• CATSPER2 117155 Druggable Genome

    Alternate Names:

    117155
    CATION CHANNEL SPERM ASSOCIATED 2
    CATSPER2
    607249
    18810
    ENSG00000166762
    OTTHUMG00000059902
    Q96P56
    CTSR2_HUMAN
    CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2
    389
    NP_742095|NP_742093|NP_473361
    NM_172095|NM_054020
    SPERM-ASSOCIATED CATION CHANNEL 2 ISOFORM 3 [SOURCE:REFSEQ_PEPTIDE;ACC:NP_742094]

    Gene Info:

    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom
    Human Readable Name DRUGGABLE GENOME
    Interpro Type Domain
    Uniprot Status Swiss-Prot
    Interpro Acc IPR005821
    Interpro Name Ion transport domain
    GuideToPharmacology Gene Category Name CatSper and Two-Pore channels
    GuideToPharmacology Gene Category ID 70
    Initial Gene Query CatSper2
    Counted Citations from 1950-2000 22
    Gene Biotype PROTEIN_CODING
    (5 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    KINASE
    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology, kinetic rapid mixing fluorometry; 2-3 µM shows the saturating efficacy.
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology.
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology and kinetic rapid mixing fluometry.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    Publications:

  • Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology.
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

    • Version: 101_38

    Alternate Names:
    CATSPER2 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: February-2014

    Alternate Names:
    117155 Entrez Gene ID

    Gene Info:
    Initial Gene Query CatSper2
    Counted Citations from 1950-2000 22

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    SPERM-ASSOCIATED CATION CHANNEL 2 ISOFORM 3 [SOURCE:REFSEQ_PEPTIDE;ACC:NP_742094] Description
    CATSPER2 Display Id
    ENSG00000166762 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    CATION CHANNEL SPERM-ASSOCIATED PROTEIN 2 Uniprot Protein Name
    ENSG00000166762 Ensembl Gene Id
    117155 Entrez Gene Id

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    18810 HUGO Gene ID
    18810 HUGO Gene Symbol
    cation channel sperm associated 2 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name CatSper and Two-Pore channels
    GuideToPharmacology Gene Category ID 70

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000166762 Gene Symbol
    CATSPER2 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 15-July-2019

    Alternate Names:
    CATSPER2 Gene Symbol

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000166762 Ensembl Gene ID
    Cation channel sperm associated 2 Human Protein Atlas Gene Description
    Q96P56 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Cation channel sperm-associated protein 2 Gene Name
    Q96P56 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, ION CHANNEL

    Publications: