DGIdb - DHFR2 Gene Record

DHFR2 200895 Druggable Genome

Alternate Names:

200895
DIHYDROFOLATE REDUCTASE 2
DHFR2
DHFRL1
DHFRP4
616588
27309
ENSG00000178700
OTTHUMG00000159014
BE0004001
Q86XF0
DYRL1_HUMAN
DIHYDROFOLATE REDUCTASE, MITOCHONDRIAL
Dihydrofolate reductase 2, mitochondrial

Gene Info:

Uniprot Status	Swiss-Prot
Uniprot Evidence	1: Evidence at protein level
Interpro Short Name	DHFR_dom
Interpro Type	Domain
Human Readable Name	DRUGGABLE GENOME
Interpro Name	Dihydrofolate reductase domain
Interpro Acc	IPR001796
Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

DRUGGABLE GENOME
ENZYME

Publications:

Sánchez-del-Campo L et al., 2009, Binding of natural and synthetic polyphenols to human dihydrofolate reductase., Int J Mol Sci
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

CHEMBL329985 DHFR2

Interaction Score: 18.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL83547 DHFR2

Interaction Score: 18.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL328827 DHFR2

Interaction Score: 18.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL318721 DHFR2

Interaction Score: 18.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
CHEMBL100239 DHFR2

Interaction Score: 18.94

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
EPIGALOCATECHIN GALLATE DHFR2

Interaction Score: 0.65

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
20054477

Sources:
DrugBank

Ensembl: ENSG00000178700
- Version: 101_38
Alternate Names:

DHFR2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
RussLampel: ENSG00000178700
- Version: 26-July-2011
Alternate Names:

ENSG00000178700 Ensembl Gene Id

DHFRL1 Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Publications:
HopkinsGroom: Q86XF0
- Version: 11-September-2012
Alternate Names:

ENSG00000178700 Ensembl Gene Id

DHFRL1 Uniprot Gene Name

200895 Entrez Gene Id

Gene Info:

Uniprot Status Swiss-Prot

Uniprot Evidence 1: Evidence at protein level

Interpro Short Name DHFR_dom

Gene Categories:

DRUGGABLE GENOME

Publications:

DrugBank: BE0004001

Version: 5.1.7

Alternate Names:

DHFRL1 DrugBank Gene Name

Q86XF0 UniProt Accession

200895 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Sánchez-del-Campo L et al., 2009, Binding of natural and synthetic polyphenols to human dihydrofolate reductase., Int J Mol Sci

HingoraniCasas: ENSG00000178700
- Version: 31-May-2017
Alternate Names:

ENSG00000178700 Gene Symbol

DHFRL1 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: DHFR2
- Version: 03-September-2020
Alternate Names:

Dihydrofolate reductase 2, mitochondrial Gene Name

Q86XF0 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:

ENSG00000178700	Ensembl Gene Id
DHFRL1	Uniprot Gene Name
200895	Entrez Gene Id

DHFRL1	DrugBank Gene Name
Q86XF0	UniProt Accession
200895	Entrez Gene Id

Dihydrofolate reductase 2, mitochondrial	Gene Name
Q86XF0	UniProt ID

DHFR2 Gene Record

DHFR2 200895 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

CHEMBL329985 DHFR2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

CHEMBL83547 DHFR2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

CHEMBL328827 DHFR2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

CHEMBL318721 DHFR2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

CHEMBL100239 DHFR2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

EPIGALOCATECHIN GALLATE DHFR2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 20054477

Sources: DrugBank

Ensembl: ENSG00000178700

Alternate Names: DHFR2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

RussLampel: ENSG00000178700

Alternate Names: ENSG00000178700 Ensembl Gene Id DHFRL1 Display Id

Gene Info: Human Readable Name DRUGGABLE GENOME

Gene Categories: DRUGGABLE GENOME

Publications:

HopkinsGroom: Q86XF0

Alternate Names: ENSG00000178700 Ensembl Gene Id DHFRL1 Uniprot Gene Name 200895 Entrez Gene Id

Gene Info: Uniprot Status Swiss-Prot Uniprot Evidence 1: Evidence at protein level Interpro Short Name DHFR_dom

Gene Categories: DRUGGABLE GENOME

Publications:

DrugBank: BE0004001

Alternate Names: DHFRL1 DrugBank Gene Name Q86XF0 UniProt Accession 200895 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Sánchez-del-Campo L et al., 2009, Binding of natural and synthetic polyphenols to human dihydrofolate reductase., Int J Mol Sci

HingoraniCasas: ENSG00000178700

Alternate Names: ENSG00000178700 Gene Symbol DHFRL1 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

Pharos: DHFR2

Alternate Names: Dihydrofolate reductase 2, mitochondrial Gene Name Q86XF0 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
20054477

Sources:
DrugBank

Alternate Names:

DHFR2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

ENSG00000178700 Ensembl Gene Id

DHFRL1 Display Id

Gene Info:

Human Readable Name DRUGGABLE GENOME

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

ENSG00000178700 Ensembl Gene Id

DHFRL1 Uniprot Gene Name

200895 Entrez Gene Id

Gene Info:

Uniprot Status Swiss-Prot

Uniprot Evidence 1: Evidence at protein level

Interpro Short Name DHFR_dom

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

DHFRL1 DrugBank Gene Name

Q86XF0 UniProt Accession

200895 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Sánchez-del-Campo L et al., 2009, Binding of natural and synthetic polyphenols to human dihydrofolate reductase., Int J Mol Sci

Alternate Names:

ENSG00000178700 Gene Symbol

DHFRL1 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

Dihydrofolate reductase 2, mitochondrial Gene Name

Q86XF0 UniProt ID

Gene Categories:

ENZYME