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CSK Gene Record

  • Summary
  • Interactions
  • Claims
  • CSK 1445 Druggable Genome

    Alternate Names:

    1445
    C-TERMINAL SRC KINASE
    CSK
    124095
    2444
    ENSG00000103653
    OTTHUMG00000142814
    CSK_HUMAN
    P41240
    TYROSINE-PROTEIN KINASE CSK (EC 2.7.1.112) (C-SRC KINASE) (PROTEIN- TYROSINE KINASE CYL). [SOURCE:UNIPROT/SWISSPROT;ACC:P41240]
    TYROSINE-PROTEIN KINASE CSK
    PA26946
    Cancer stemness kinase
    T64721
    T08741
    -

    Gene Info:

    Initial Gene Query CSK
    Counted Citations from 1950-2000 748
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Type Domain
    Human Readable Name KINASE
    Interpro Acc IPR001245
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME

    Publications:

    Iniesta R et al., 2019, Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals., Hypertension
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.
  • HYDROCHLOROTHIAZIDE   CSK

    Interaction Score: 1.72

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    31327267


    Sources:
    PharmGKB

  • HESPERADIN   CSK

    Interaction Score: 0.77

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

  • Ensembl: ENSG00000103653

    • Version: 101_38

    Alternate Names:
    CSK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • RussLampel: ENSG00000103653

    • Version: 26-July-2011

    Alternate Names:
    TYROSINE-PROTEIN KINASE CSK (EC 2.7.1.112) (C-SRC KINASE) (PROTEIN- TYROSINE KINASE CYL). [SOURCE:UNIPROT/SWISSPROT;ACC:P41240] Description
    ENSG00000103653 Ensembl Gene Id
    CSK Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • BaderLabGenes: CSK

    • Version: February-2014

    Alternate Names:
    1445 Entrez Gene ID

    Gene Info:
    Initial Gene Query CSK
    Counted Citations from 1950-2000 748

    Gene Categories:
    KINASE

    Publications:

  • HopkinsGroom: P41240

    • Version: 11-September-2012

    Alternate Names:
    TYROSINE-PROTEIN KINASE CSK Uniprot Protein Name
    CSK_HUMAN Uniprot Id
    P41240 Uniprot Accession

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • PharmGKB: CSK

    • Version: 18-August-2020

    Alternate Names:
    PA26946 PharmGKB ID

    Gene Info:

    Publications:
    Iniesta R et al., 2019, Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals., Hypertension

  • DTC: CSK

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:
    Bamborough et al., 2008, Assessment of chemical coverage of kinome space and its implications for kinase drug discovery., J. Med. Chem.

  • HingoraniCasas: ENSG00000103653

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000103653 Gene Symbol
    CSK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • dGene: CSK

    • Version: 27-Jun-2013

    Alternate Names:
    1445 Gene ID
    - dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

  • TTD: Tyrosine-protein kinase CSK

    • Version: 2020.06.01

    Alternate Names:
    CSK TTD Gene Abbreviation
    T08741 TTD Target ID

    Gene Info:

    Publications:

  • TTD: Cancer stemness kinase

    • Version: 2020.06.01

    Alternate Names:
    CSK TTD Gene Abbreviation
    T64721 TTD Target ID

    Gene Info:

    Publications:

  • Pharos: CSK

    • Version: 01-February-2022

    Alternate Names:
    Tyrosine-protein kinase CSK Gene Name
    P41240 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • GO: CSK

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    TYROSINE KINASE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21