• CATSPER1 117144 Druggable Genome

    Alternate Names:

    117144
    CATION CHANNEL SPERM ASSOCIATED 1
    CATSPER1
    CATSPER
    SPGF7
    606389
    17116
    ENSG00000175294
    OTTHUMG00000166668
    Q8NEC5
    CTSR1_HUMAN
    SPERM-ASSOCIATED CATION CHANNEL 1 [SOURCE:REFSEQ_PEPTIDE;ACC:NP_444282]
    388
    CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1
    NP_444282
    NM_053054

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Name Ion transport domain
    Uniprot Status Swiss-Prot
    Interpro Acc IPR005821
    Initial Gene Query CatSper1
    Counted Citations from 1950-2000 44
    GuideToPharmacology Gene Category Name CatSper and Two-Pore channels
    GuideToPharmacology Gene Category ID 70
    Gene Biotype PROTEIN_CODING
    (3 More Sources)

    Gene Categories: Category Details

    TRANSPORTER
    ION CHANNEL
    DRUGGABLE GENOME

    Publications:

  • Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology, kinetic rapid mixing fluorometry, 2-3 µM shows the saturating efficacy.
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types & Directionality:
    blocker (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    Publications:

  • Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

  • Interaction Types & Directionality:
    activator (activating)

    Interaction Info:
    Details of the Assay for Interaction Patch clamp electrophysiology
    Specific Action of the Ligand Full agonist
    Endogenous Drug? True

    Publications:

    • Version: 101_38

    Alternate Names:
    CATSPER1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    SPERM-ASSOCIATED CATION CHANNEL 1 [SOURCE:REFSEQ_PEPTIDE;ACC:NP_444282] Description
    ENSG00000175294 Ensembl Gene Id
    CATSPER1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: February-2014

    Alternate Names:
    117144 Entrez Gene ID

    Gene Info:
    Initial Gene Query CatSper1
    Counted Citations from 1950-2000 44

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    CATSPER1 Uniprot Gene Name
    117144 Entrez Gene Id
    Q8NEC5 Uniprot Accession

    Gene Info:
    Human Readable Name ION CHANNEL
    Interpro Short Name Ion_trans_dom
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    ION CHANNEL, DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    17116 HUGO Gene ID
    17116 HUGO Gene Symbol
    cation channel sperm associated 1 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name CatSper and Two-Pore channels
    GuideToPharmacology Gene Category ID 70

    Gene Categories:
    ION CHANNEL

    Publications:

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000175294 Gene Symbol
    CATSPER1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 03-September-2020

    Alternate Names:
    Cation channel sperm-associated protein 1 Gene Name
    Q8NEC5 UniProt ID

    Gene Info:

    Gene Categories:
    ION CHANNEL

    Publications: