920 |
CD4 MOLECULE |
CD4 |
CD4mut |
186940 |
1678 |
ENSG00000010610 |
OTTHUMG00000168514 |
T-cell surface glycoprotein CD4 |
T-cell surface antigen T4/Leu-3 |
CD_antigen=CD4 |
P01730 |
T10191 |
IMD79 |
OKT4D |
Target Class | Receptors |
Target Subclass | Receptor |
Target Subclass | T-cell surface receptor |
Gene Biotype | PROTEIN_CODING |
KINASE |
EXTERNAL SIDE OF PLASMA MEMBRANE |
DRUGGABLE GENOME |
agonist (activating) |
antibody (inhibitory) |
Trial Name | BT-061 |
Novel drug target | Established target |
Mechanism of Interaction | T-cell surface antigen CD4 agonist |
n/a |
Trial Name | zanolimumab, HuMax-CD4 |
Novel drug target | Established target |
Mechanism of Interaction | T-cell surface antigen CD4 other |
antibody (inhibitory) |
antagonist (inhibitory) |
inhibitor (inhibitory) |
Mechanism of Interaction | T-cell surface antigen CD4 inhibitor |
Direct Interaction | yes |
negative modulator (inhibitory) |
Mechanism of Interaction | T-cell surface antigen CD4 negative modulator |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | T-cell surface antigen CD4 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | T-cell surface antigen CD4 inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Mechanism of Interaction | T-cell surface antigen CD4 inhibitor |
Direct Interaction | yes |
negative modulator (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | T-cell surface antigen CD4 negative modulator |
CD4 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
CD4 | Gene Symbol |
Target Class | Receptors |
Target Subclass | Receptor |
Target Subclass | T-cell surface receptor |
ENSG00000010610 | Gene Symbol |
CD4 | Ensembl Id |
DRUGGABLE GENOME |
CD4 | GENE_SYMBOL |
T-cell surface glycoprotein CD4 | UNIPROT |
T-cell surface antigen T4/Leu-3 | UNIPROT |
CD4 | TTD Gene Abbreviation |
T10191 | TTD Target ID |
T-cell surface glycoprotein CD4 | Gene Name |
P01730 | UniProt ID |
KINASE |
EXTERNAL SIDE OF PLASMA MEMBRANE |