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DLG4 Gene Record

  • Summary
  • Interactions
  • Claims
  • DLG4 1742

    Alternate Names:

    1742
    DISCS LARGE MAGUK SCAFFOLD PROTEIN 4
    DLG4
    PSD95
    SAP-90
    SAP90
    602887
    2903
    ENSG00000132535
    OTTHUMG00000134327
    P78352
    BE0004524
    Presynaptic density protein 95
    T04507
    Disks large homolog 4

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (2 More Sources)

    Gene Categories: Category Details

    CELL SURFACE
    KINASE
    ION CHANNEL

    Publications:

    Nash et al., 2005, Subcellular redistribution of the synapse-associated proteins PSD-95 and SAP97 in animal models of Parkinson's disease and L-DOPA-induced dyskinesia., FASEB J.
    de Bartolomeis et al., 2002, Acute administration of antipsychotics modulates Homer striatal gene expression differentially., Brain Res. Mol. Brain Res.
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
  • GUANIDINE   DLG4

    Interaction Score: 14.2

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • CHEMBL283807   DLG4

    Interaction Score: 8.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235 17139284 17016423


    Sources:
    DrugBank

  • LEVODOPA   DLG4

    Interaction Score: 0.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15703272


    Sources:
    NCI

  • HALOPERIDOL   DLG4

    Interaction Score: 0.36

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11834303


    Sources:
    NCI

  • Ensembl: ENSG00000132535

    • Version: 101_38

    Alternate Names:
    DLG4 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DrugBank: BE0004524

    • Version: 5.1.7

    Alternate Names:
    DLG4 DrugBank Gene Name
    P78352 UniProt Accession
    1742 Entrez Gene Id

    Gene Info:

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

  • NCI: DLG4

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Nash et al., 2005, Subcellular redistribution of the synapse-associated proteins PSD-95 and SAP97 in animal models of Parkinson's disease and L-DOPA-induced dyskinesia., FASEB J.
    Liaw et al., 2004, Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats., Neuroscience
    de Bartolomeis et al., 2002, Acute administration of antipsychotics modulates Homer striatal gene expression differentially., Brain Res. Mol. Brain Res.

  • Pharos: DLG4

    • Version: 03-September-2020

    Alternate Names:
    Disks large homolog 4 Gene Name
    P78352 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ION CHANNEL

    Publications:

  • GO: DLG4

    • Version: 05-September-2020

    Alternate Names:
    PSD95 GO Gene Synonym

    Gene Info:

    Gene Categories:
    CELL SURFACE

    Publications:

  • TTD: Presynaptic density protein 95

    • Version: 2020.06.01

    Alternate Names:
    DLG4 TTD Gene Abbreviation
    T04507 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21