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CXCL2 Gene Record

  • Summary
  • Interactions
  • Claims
  • CXCL2 2920 Druggable Genome

    Alternate Names:

    2920
    C-X-C MOTIF CHEMOKINE LIGAND 2
    CXCL2
    CINC-2a
    GRO2
    GROb
    MGSA-b
    MIP-2a
    MIP2
    MIP2A
    SCYB2
    139110
    4603
    ENSG00000081041
    OTTHUMG00000160865
    C-X-C motif chemokine 2
    T96627

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME

    Publications:

    Seow et al., 2008, Expression of chemokine/cytokine genes and immune cell recruitment following the instillation of Mycobacterium bovis, bacillus Calmette-Guérin or Lactobacillus rhamnosus strain GG in the healthy murine bladder., Immunology
    Burdon et al., 2008, Migration across the sinusoidal endothelium regulates neutrophil mobilization in response to ELR + CXC chemokines., Br. J. Haematol.
    Xiao et al., 1999, Involvement of p38 MAPK and ERK/MAPK pathways in staurosporine-induced production of macrophage inflammatory protein-2 in rat peritoneal neutrophils., Biochim. Biophys. Acta
    Scortegagna et al., 2008, HIF-1alpha regulates epithelial inflammation by cell autonomous NFkappaB activation and paracrine stromal remodeling., Blood
    Bachoual et al., 2007, Biological effects of particles from the paris subway system., Chem. Res. Toxicol.
  • BATIMASTAT   CXCL2

    Interaction Score: 24.73

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18477053


    Sources:
    NCI

  • BCG VACCINE   CXCL2

    Interaction Score: 2.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18217952


    Sources:
    NCI

  • DEFEROXAMINE   CXCL2

    Interaction Score: 1.77

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    17883261


    Sources:
    NCI

  • ALTEPLASE   CXCL2

    Interaction Score: 1.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    18199827


    Sources:
    NCI

  • STAUROSPORINE   CXCL2

    Interaction Score: 0.92

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10354507


    Sources:
    NCI

  • Ensembl: ENSG00000081041

    • Version: 101_38

    Alternate Names:
    CXCL2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: CXCL2

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Seow et al., 2008, Expression of chemokine/cytokine genes and immune cell recruitment following the instillation of Mycobacterium bovis, bacillus Calmette-Guérin or Lactobacillus rhamnosus strain GG in the healthy murine bladder., Immunology
    Burdon et al., 2008, Migration across the sinusoidal endothelium regulates neutrophil mobilization in response to ELR + CXC chemokines., Br. J. Haematol.
    Xiao et al., 1999, Involvement of p38 MAPK and ERK/MAPK pathways in staurosporine-induced production of macrophage inflammatory protein-2 in rat peritoneal neutrophils., Biochim. Biophys. Acta

  • HingoraniCasas: ENSG00000081041

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000081041 Gene Symbol
    CXCL2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • TTD: C-X-C motif chemokine 2

    • Version: 2020.06.01

    Alternate Names:
    CXCL2 TTD Gene Abbreviation
    T96627 TTD Target ID

    Gene Info:

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21