DGIdb - E2F1 Gene Record

E2F1 1869

Alternate Names:

1869
E2F TRANSCRIPTION FACTOR 1
E2F1
E2F-1
RBAP1
RBBP3
RBP3
189971
3113
ENSG00000101412
OTTHUMG00000032265
Q01094
T57059
Transcription factor E2F1

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

TUMOR SUPPRESSOR
TRANSCRIPTION FACTOR BINDING
TRANSCRIPTION FACTOR

Publications:

Salleh et al., 2004, Gene expression profiling of p53(+/-) knockout and wild-type mice following diethylstilbestrol administration., IUBMB Life
Gomez-Manzano et al., 2001, Adenovirally-mediated transfer of E2F-1 potentiates chemosensitivity of human glioma cells to temozolomide and BCNU., Int. J. Oncol.
Lee et al., 2006, Quercetin arrests G2/M phase and induces caspase-dependent cell death in U937 cells., Cancer Lett.
Fujita et al., 2002, Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cells., Am. J. Physiol. Heart Circ. Physiol.
Meng et al., 1999, p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin., Int. J. Oncol.
Rieber et al., 2003, N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression., Biochem. Pharmacol.
Banerjee et al., 1998, Role of E2F-1 in chemosensitivity., Cancer Res.
Russo et al., 2006, E2F-1 overexpression in U2OS cells increases cyclin B1 levels and cdc2 kinase activity and sensitizes cells to antimitotic agents., Cancer Res.
Martirosyan et al., 2004, Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model., Biochem. Pharmacol.
Dasgupta et al., 2006, Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin., Proc. Natl. Acad. Sci. U.S.A.
Tahara et al., 2004, Expression of thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase, E2F-1, Bak, Bcl-X, and Bcl-2, and clinical outcomes for gastric cancer patients treated with bolus 5-fluorouracil., Oncol. Rep.
Jung et al., 2001, Flavopiridol increases sensitization to gemcitabine in human gastrointestinal cancer cell lines and correlates with down-regulation of ribonucleotide reductase M2 subunit., Clin. Cancer Res.

PRIMAQUINE E2F1

Interaction Score: 0.71

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15450938

Sources:
NCI
CARMUSTINE E2F1

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11445852

Sources:
NCI
VASOPRESSIN E2F1

Interaction Score: 0.42

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12063292

Sources:
NCI
ADRIAMYCIN E2F1

Interaction Score: 0.37

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9863003

Sources:
NCI
ACETYLCYSTEINE E2F1

Interaction Score: 0.28

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
12754095

Sources:
NCI
DIETHYLSTILBESTROL E2F1

Interaction Score: 0.22

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15545218

Sources:
NCI
ETOPOSIDE E2F1

Interaction Score: 0.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9766655 16849574

Sources:
NCI
IRINOTECAN E2F1

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9766655

Sources:
NCI
NICOTINE E2F1

Interaction Score: 0.13

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16601104

Sources:
NCI
LARGAZOLE E2F1

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
None found

Sources:
DTC
BORTEZOMIB E2F1

Interaction Score: 0.08

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11489836

Sources:
NCI
PACLITAXEL E2F1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16849574

Sources:
NCI
FLUOROURACIL E2F1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9766655

Sources:
NCI
QUERCETIN E2F1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16274926

Sources:
NCI
METHOTREXATE E2F1

Interaction Score: 0.07

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
14654896

Sources:
NCI
CISPLATIN E2F1

Interaction Score: 0.05

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16849574

Sources:
NCI

Ensembl: ENSG00000101412
- Version: 101_38
Alternate Names:

E2F1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

NCI: E2F1

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Salleh et al., 2004, Gene expression profiling of p53(+/-) knockout and wild-type mice following diethylstilbestrol administration., IUBMB Life

Meng et al., 1999, p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin., Int. J. Oncol.

Banerjee et al., 1998, Role of E2F-1 in chemosensitivity., Cancer Res.

Pharos: E2F1
- Version: 03-September-2020
Alternate Names:

Transcription factor E2F1 Gene Name

Q01094 UniProt ID

Gene Info:

Gene Categories:

TRANSCRIPTION FACTOR

Publications:
GO: E2F1
- Version: 05-September-2020
Alternate Names:

RBBP3 GO Gene Synonym

Gene Info:

Gene Categories:

TUMOR SUPPRESSOR, TRANSCRIPTION FACTOR BINDING

Publications:
TTD: E2F transcription factor 1
- Version: 2020.06.01
Alternate Names:

E2F1 TTD Gene Abbreviation

T57059 TTD Target ID

Gene Info:

Publications:
DTC: E2F1
- Version: 02-September-2020
Alternate Names:

Gene Info:

Publications:

E2F1 Gene Record

E2F1 1869

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15450938

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11445852

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12063292

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9863003

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 12754095

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15545218

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9766655 16849574

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9766655

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16601104

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: None found

Sources: DTC

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11489836

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16849574

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9766655

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16274926

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 14654896

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16849574

Sources: NCI

Ensembl: ENSG00000101412

Alternate Names: E2F1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

NCI: E2F1

Alternate Names:

Gene Info:

Pharos: E2F1

Alternate Names: Transcription factor E2F1 Gene Name Q01094 UniProt ID

Gene Info:

Interaction Types & Directionality:

n/a

PMIDs:
15450938

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11445852

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12063292

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9863003

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
12754095

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
15545218

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9766655 16849574

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9766655

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16601104

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
None found

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
11489836

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16849574

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9766655

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16274926

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
14654896

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
16849574

Sources:
NCI

Alternate Names:

E2F1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

Transcription factor E2F1 Gene Name

Q01094 UniProt ID

Gene Categories:

TRANSCRIPTION FACTOR

Alternate Names:

RBBP3 GO Gene Synonym

Gene Categories:

TUMOR SUPPRESSOR, TRANSCRIPTION FACTOR BINDING

Alternate Names:

E2F1 TTD Gene Abbreviation

T57059 TTD Target ID