CASP6 Gene Record

  • CASP6 839 Druggable Genome

    Alternate Names:

    839
    CASPASE 6
    CASP6
    MCH2
    601532
    1507
    ENSG00000138794
    OTTHUMG00000131914
    P55212
    CASPASE-6 PRECURSOR (EC 3.4.22.-) (CASP-6) (APOPTOTIC PROTEASE MCH-2). [SOURCE:UNIPROT/SWISSPROT;ACC:P55212]
    CASP-6
    Apoptotic protease Mch-2
    Caspase-6 subunit p11
    Caspase-6 subunit p18
    Caspase-6
    CASP6_HUMAN

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Human Readable Name PROTEASE
    Interpro Acc IPR002398
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Family
    Interpro Name Peptidase C14, caspase precursor p45
    Interpro Short Name Pept_C14_p45
    Uniprot Status Swiss-Prot
    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    PROTEASE
    DRUGGABLE GENOME
    ENZYME

    Publications:

  • METHYLERGONOVINE MALEATE   CASP6

    Interaction Score: 0.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1370674   CASP6

    Interaction Score: 0.76

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL176599   CASP6

    Interaction Score: 0.57

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL478754   CASP6

    Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALOSETRON HYDROCHLORIDE   CASP6

    Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ROEMERINE   CASP6

    Interaction Score: 0.46

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL445304   CASP6

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GAMOLENIC ACID   CASP6

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PAPAVERINE HYDROCHLORIDE   CASP6

    Interaction Score: 0.38

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL179611   CASP6

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL591137   CASP6

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1210769   CASP6

    Interaction Score: 0.29

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL139935   CASP6

    Interaction Score: 0.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL258756   CASP6

    Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • EMRICASAN   CASP6

    Interaction Score: 0.19

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction Caspase inhibitor
    Direct Interaction yes

    PMIDs:
    None found


    Sources:
    ChemblInteractions

  • NITROXOLINE   CASP6

    Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • EUPAFOLIN   CASP6

    Interaction Score: 0.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • STICTIC ACID   CASP6

    Interaction Score: 0.13

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL1601846   CASP6

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL515505   CASP6

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • THIMEROSAL   CASP6

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLTHIONINIUM CHLORIDE   CASP6

    Interaction Score: 0.1

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PYROGALLOL RED   CASP6

    Interaction Score: 0.09

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • METHYLDOPA   CASP6

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL505670   CASP6

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PURPUROGALLIN   CASP6

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • MYRICETIN   CASP6

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000138794

    • Version: 101_38

    Alternate Names:
    CASP6 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: P55212

    • Version: 11-September-2012

    Alternate Names:
    ENSG00000138794 Ensembl Gene Id
    CASP6 Uniprot Gene Name
    CASP6_HUMAN Uniprot Id

    Gene Info:
    Interpro Acc IPR002398
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level

    Gene Categories:
    PROTEASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000138794

    • Version: 26-July-2011

    Alternate Names:
    CASPASE-6 PRECURSOR (EC 3.4.22.-) (CASP-6) (APOPTOTIC PROTEASE MCH-2). [SOURCE:UNIPROT/SWISSPROT;ACC:P55212] Description
    ENSG00000138794 Ensembl Gene Id
    CASP6 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • HingoraniCasas: ENSG00000138794

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000138794 Gene Symbol
    CASP6 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • ChemblInteractions: MCH2

    • Version: chembl_23

    Alternate Names:
    MCH2 GENE_SYMBOL
    CASP6 GENE_SYMBOL
    Caspase-6 UNIPROT

    Gene Info:

    Publications:

  • dGene: CASP6

    • Version: 27-Jun-2013

    Alternate Names:
    839 Gene ID
    MCH2 dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • Pharos: CASP6

    • Version: 01-February-2022

    Alternate Names:
    Caspase-6 Gene Name
    P55212 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • DTC: CASP6

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications: