DYRK1B Gene Record

  • DYRK1B 9149 Druggable Genome

    Alternate Names:

    9149
    DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1B
    DYRK1B
    AOMS3
    MIRK
    604556
    3092
    ENSG00000105204
    OTTHUMG00000182584
    DYR1B_HUMAN
    Q9Y463
    DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B
    DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 1B (EC 2.7.1.37) (EC 2.7.1.112) (MIRK PROTEIN KINASE) (MINIBRAIN-RELATED KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y463]
    Dual-specificity tyrosine-phosphorylation regulated kinase 1B
    T82720

    Gene Info:

    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME
    Interpro Acc IPR002290
    Human Readable Name KINASE
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • LEUCETTAMINE B   DYRK1B

    Interaction Score: 1.61

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22998443


    Sources:
    DTC

  • HARMINE   DYRK1B

    Interaction Score: 0.75

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    22998443


    Sources:
    DTC

  • BMS-387032   DYRK1B

    Interaction Score: 0.43

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AZD-1080   DYRK1B

    Interaction Score: 0.33

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1997335   DYRK1B

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   DYRK1B

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PALBOCICLIB   DYRK1B

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   DYRK1B

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   DYRK1B

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   DYRK1B

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   DYRK1B

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000105204

    • Version: 101_38

    Alternate Names:
    DYRK1B Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000105204

    • Version: 26-July-2011

    Alternate Names:
    DYRK1B Display Id
    ENSG00000105204 Ensembl Gene Id
    DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION REGULATED KINASE 1B (EC 2.7.1.37) (EC 2.7.1.112) (MIRK PROTEIN KINASE) (MINIBRAIN-RELATED KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q9Y463] Description

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HopkinsGroom: Q9Y463

    • Version: 11-September-2012

    Alternate Names:
    Q9Y463 Uniprot Accession
    DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B Uniprot Protein Name
    DYRK1B Uniprot Gene Name

    Gene Info:
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • DTC: DYRK1B

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Tahtouh T et al., 2012, Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B., J Med Chem

  • HingoraniCasas: ENSG00000105204

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000105204 Gene Symbol
    DYRK1B Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • IDG: DYRK1B

    • Version: 15-July-2019

    Alternate Names:
    DYRK1B Gene Symbol

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • HumanProteinAtlas: DYRK1B

    • Version: 19.3

    Alternate Names:
    ENSG00000105204 Ensembl Gene ID
    MIRK Human Protein Atlas Gene Synonym
    Dual specificity tyrosine phosphorylation regulated kinase 1B Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • GO: DYRK1B

    • Version: 01-February-2022

    Alternate Names:
    MIRK GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE, TYROSINE KINASE

    Publications:

  • dGene: DYRK1B

    • Version: 27-Jun-2013

    Alternate Names:
    9149 Gene ID
    MIRK dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • TTD: Dual-specificity tyrosine-phosphorylation regulated kinase 1B

    • Version: 2020.06.01

    Alternate Names:
    DYRK1B TTD Gene Abbreviation
    T82720 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: DYRK1B

    • Version: 01-February-2022

    Alternate Names:
    Dual specificity tyrosine-phosphorylation-regulated kinase 1B Gene Name
    Q9Y463 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ENZYME

    Publications: