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CP Gene Record

  • Summary
  • Interactions
  • Claims
  • CP 1356 Druggable Genome

    Alternate Names:

    1356
    CERULOPLASMIN
    CP
    CP-2
    117700
    2295
    ENSG00000047457
    OTTHUMG00000159563
    P00450
    AB073614

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    DRUGGABLE GENOME
    ENZYME

    Publications:

    Hasinoff et al., 1993, The removal of metal ions from transferrin, ferritin and ceruloplasmin by the cardioprotective agent ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] and its hydrolysis product ADR-925., Agents Actions
    Vijayalekshmy et al., 1992, Role of antibiotics in lipid peroxidation., Indian J. Biochem. Biophys.
    Shiono et al., 2001, Iron accumulation in the liver of male patients with Wilson's disease., Am. J. Gastroenterol.
    Kang et al., 1996, Suppression of plasma estradiol and progesterone concentrations by buthionine sulfoximine in female rats., Biochem. Pharmacol.
    Ahn et al., 1997, Oxidations of vincristine catalyzed by peroxidase and ceruloplasmin., J. Nat. Prod.
    Sato et al., 1997, Nitric oxide generation from hydroxyurea via copper-catalyzed peroxidation and implications for pharmacological actions of hydroxyurea., Jpn. J. Cancer Res.
    Bui et al., 1995, Comparative effects of 6-week nicotine treatment on blood pressure and components of the antioxidant system in male spontaneously hypertensive (SHR) and normotensive Wistar Kyoto (WKY) rats., Toxicology
    Schreiber et al., 1980, Dopaminergic modulation of the adenohypophyseal reaction to oestradiol: interaction of perphenazine with the thyroid hormones., Physiol Bohemoslov
    DiSilvestro et al., 2005, Soy isoflavone supplementation elevates erythrocyte superoxide dismutase, but not plasma ceruloplasmin in postmenopausal breast cancer survivors., Breast Cancer Res. Treat.
    Sasikumar et al., 2000, Effect of abana an ayurvedic formulation, on lipid peroxidation in experimental myocardial infarction in rats., Indian J. Exp. Biol.
    Kendall et al., 1992, The effects of diethylstilbestrol, tamoxifen, and toremifene on estrogen-inducible hepatic proteins and estrogen receptor proteins in female rats., Toxicol. Appl. Pharmacol.
    Laurell et al., 1979, A comparison of plasma protein changes induced by danazol, pregnancy, and estrogens., J. Clin. Endocrinol. Metab.
    Damtew et al., 1993, IL-1 receptor antagonist affects the plasma protein response of Hep 3B cells to conditioned medium from lipopolysaccharide-stimulated monocytes., J. Immunol.
    Kábrt et al., 1982, Acute and chronic vitamin C deficiency in guinea-pigs: its effect on ceruloplasmin and cytochrome P 450 and b5 levels., Physiol Bohemoslov
  • ISOFLAVONE   CP

    Interaction Score: 2.94

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    15754123


    Sources:
    NCI

  • DEXRAZOXANE   CP

    Interaction Score: 1.47

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8285144


    Sources:
    NCI

  • PENICILLAMINE   CP

    Interaction Score: 1.26

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    11721763


    Sources:
    NCI

  • ANAKINRA   CP

    Interaction Score: 1.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7682588


    Sources:
    NCI

  • AMPICILLIN   CP

    Interaction Score: 0.8

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1427966


    Sources:
    NCI

  • HYDROXYUREA   CP

    Interaction Score: 0.63

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9473738


    Sources:
    NCI

  • DANAZOL   CP

    Interaction Score: 0.55

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    489712


    Sources:
    NCI

  • PROTOPORPHYRIN   CP

    Interaction Score: 0.35

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6214811


    Sources:
    NCI

  • ISOPROTERENOL   CP

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12557918


    Sources:
    NCI

  • DIETHYLSTILBESTROL   CP

    Interaction Score: 0.3

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    1533964


    Sources:
    NCI

  • ESTRADIOL   CP

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    6446099


    Sources:
    NCI

  • NICOTINE   CP

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    7740554


    Sources:
    NCI

  • VINCRISTINE   CP

    Interaction Score: 0.15

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    9392881


    Sources:
    NCI

  • PROGESTERONE   CP

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8619904


    Sources:
    NCI

  • Ensembl: ENSG00000047457

    • Version: 101_38

    Alternate Names:
    CP Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: CP

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Vijayalekshmy et al., 1992, Role of antibiotics in lipid peroxidation., Indian J. Biochem. Biophys.
    Schreiber et al., 1980, Dopaminergic modulation of the adenohypophyseal reaction to oestradiol: interaction of perphenazine with the thyroid hormones., Physiol Bohemoslov
    Kendall et al., 1992, The effects of diethylstilbestrol, tamoxifen, and toremifene on estrogen-inducible hepatic proteins and estrogen receptor proteins in female rats., Toxicol. Appl. Pharmacol.

  • HingoraniCasas: ENSG00000047457

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000047457 Gene Symbol
    CP Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HumanProteinAtlas: CP

    • Version: 19.3

    Alternate Names:
    P00450 UniProt ID
    ENSG00000047457 Ensembl Gene ID
    Ceruloplasmin Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21