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ELANE 1991 Druggable Genome
Alternate Names:
1991 ELASTASE, NEUTROPHIL EXPRESSED ELANE ELA2 GE HLE HNE NE PMN-E SCN1 130130 3309 ENSG00000197561 OTTHUMG00000181839 P08246 2358 NEUTROPHIL ELASTASE NP_001963 NM_001972 ELNE_HUMAN LEUKOCYTE ELASTASE PRECURSOR (EC 3.4.21.37) (NEUTROPHIL ELASTASE) (PMN ELASTASE) (BONE MARROW SERINE PROTEASE) (MEDULLASIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P08246] T40332 Gene Info:
Target Class Enzymes Target Subclass EC:3.4.21.37 Human Readable Name PROTEASE GuideToPharmacology Gene Category Name S1: Chymotrypsin GuideToPharmacology Gene Category ID 751 Target Subclass 3.4.21.37 Target Main Class Enzymes Human Readable Name DRUGGABLE GENOME Interpro Name Peptidase S1/S6, chymotrypsin/Hap Interpro Short Name Peptidase_S1_S6 Interpro Acc IPR001254 Interpro Type Domain Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Gene Biotype PROTEIN_CODING Gene Categories: Category Details
CELL SURFACE PROTEASE DRUGGABLE GENOME ENZYME Publications:
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Interaction Score: 17.72
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
Interaction Score: 14.18
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Interaction Score: 14.18
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Interaction Score: 7.09
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Interaction Score: 7.09
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? True -
Interaction Score: 3.54
Interaction Types & Directionality:
n/a Interaction Info:
Trial Name erdosteine Novel drug target Established target -
Interaction Score: 3.54
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Interaction Score: 0.4
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- Version: 101_38
Alternate Names:
ELANE Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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Alternate Names:
ELA2 Gene Symbol P08246 Uniprot Accession ENSG00000197561 Ensembl Gene Id Gene Info:
Target Subclass 3.4.21.37 Target Main Class Enzymes Publications:
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- Version: January-2014
Alternate Names:
ELANE Gene Symbol ELA2 Gene Symbol Gene Info:
Target Class Enzymes Target Subclass EC:3.4.21.37 Publications:
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- Version: 26-July-2011
Alternate Names:
ELA2 Display Id LEUKOCYTE ELASTASE PRECURSOR (EC 3.4.21.37) (NEUTROPHIL ELASTASE) (PMN ELASTASE) (BONE MARROW SERINE PROTEASE) (MEDULLASIN). [SOURCE:UNIPROT/SWISSPROT;ACC:P08246] Description ENSG00000197561 Ensembl Gene Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: 11-September-2012
Alternate Names:
NEUTROPHIL ELASTASE Uniprot Protein Name ENSG00000197561 Ensembl Gene Id ELNE_HUMAN Uniprot Id Gene Info:
Interpro Name Peptidase S1/S6, chymotrypsin/Hap Interpro Short Name Peptidase_S1_S6 Interpro Acc IPR001254 Gene Categories:
PROTEASE, DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
3309 HUGO Gene ID 3309 HUGO Gene Symbol elastase, neutrophil expressed HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name S1: Chymotrypsin GuideToPharmacology Gene Category ID 751 Gene Categories:
ENZYME Publications:
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Alternate Names:
Gene Info:
Publications:
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Alternate Names:
Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000197561 Gene Symbol ELANE Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
1991 Gene ID ELA2 dGene Synonym GE dGene Synonym Gene Info:
Gene Categories:
PROTEASE Publications:
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- Version: 2020.06.01
Alternate Names:
NE TTD Gene Abbreviation T40332 TTD Target ID Gene Info:
Publications:
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Alternate Names:
ELA2 GO Gene Synonym Gene Info:
Gene Categories:
CELL SURFACE, PROTEASE Publications:
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Alternate Names:
Neutrophil elastase Gene Name P08246 UniProt ID Gene Info:
Gene Categories:
ENZYME Publications: