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ENOSF1 Gene Record

  • Summary
  • Interactions
  • Claims
  • ENOSF1 55556

    Alternate Names:

    55556
    ENOLASE SUPERFAMILY MEMBER 1
    ENOSF1
    RTS
    TYMSAS
    607427
    30365
    ENSG00000132199
    OTTHUMG00000131470
    PA134897613
    Mitochondrial enolase superfamily member 1
    Q7L5Y1

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Ruzzo A et al., 2008, Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy., Pharmacogenomics J
    Meulendijks D et al., 2017, Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies., Pharmacogenomics J
    Kim SR et al., 2010, Genetic polymorphisms associated with 5-Fluorouracil-induced neurotoxicity., Chemotherapy
    Yang YC et al., 2017, Association of thymidylate synthase polymorphisms with the tumor response to preoperative chemoradiotherapy in rectal cancer: a systematic review and meta-analysis., Pharmacogenomics J
    Gao J et al., 2013, Polymorphism of TS 3'-UTR predicts survival of Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel., Clin Transl Oncol
    James HM et al., 2008, Common polymorphisms in the folate pathway predict efficacy of combination regimens containing methotrexate and sulfasalazine in early rheumatoid arthritis., J Rheumatol
    Krajinovic M et al., 2005, Combining several polymorphisms of thymidylate synthase gene for pharmacogenetic analysis., Pharmacogenomics J
    Pellicer M et al., 2017, Identification of new SNPs associated with severe toxicity to capecitabine., Pharmacol Res
    Halvas et al., 2000, Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine., J. Virol.
    Miranda et al., 2005, The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations., Antimicrob. Agents Chemother.
  • CAPECITABINE   ENOSF1

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17549067 27995989 20714149 27001118 23263912 28347776


    Sources:
    PharmGKB

  • LAMIVUDINE   ENOSF1

    Interaction Score: 0.87

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10864683


    Sources:
    NCI

  • ZIDOVUDINE   ENOSF1

    Interaction Score: 0.71

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15980332


    Sources:
    NCI

  • FLUOROURACIL   ENOSF1

    Interaction Score: 0.65

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17549067 27995989 20714149 27001118 23263912


    Sources:
    PharmGKB

  • METHOTREXATE   ENOSF1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18322994 16130010


    Sources:
    PharmGKB

  • Ensembl: ENSG00000132199

    • Version: 101_38

    Alternate Names:
    ENOSF1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: ENOSF1

    • Version: 18-August-2020

    Alternate Names:
    PA134897613 PharmGKB ID

    Gene Info:

    Publications:
    Ruzzo A et al., 2008, Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy., Pharmacogenomics J
    Meulendijks D et al., 2017, Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies., Pharmacogenomics J
    Kim SR et al., 2010, Genetic polymorphisms associated with 5-Fluorouracil-induced neurotoxicity., Chemotherapy

  • NCI: ENOSF1

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Chong et al., 2002, Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach., Antivir. Chem. Chemother.
    Halvas et al., 2000, Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2',3'-dideoxy-3'-thiacytidine., J. Virol.
    Miranda et al., 2005, The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations., Antimicrob. Agents Chemother.

  • Pharos: ENOSF1

    • Version: 03-September-2020

    Alternate Names:
    Mitochondrial enolase superfamily member 1 Gene Name
    Q7L5Y1 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21