DAPK3 Gene Record

  • DAPK3 1613 Druggable Genome

    Alternate Names:

    1613
    DEATH ASSOCIATED PROTEIN KINASE 3
    DAPK3
    DLK
    ZIP
    ZIPK
    603289
    2676
    ENSG00000167657
    OTTHUMG00000181825
    2004
    O43293
    NP_001339
    NM_001348
    death-associated protein kinase 3
    DAPK3_HUMAN
    DEATH-ASSOCIATED PROTEIN KINASE 3 (EC 2.7.1.37) (DAP KINASE 3) (DAP- LIKE KINASE) (DLK) (ZIP-KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:O43293]

    Gene Info:

    GuideToPharmacology Gene Category Name Death-associated kinase (DAPK) family
    GuideToPharmacology Gene Category ID 572
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Type Domain
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name KINASE
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • SILMITASERTIB   DAPK3

    Interaction Score: 0.56

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • PI-103   DAPK3

    Interaction Score: 0.17

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LAUROGUADINE   DAPK3

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL406845   DAPK3

    Interaction Score: 0.12

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • FASUDIL   DAPK3

    Interaction Score: 0.11

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • AST-487   DAPK3

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1997335   DAPK3

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GSK-269962A   DAPK3

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL379975   DAPK3

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SP-600125   DAPK3

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    23634759


    Sources:
    DTC

  • PALBOCICLIB   DAPK3

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • JNJ-7706621   DAPK3

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ENTRECTINIB   DAPK3

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   DAPK3

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • R-406   DAPK3

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   DAPK3

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   DAPK3

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   DAPK3

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   DAPK3

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000167657

    • Version: 101_38

    Alternate Names:
    DAPK3 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: O43293

    • Version: 11-September-2012

    Alternate Names:
    1613 Entrez Gene Id
    DAPK3_HUMAN Uniprot Id
    DAPK3 Uniprot Gene Name

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000167657

    • Version: 26-July-2011

    Alternate Names:
    DEATH-ASSOCIATED PROTEIN KINASE 3 (EC 2.7.1.37) (DAP KINASE 3) (DAP- LIKE KINASE) (DLK) (ZIP-KINASE). [SOURCE:UNIPROT/SWISSPROT;ACC:O43293] Description
    ENSG00000167657 Ensembl Gene Id
    DAPK3 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GuideToPharmacology: 1613

    • Version: 29-September-2020

    Alternate Names:
    2676 HUGO Gene ID
    2676 HUGO Gene Symbol
    death associated protein kinase 3 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Death-associated kinase (DAPK) family
    GuideToPharmacology Gene Category ID 572

    Gene Categories:
    ENZYME

    Publications:

  • DTC: DAPK3

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Kusakabe K et al., 2013, Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125)., J Med Chem

  • HingoraniCasas: ENSG00000167657

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000167657 Gene Symbol
    DAPK3 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: DAPK3

    • Version: 27-Jun-2013

    Alternate Names:
    1613 Gene ID
    ZIP dGene Synonym
    ZIPK dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • GO: DAPK3

    • Version: 01-May-2021

    Alternate Names:
    ZIPK GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • Pharos: DAPK3

    • Version: 01-May-2021

    Alternate Names:
    Death-associated protein kinase 3 Gene Name
    O43293 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications: