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DDR1 780 Druggable GenomeClinically Actionable
Alternate Names:
780 DISCOIDIN DOMAIN RECEPTOR TYROSINE KINASE 1 DDR1 CAK CD167 DDR EDDR1 HGK2 MCK10 NEP NTRK4 PTK3 PTK3A RTK6 TRKE 600408 2730 ENSG00000204580 OTTHUMG00000031236 Q08345 EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 DDR1_HUMAN ENSG00000137332 ENSG00000215522 ENSG00000234078 ENSG00000230456 1843 NM_001202521 NP_001945 ENSG00000137332; ENSG00000204580; ENSG00000215522; ENSG00000230456; ENSG00000234078 BE0001124 EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1 PRECURSOR (EC 2.7.1.112) (TYROSINE KINASE DDR) (DISCOIDIN RECEPTOR TYROSINE KINASE) (TYROSINE- PROTEIN KINASE CAK) (CELL ADHESION KINASE) (TRK E) (PROTEIN-TYROSINE KINASE RTK 6) (CD167A ANTIGEN) (HGK2). [SOURCE:UNIPR Epithelial discoidin domain receptor 1 T09185 Gene Info:
Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain Interpro Acc IPR001245 Interpro Type Domain Human Readable Name KINASE Uniprot Status Swiss-Prot Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom Target Class Receptors Target Subclass EC:2.7.10.1 GuideToPharmacology Gene Category Name Type XVI RTKs: DDR (collagen receptor) family GuideToPharmacology Gene Category ID 331 Target Subclass Kinase Transmembrane Helix Count 1 Target Main Class Receptors Gene Biotype PROTEIN_CODING Gene Categories: Category Details
KINASE TYROSINE KINASE DRUGGABLE GENOME CLINICALLY ACTIONABLE Publications:
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Interaction Types & Directionality:
antagonist (inhibitory) inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False
Sources:
TEND TdgClinicalTrial DrugBank GuideToPharmacology -
Interaction Score: 1.78
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Details of the Assay for Interaction Binding constant determined by KINOMEScan assay. Specific Action of the Ligand Inhibition Endogenous Drug? False -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.1
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- Version: 101_38
Alternate Names:
DDR1 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
DDR1_HUMAN Uniprot Id EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 Uniprot Protein Name 780 Entrez Gene Id Gene Info:
Uniprot Evidence 1: Evidence at protein level Human Readable Name DRUGGABLE GENOME Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
DDR1 Gene Symbol Gene Info:
Target Class Receptors Target Subclass EC:2.7.10.1 Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000137332 Ensembl Gene Id EPITHELIAL DISCOIDIN DOMAIN RECEPTOR 1 PRECURSOR (EC 2.7.1.112) (TYROSINE KINASE DDR) (DISCOIDIN RECEPTOR TYROSINE KINASE) (TYROSINE- PROTEIN KINASE CAK) (CELL ADHESION KINASE) (TRK E) (PROTEIN-TYROSINE KINASE RTK 6) (CD167A ANTIGEN) (HGK2). [SOURCE:UNIPR Description DDR1 Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
ENSG00000137332; ENSG00000204580; ENSG00000215522; ENSG00000230456; ENSG00000234078 Ensembl Gene Id Q08345 Uniprot Accession DDR1_HUMAN Uniprot Id Gene Info:
Target Subclass Kinase Transmembrane Helix Count 1 Target Main Class Receptors Publications:
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- Version: 29-September-2020
Alternate Names:
2730 HUGO Gene ID 2730 HUGO Gene Symbol discoidin domain receptor tyrosine kinase 1 HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Type XVI RTKs: DDR (collagen receptor) family GuideToPharmacology Gene Category ID 331 Publications:
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Alternate Names:
DDR1 DrugBank Gene Name Q08345 UniProt Accession 780 Entrez Gene Id Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000204580 Gene Symbol DDR1 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
Epithelial discoidin domain-containing receptor 1 Gene Name Q08345 UniProt ID Gene Info:
Gene Categories:
KINASE Publications:
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Alternate Names:
780 Gene ID CAK dGene Synonym CD167 dGene Synonym Gene Info:
Gene Categories:
KINASE, TYROSINE KINASE Publications:
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- Version: 2020.06.01
Alternate Names:
DDR1 TTD Gene Abbreviation T09185 TTD Target ID Gene Info:
Publications:
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- Version: 03-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: