DGIdb - CCNA2 Gene Record

CCNA2 890 Druggable Genome

Alternate Names:

890
CYCLIN A2
CCNA2
CCN1
CCNA
123835
1578
ENSG00000145386
OTTHUMG00000133072
PA94
P20248
Cyclin-A2

Gene Info:

Gene Biotype	PROTEIN_CODING

(2 More Sources)

Gene Categories: Category Details

KINASE
DRUGGABLE GENOME

Publications:

Gao T et al., 2014, CCNA2 is a prognostic biomarker for ER+ breast cancer and tamoxifen resistance., PLoS One
Hinek et al., 1999, Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells., Acta Neuropathol.
Heathcote DA et al., 2010, A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration., J Med Chem
Choi et al., 1998, Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells., Int. J. Oncol.

SELICICLIB CCNA2

Interaction Score: 2.58

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
21080703

Sources:
DTC
SURAMIN CCNA2

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10208280

Sources:
NCI
GENISTEIN CCNA2

Interaction Score: 0.62

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9664138

Sources:
NCI
TAMOXIFEN CCNA2

Interaction Score: 0.53

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
24622579

Sources:
PharmGKB

Ensembl: ENSG00000145386
- Version: 101_38
Alternate Names:

CCNA2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
PharmGKB: CCNA2
- Version: 18-August-2020
Alternate Names:

PA94 PharmGKB ID

Gene Info:

Publications:

Gao T et al., 2014, CCNA2 is a prognostic biomarker for ER+ breast cancer and tamoxifen resistance., PLoS One

NCI: CCNA2

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Hinek et al., 1999, Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells., Acta Neuropathol.

Fuchimoto et al., 2001, Posttranscriptional regulation of cyclin A1 and cyclin A2 during mouse oocyte meiotic maturation and preimplantation development., Biol. Reprod.

Payraudeau et al., 1998, Cyclin A2 and c-myc mRNA expression in ethinyl estradiol induced liver proliferation., Mol. Cell. Endocrinol.

DTC: CCNA2

Version: 02-September-2020

Alternate Names:

Gene Info:

Publications:

Heathcote DA et al., 2010, A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration., J Med Chem

HingoraniCasas: ENSG00000145386
- Version: 31-May-2017
Alternate Names:

ENSG00000145386 Gene Symbol

CCNA2 Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
Pharos: CCNA2
- Version: 01-February-2022
Alternate Names:

Cyclin-A2 Gene Name

P20248 UniProt ID

Gene Info:

Gene Categories:

KINASE

Publications:

CCNA2 Gene Record

CCNA2 890 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

SELICICLIB CCNA2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 21080703

Sources: DTC

SURAMIN CCNA2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10208280

Sources: NCI

GENISTEIN CCNA2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9664138

Sources: NCI

TAMOXIFEN CCNA2

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 24622579

Sources: PharmGKB

Ensembl: ENSG00000145386

Alternate Names: CCNA2 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

PharmGKB: CCNA2

Alternate Names: PA94 PharmGKB ID

Gene Info:

Publications: Gao T et al., 2014, CCNA2 is a prognostic biomarker for ER+ breast cancer and tamoxifen resistance., PLoS One

NCI: CCNA2

Alternate Names:

Gene Info:

DTC: CCNA2

Alternate Names:

Gene Info:

Publications: Heathcote DA et al., 2010, A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration., J Med Chem

HingoraniCasas: ENSG00000145386

Alternate Names: ENSG00000145386 Gene Symbol CCNA2 Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

Pharos: CCNA2

Alternate Names: Cyclin-A2 Gene Name P20248 UniProt ID

Gene Info:

Gene Categories: KINASE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
21080703

Sources:
DTC

Interaction Types & Directionality:

n/a

PMIDs:
10208280

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
9664138

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
24622579

Sources:
PharmGKB

Alternate Names:

CCNA2 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

PA94 PharmGKB ID

Publications:

Gao T et al., 2014, CCNA2 is a prognostic biomarker for ER+ breast cancer and tamoxifen resistance., PLoS One

Publications:

Heathcote DA et al., 2010, A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration., J Med Chem

Alternate Names:

ENSG00000145386 Gene Symbol

CCNA2 Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

Cyclin-A2 Gene Name

P20248 UniProt ID

Gene Categories:

KINASE