DGIdb - DLG4 Gene Record

DLG4 1742

Alternate Names:

1742
DISCS LARGE MAGUK SCAFFOLD PROTEIN 4
DLG4
PSD95
SAP-90
SAP90
602887
2903
ENSG00000132535
OTTHUMG00000134327
P78352
BE0004524
Presynaptic density protein 95
T04507
Disks large homolog 4

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

CELL SURFACE
KINASE
ION CHANNEL

Publications:

Nash et al., 2005, Subcellular redistribution of the synapse-associated proteins PSD-95 and SAP97 in animal models of Parkinson's disease and L-DOPA-induced dyskinesia., FASEB J.
de Bartolomeis et al., 2002, Acute administration of antipsychotics modulates Homer striatal gene expression differentially., Brain Res. Mol. Brain Res.
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

GUANIDINE DLG4

Interaction Score: 14.2

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
CHEMBL283807 DLG4

Interaction Score: 8.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank
LEVODOPA DLG4

Interaction Score: 0.77

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
15703272

Sources:
NCI
HALOPERIDOL DLG4

Interaction Score: 0.36

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
11834303

Sources:
NCI

Ensembl: ENSG00000132535
- Version: 101_38
Alternate Names:

DLG4 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0004524

Version: 5.1.7

Alternate Names:

DLG4 DrugBank Gene Name

P78352 UniProt Accession

1742 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: DLG4

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Nash et al., 2005, Subcellular redistribution of the synapse-associated proteins PSD-95 and SAP97 in animal models of Parkinson's disease and L-DOPA-induced dyskinesia., FASEB J.

Liaw et al., 2004, Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats., Neuroscience

de Bartolomeis et al., 2002, Acute administration of antipsychotics modulates Homer striatal gene expression differentially., Brain Res. Mol. Brain Res.

Pharos: DLG4
- Version: 03-September-2020
Alternate Names:

Disks large homolog 4 Gene Name

P78352 UniProt ID

Gene Info:

Gene Categories:

KINASE, ION CHANNEL

Publications:
GO: DLG4
- Version: 05-September-2020
Alternate Names:

PSD95 GO Gene Synonym

Gene Info:

Gene Categories:

CELL SURFACE

Publications:
TTD: Presynaptic density protein 95
- Version: 2020.06.01
Alternate Names:

DLG4 TTD Gene Abbreviation

T04507 TTD Target ID

Gene Info:

Publications:

DLG4	DrugBank Gene Name
P78352	UniProt Accession
1742	Entrez Gene Id

DLG4	TTD Gene Abbreviation
T04507	TTD Target ID

DLG4 Gene Record

DLG4 1742

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

GUANIDINE DLG4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

CHEMBL283807 DLG4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235 17139284 17016423

Sources: DrugBank

LEVODOPA DLG4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 15703272

Sources: NCI

HALOPERIDOL DLG4

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 11834303

Sources: NCI

Ensembl: ENSG00000132535

Alternate Names: DLG4 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0004524

Alternate Names: DLG4 DrugBank Gene Name P78352 UniProt Accession 1742 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

NCI: DLG4

Alternate Names:

Gene Info:

Pharos: DLG4

Alternate Names: Disks large homolog 4 Gene Name P78352 UniProt ID

Gene Info:

Gene Categories: KINASE, ION CHANNEL

Publications:

GO: DLG4

Alternate Names: PSD95 GO Gene Synonym

Gene Info:

Gene Categories: CELL SURFACE

Publications:

TTD: Presynaptic density protein 95

Alternate Names: DLG4 TTD Gene Abbreviation T04507 TTD Target ID

Gene Info:

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
15703272

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
11834303

Sources:
NCI

Alternate Names:

DLG4 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

DLG4 DrugBank Gene Name

P78352 UniProt Accession

1742 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

Alternate Names:

Disks large homolog 4 Gene Name

P78352 UniProt ID

Gene Categories:

KINASE, ION CHANNEL

Alternate Names:

PSD95 GO Gene Synonym

Gene Categories:

CELL SURFACE

Alternate Names:

DLG4 TTD Gene Abbreviation

T04507 TTD Target ID