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GAK Gene Record

  • Summary
  • Interactions
  • Claims
  • GAK 2580 Druggable Genome

    Alternate Names:

    2580
    CYCLIN G ASSOCIATED KINASE
    GAK
    DNAJ26
    DNAJC26
    602052
    4113
    ENSG00000178950
    OTTHUMG00000088301
    CYCLIN G-ASSOCIATED KINASE (EC 2.7.1.-). [SOURCE:UNIPROT/SWISSPROT;ACC:O14976]
    O14976
    Cyclin-G-associated kinase

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME

    Publications:

    Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.
  • CHEMBL261454   GAK

    Interaction Score: 15.46

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

  • SB-202190   GAK

    Interaction Score: 1.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22951114


    Sources:
    DTC

  • Ensembl: ENSG00000178950

    • Version: 101_38

    Alternate Names:
    GAK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000178950

    • Version: 26-July-2011

    Alternate Names:
    CYCLIN G-ASSOCIATED KINASE (EC 2.7.1.-). [SOURCE:UNIPROT/SWISSPROT;ACC:O14976] Description
    ENSG00000178950 Ensembl Gene Id
    GAK Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • DTC: GAK

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Selig R et al., 2012, A frozen analogue approach to aminopyridinylimidazoles leading to novel and promising p38 MAP kinase inhibitors., J Med Chem
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.

  • HingoraniCasas: ENSG00000178950

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000178950 Gene Symbol
    GAK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: GAK

    • Version: 27-Jun-2013

    Alternate Names:
    2580 Gene ID
    DNAJ26 dGene Synonym
    DNAJC26 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • Pharos: GAK

    • Version: 01-February-2022

    Alternate Names:
    Cyclin-G-associated kinase Gene Name
    O14976 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: GAK

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21