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EPHA2 1969 Druggable Genome
Alternate Names:
1969 EPH RECEPTOR A2 EPHA2 ARCC2 CTPA CTPP1 CTRCT6 ECK 176946 3386 ENSG00000142627 OTTHUMG00000009527 P29317 EPHA2_HUMAN EPHRIN TYPE-A RECEPTOR 2 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR ECK) (EPITHELIAL CELL KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P29317] Tyrosine-protein kinase receptor ECK Epithelial cell kinase Ephrin type-A receptor 2 T57278 Gene Info:
Target Subclass Kinase Target Subclass Eph Transmembrane Helix Count 1 Target Main Class Receptors Human Readable Name DRUGGABLE GENOME Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom Human Readable Name KINASE Interpro Acc IPR001245 Interpro Type Domain Uniprot Status Swiss-Prot Uniprot Evidence 1: Evidence at protein level Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain Target Class Receptors Target Subclass EC:2.7.10.1 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
CELL SURFACE KINASE TYROSINE KINASE DRUGGABLE GENOME Publications:
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Interaction Score: 7.27
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Interaction Types & Directionality:
antagonist (inhibitory) inhibitor (inhibitory) Interaction Info:
Clinical Status preclinical Pathway activation Variant Effect gain-of-function -
Interaction Score: 0.15
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Interaction Score: 0.13
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
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Interaction Score: 0.07
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Ephrin receptor inhibitor Direct Interaction yes -
Interaction Score: 0.05
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Interaction Score: 0.03
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Interaction Score: 0.03
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- Version: 101_38
Alternate Names:
EPHA2 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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Alternate Names:
ENSG00000142627 Ensembl Gene Id 1969 Entrez Gene Id P29317 Uniprot Accession Gene Info:
Target Subclass Kinase Target Subclass Eph Transmembrane Helix Count 1 Publications:
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- Version: January-2014
Alternate Names:
EPHA2 Gene Symbol Gene Info:
Target Class Receptors Target Subclass EC:2.7.10.1 Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000142627 Ensembl Gene Id EPHA2 Display Id EPHRIN TYPE-A RECEPTOR 2 PRECURSOR (EC 2.7.1.112) (TYROSINE-PROTEIN KINASE RECEPTOR ECK) (EPITHELIAL CELL KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:P29317] Description Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
EPHRIN TYPE-A RECEPTOR 2 Uniprot Protein Name EPHA2 Uniprot Gene Name ENSG00000142627 Ensembl Gene Id Gene Info:
Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom Human Readable Name DRUGGABLE GENOME Human Readable Name KINASE Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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Alternate Names:
Gene Info:
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- Version: 31-May-2017
Alternate Names:
ENSG00000142627 Gene Symbol EPHA2 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
ECK GENE_SYMBOL EPHA2 GENE_SYMBOL Ephrin type-A receptor 2 UNIPROT Gene Info:
Publications:
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Alternate Names:
ECK GO Gene Synonym Gene Info:
Gene Categories:
CELL SURFACE Publications:
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Alternate Names:
EPHA2 Gene Symbol Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
1969 Gene ID ARCC2 dGene Synonym CTPA dGene Synonym Gene Info:
Gene Categories:
KINASE, TYROSINE KINASE Publications:
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- Version: 2020.06.01
Alternate Names:
EPHA2 TTD Gene Abbreviation T57278 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Ephrin type-A receptor 2 Gene Name P29317 UniProt ID Gene Info:
Gene Categories:
KINASE Publications:
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- Version: 15-June-2013
Alternate Names:
Gene Info:
Publications:
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- Version: 30-February-2014
Alternate Names:
Gene Info:
Publications: