JAX-CKB

  • Interaction Score: 1.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type ocular melanoma
    Response Type predicted – sensitive
    Approval Status Phase I

    PMIDs:
    23434733


    Sources:
    JAX-CKB

  • Interaction Score: 1.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type uveal melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    22515704


    Sources:
    JAX-CKB

  • Interaction Score: 0.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    24504448


    Sources:
    CIViC

  • Interaction Score: 0.79

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AEB071 + PD-0325901
    Indication/Tumor Type uveal melanoma
    Response Type sensitive

    PMIDs:
    24141786


    Sources:
    JAX-CKB

  • Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Indication/Tumor Type uveal melanoma
    Response Type sensitive
    Approval Status Preclinical - Cell culture

    PMIDs:
    22253748


    Sources:
    JAX-CKB

  • Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy GSK2126458 + Trametinib
    Indication/Tumor Type uveal melanoma
    Response Type sensitive

    PMIDs:
    22733540


    Sources:
    JAX-CKB

  • Interaction Score: 0.4

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy MEK162 + AEB071
    Indication/Tumor Type uveal melanoma
    Response Type predicted – sensitive

    PMIDs:
    27507190


    Sources:
    JAX-CKB

  • Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AEB071 + CGM097
    Indication/Tumor Type uveal melanoma
    Response Type predicted – sensitive


    Sources:
    JAX-CKB

  • Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy AEB071 + Everolimus
    Indication/Tumor Type uveal melanoma
    Response Type predicted – sensitive

    PMIDs:
    27507190


    Sources:
    JAX-CKB

  • Interaction Score: 0.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy GSK2126458 + Trametinib
    Indication/Tumor Type uveal melanoma
    Response Type sensitive

    PMIDs:
    22733540


    Sources:
    JAX-CKB