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DTYMK Gene Record

  • Summary
  • Interactions
  • Claims
  • DTYMK 1841

    Alternate Names:

    1841
    DEOXYTHYMIDYLATE KINASE
    DTYMK
    CDC8
    PP3731
    TMPK
    TYMK
    188345
    3061
    ENSG00000168393
    OTTHUMG00000133409
    PA150
    Thymidylate kinase
    P23919

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    KINASE

    Publications:

    de Angelis et al., 2004, Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil., Int. J. Oncol.
    Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics
    Lavie et al., 2004, Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase., Mini Rev Med Chem
    Prakash et al., 2002, Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line., Alcohol. Clin. Exp. Res.
  • STAVUDINE   DTYMK

    Interaction Score: 2.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15134538


    Sources:
    NCI

  • ZIDOVUDINE   DTYMK

    Interaction Score: 1.0

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22960662


    Sources:
    PharmGKB

  • ALCOHOL   DTYMK

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11923581


    Sources:
    NCI

  • FLUOROURACIL   DTYMK

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15067352


    Sources:
    NCI

  • Ensembl: ENSG00000168393

    • Version: 101_38

    Alternate Names:
    DTYMK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: DTYMK

    • Version: 18-August-2020

    Alternate Names:
    PA150 PharmGKB ID

    Gene Info:

    Publications:
    Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

  • NCI: DTYMK

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    de Angelis et al., 2004, Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil., Int. J. Oncol.
    Lavie et al., 2004, Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase., Mini Rev Med Chem
    Prakash et al., 2002, Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line., Alcohol. Clin. Exp. Res.

  • Pharos: DTYMK

    • Version: 01-February-2022

    Alternate Names:
    Thymidylate kinase Gene Name
    P23919 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21