• CDK10 8558 Druggable Genome

    Alternate Names:

    8558
    CYCLIN DEPENDENT KINASE 10
    CDK10
    PISSLRE
    603464
    1770
    ENSG00000185324
    OTTHUMG00000138049
    Q15131
    Cell division protein kinase 10
    Cyclin-dependent kinase 10
    Serine/threonine-protein kinase PISSLRE
    CELL DIVISION PROTEIN KINASE 10 (EC 2.7.1.37) (SERINE/THREONINE- PROTEIN KINASE PISSLRE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15131]
    1962
    NP_001092003
    NM_001098533
    CDK10_HUMAN
    ALSAS

    Gene Info:

    Target Class Enzymes
    Target Subclass EC:2.7.11.22
    Human Readable Name DRUGGABLE GENOME
    GuideToPharmacology Gene Category Name CDK10 subfamily
    GuideToPharmacology Gene Category ID 494
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Human Readable Name KINASE
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Gene Biotype PROTEIN_CODING
    (8 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    ENZYME
    TRANSCRIPTION FACTOR

    Publications:

  • Interaction Score: 0.71

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Trial Name flavopiridol, alvocidib, HMR-1275
    Novel drug target Novel Target

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.64

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Cyclin-dependent kinase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.64

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Cyclin-dependent kinase inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.61

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Cyclin-dependent kinase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.61

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction Cyclin-dependent kinase inhibitor

    PMIDs:
    None found


    • Version: 101_38

    Alternate Names:
    CDK10 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    CDK10 Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.11.22

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    CDK10_HUMAN Uniprot Id
    Q15131 Uniprot Accession
    ENSG00000185324 Ensembl Gene Id

    Gene Info:
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Interpro Acc IPR002290

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    CELL DIVISION PROTEIN KINASE 10 (EC 2.7.1.37) (SERINE/THREONINE- PROTEIN KINASE PISSLRE). [SOURCE:UNIPROT/SWISSPROT;ACC:Q15131] Description
    CDK10 Display Id
    ENSG00000185324 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1770 HUGO Gene ID
    1770 HUGO Gene Symbol
    cyclin dependent kinase 10 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name CDK10 subfamily
    GuideToPharmacology Gene Category ID 494

    Gene Categories:
    ENZYME

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000185324 Gene Symbol
    CDK10 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: chembl_23

    Alternate Names:
    CDK10 GENE_SYMBOL
    Cyclin-dependent kinase 10 UNIPROT
    Cell division protein kinase 10 UNIPROT

    Gene Info:

    Publications:

    • Version: 15-July-2019

    Alternate Names:
    CDK10 Gene Symbol

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000185324 Ensembl Gene ID
    PISSLRE Human Protein Atlas Gene Synonym
    Cyclin dependent kinase 10 Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    8558 Gene ID
    PISSLRE dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Cyclin-dependent kinase 10 Gene Name
    Q15131 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

    • Version: 01-May-2021

    Alternate Names:

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications: