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CAST Gene Record

  • Summary
  • Interactions
  • Claims
  • CAST 831

    Alternate Names:

    831
    CALPASTATIN
    CAST
    BS-17
    PLACK
    114090
    1515
    ENSG00000153113
    OTTHUMG00000128413

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    PROTEASE INHIBITOR

    Publications:

    Neumar et al., 2003, Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis., J. Biol. Chem.
    Puliyanda et al., 2003, Calpain-mediated AQP2 proteolysis in inner medullary collecting duct., Biochem. Biophys. Res. Commun.
    Ariyoshi et al., 1993, Translocation of human platelet calpain-I., Biochem. Mol. Biol. Int.
    Ertbjerg et al., 2000, Epinephrine upregulates calpain activity in cultured C2C12 muscle cells., Biochimie
  • ANDROSTANOLONE   CAST

    Interaction Score: 1.34

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12646165


    Sources:
    NCI

  • THROMBIN   CAST

    Interaction Score: 1.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    8358337


    Sources:
    NCI

  • STAUROSPORINE   CAST

    Interaction Score: 1.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    12576481


    Sources:
    NCI

  • EPINEPHRINE   CAST

    Interaction Score: 1.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10863002


    Sources:
    NCI

  • Ensembl: ENSG00000153113

    • Version: 101_38

    Alternate Names:
    CAST Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • NCI: CAST

    • Version: 14-September-2017

    Alternate Names:

    Gene Info:

    Publications:
    Ertbjerg et al., 2000, Epinephrine upregulates calpain activity in cultured C2C12 muscle cells., Biochimie
    Sandmann et al., 2001, Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor., Br. J. Pharmacol.
    Grill et al., 2003, Tetracycline-inducible system for regulation of skeletal muscle-specific gene expression in transgenic mice., Transgenic Res.

  • dGene: CAST

    • Version: 27-Jun-2013

    Alternate Names:
    831 Gene ID
    BS-17 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE INHIBITOR

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21