DGIdb - DTYMK Gene Record

DTYMK 1841

Alternate Names:

1841
DEOXYTHYMIDYLATE KINASE
DTYMK
CDC8
PP3731
TMPK
TYMK
188345
3061
ENSG00000168393
OTTHUMG00000133409
P23919
BE0001221
PA150
Thymidylate kinase

Gene Info:

Gene Biotype	PROTEIN_CODING

(1 More Sources)

Gene Categories: Category Details

KINASE

Publications:

de Angelis et al., 2004, Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil., Int. J. Oncol.
Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics
Lavie et al., 2004, Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase., Mini Rev Med Chem
Prakash et al., 2002, Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line., Alcohol. Clin. Exp. Res.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

CHEMBL1160619 DTYMK

Interaction Score: 22.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
AZIDOTHYMIDINE MONOPHOSPHATE DTYMK

Interaction Score: 22.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL1236157 DTYMK

Interaction Score: 22.72

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL1229914 DTYMK

Interaction Score: 17.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423

Sources:
DrugBank
CHEMBL1160597 DTYMK

Interaction Score: 17.04

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423

Sources:
DrugBank
THYMIDINE MONOPHOSPHATE DTYMK

Interaction Score: 11.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
STAVUDINE DTYMK

Interaction Score: 0.81

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15134538

Sources:
NCI
ZIDOVUDINE DTYMK

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22960662

Sources:
PharmGKB
FLUOROURACIL DTYMK

Interaction Score: 0.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15067352

Sources:
NCI
ALCOHOL DTYMK

Interaction Score: 0.09

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11923581

Sources:
NCI

Ensembl: ENSG00000168393
- Version: 101_38
Alternate Names:

DTYMK Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
PharmGKB: DTYMK
- Version: 18-August-2020
Alternate Names:

PA150 PharmGKB ID

Gene Info:

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

DrugBank: BE0001221

Version: 5.1.7

Alternate Names:

DTYMK DrugBank Gene Name

P23919 UniProt Accession

1841 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: DTYMK

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

de Angelis et al., 2004, Molecular characterizations of derivatives of HCT116 colorectal cancer cells that are resistant to the chemotherapeutic agent 5-fluorouracil., Int. J. Oncol.

Lavie et al., 2004, Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase., Mini Rev Med Chem

Prakash et al., 2002, Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line., Alcohol. Clin. Exp. Res.

Pharos: DTYMK
- Version: 03-September-2020
Alternate Names:

Thymidylate kinase Gene Name

P23919 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:

DTYMK	DrugBank Gene Name
P23919	UniProt Accession
1841	Entrez Gene Id

DTYMK Gene Record

DTYMK 1841

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15134538

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22960662

Sources: PharmGKB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15067352

Sources: NCI

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11923581

Sources: NCI

Ensembl: ENSG00000168393

Alternate Names: DTYMK Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: DTYMK

Alternate Names: PA150 PharmGKB ID

Gene Info:

Publications: Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

DrugBank: BE0001221

Alternate Names: DTYMK DrugBank Gene Name P23919 UniProt Accession 1841 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: DTYMK

Alternate Names:

Gene Info:

Pharos: DTYMK

Alternate Names: Thymidylate kinase Gene Name P23919 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
15134538

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
22960662

Sources:
PharmGKB

Interaction Types & Directionality:

n/a

PMIDs:
15067352

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11923581

Sources:
NCI

Alternate Names:

DTYMK Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PA150 PharmGKB ID

Publications:

Ghodke Y et al., 2012, PharmGKB summary: zidovudine pathway., Pharmacogenet Genomics

Alternate Names:

DTYMK DrugBank Gene Name

P23919 UniProt Accession

1841 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

Thymidylate kinase Gene Name

P23919 UniProt ID

Gene Categories:

KINASE