DGIdb - C1QB Gene Record

C1QB 713 Druggable Genome

Alternate Names:

713
COMPLEMENT C1Q B CHAIN
C1QB
120570
1242
ENSG00000173369
OTTHUMG00000002896
P02746
BE0002095

Gene Info:

Gene Biotype	PROTEIN_CODING

(0 More Sources)

Gene Categories: Category Details

CELL SURFACE
DRUGGABLE GENOME

Publications:

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov
Wang Y et al., 2004, Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro., Angiogenesis
Deveuve Q et al., 2020, The Proteolytic Cleavage of Therapeutic Monoclonal Antibody Hinge Region: More Than a Matter of Subclass., Front Immunol
Hiatt A et al., 2014, Glycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacy., Proc Natl Acad Sci U S A
Wang F et al., 2013, Immobilized metal affinity chromatography and human serum proteomics., J Chromatogr B Analyt Technol Biomed Life Sci
Boyle MD, 1981, Inhibition by zinc of the binding of C1 to antigen-antibody complexes., Biochem Biophys Res Commun

PALIVIZUMAB C1QB

Interaction Score: 4.73

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423 24711420

Sources:
DrugBank
DACLIZUMAB C1QB

Interaction Score: 2.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423

Sources:
DrugBank
BEVACIZUMAB C1QB

Interaction Score: 0.92

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
17139284 17016423 15886877

Sources:
DrugBank
CETUXIMAB C1QB

Interaction Score: 0.77

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
32117299 17139284 17016423

Sources:
DrugBank
ZINC CHLORIDE C1QB

Interaction Score: 0.2

Interaction Types & Directionality:

modulator

Interaction Info:

PMIDs:
7332580

Sources:
DrugBank
METHYLDOPA C1QB

Interaction Score: 0.12

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
23896426

Sources:
DrugBank

Ensembl: ENSG00000173369
- Version: 101_38
Alternate Names:

C1QB Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0002095

Version: 5.1.7

Alternate Names:

C1QB DrugBank Gene Name

P02746 UniProt Accession

713 Entrez Gene Id

Gene Info:

Publications:

Deveuve Q et al., 2020, The Proteolytic Cleavage of Therapeutic Monoclonal Antibody Hinge Region: More Than a Matter of Subclass., Front Immunol

Hiatt A et al., 2014, Glycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacy., Proc Natl Acad Sci U S A

Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov

HingoraniCasas: ENSG00000173369
- Version: 31-May-2017
Alternate Names:

ENSG00000173369 Gene Symbol

C1QB Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: C1QB
- Version: 05-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CELL SURFACE

Publications:

C1QB	DrugBank Gene Name
P02746	UniProt Accession
713	Entrez Gene Id

C1QB Gene Record

C1QB 713 Druggable Genome

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

PALIVIZUMAB C1QB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423 24711420

Sources: DrugBank

DACLIZUMAB C1QB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423

Sources: DrugBank

BEVACIZUMAB C1QB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 17139284 17016423 15886877

Sources: DrugBank

CETUXIMAB C1QB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 32117299 17139284 17016423

Sources: DrugBank

ZINC CHLORIDE C1QB

Interaction Types & Directionality: modulator

Interaction Info:

PMIDs: 7332580

Sources: DrugBank

METHYLDOPA C1QB

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 23896426

Sources: DrugBank

Ensembl: ENSG00000173369

Alternate Names: C1QB Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

DrugBank: BE0002095

Alternate Names: C1QB DrugBank Gene Name P02746 UniProt Accession 713 Entrez Gene Id

Gene Info:

HingoraniCasas: ENSG00000173369

Alternate Names: ENSG00000173369 Gene Symbol C1QB Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

GO: C1QB

Alternate Names:

Gene Info:

Gene Categories: CELL SURFACE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423 24711420

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
17139284 17016423 15886877

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
32117299 17139284 17016423

Sources:
DrugBank

Interaction Types & Directionality:

modulator

PMIDs:
7332580

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
23896426

Sources:
DrugBank

Alternate Names:

C1QB Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

C1QB DrugBank Gene Name

P02746 UniProt Accession

713 Entrez Gene Id

Alternate Names:

ENSG00000173369 Gene Symbol

C1QB Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Gene Categories:

CELL SURFACE