BRSK1 Gene Record

  • BRSK1 84446 Druggable GenomeClinically Actionable

    Alternate Names:

    84446
    BR SERINE/THREONINE KINASE 1
    BRSK1
    hSAD1
    609235
    18994
    ENSG00000160469
    OTTHUMG00000180735
    BR SERINE/THREONINE-PROTEIN KINASE 1 (EC 2.7.1.37) (SAD1 KINASE) (SAD1A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8TDC3]
    1946
    Q8TDC3
    BRSK1_HUMAN
    SERINE/THREONINE-PROTEIN KINASE BRSK1
    NP_115806
    NM_032430
    SADB
    KIAA1811
    SAD1

    Gene Info:

    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Uniprot Status Swiss-Prot
    Interpro Name Serine/threonine- / dual-specificity protein kinase, catalytic domain
    Interpro Short Name Ser/Thr_dual-sp_kinase_dom
    Interpro Acc IPR002290
    Interpro Type Domain
    Human Readable Name KINASE
    GuideToPharmacology Gene Category Name BRSK subfamily
    GuideToPharmacology Gene Category ID 475
    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    KINASE
    SERINE THREONINE KINASE
    DRUGGABLE GENOME
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

  • CHEMBL2203843   BRSK1

    Interaction Score: 1.06

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Details of the Assay for Interaction Measured as % inhibition using 1μM compound.
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False

    PMIDs:
    None found


    Sources:
    GuideToPharmacology

  • GW843682X   BRSK1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SNS-314   BRSK1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALISERTIB   BRSK1

    Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • OSI-632   BRSK1

    Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ALSTERPAULLONE   BRSK1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SOTRASTAURIN   BRSK1

    Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GW441756X   BRSK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CHEMBL225519   BRSK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • GEFITINIB   BRSK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TOZASERTIB   BRSK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • LINIFANIB   BRSK1

    Interaction Score: 0.05

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • RG-1530   BRSK1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • SP-600125   BRSK1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • DOVITINIB   BRSK1

    Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CYC-116   BRSK1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • TAE-684   BRSK1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • PF-00562271   BRSK1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • ILORASERTIB   BRSK1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • CENISERTIB   BRSK1

    Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Ensembl: ENSG00000160469

    • Version: 101_38

    Alternate Names:
    BRSK1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • HopkinsGroom: Q8TDC3

    • Version: 11-September-2012

    Alternate Names:
    BRSK1 Uniprot Gene Name
    ENSG00000160469 Ensembl Gene Id
    SERINE/THREONINE-PROTEIN KINASE BRSK1 Uniprot Protein Name

    Gene Info:
    Uniprot Evidence 1: Evidence at protein level
    Human Readable Name DRUGGABLE GENOME
    Uniprot Status Swiss-Prot

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

  • RussLampel: ENSG00000160469

    • Version: 26-July-2011

    Alternate Names:
    BR SERINE/THREONINE-PROTEIN KINASE 1 (EC 2.7.1.37) (SAD1 KINASE) (SAD1A). [SOURCE:UNIPROT/SWISSPROT;ACC:Q8TDC3] Description
    ENSG00000160469 Ensembl Gene Id
    BRSK1 Display Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • GuideToPharmacology: 84446

    • Version: 29-September-2020

    Alternate Names:
    18994 HUGO Gene ID
    18994 HUGO Gene Symbol
    BR serine/threonine kinase 1 HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name BRSK subfamily
    GuideToPharmacology Gene Category ID 475

    Gene Categories:
    ENZYME

    Publications:

  • HingoraniCasas: ENSG00000160469

    • Version: 31-May-2017

    Alternate Names:
    ENSG00000160469 Gene Symbol
    BRSK1 Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

  • IDG: BRSK1

    • Version: 15-July-2019

    Alternate Names:
    BRSK1 Gene Symbol

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • dGene: BRSK1

    • Version: 27-Jun-2013

    Alternate Names:
    84446 Gene ID
    hSAD1 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, SERINE THREONINE KINASE

    Publications:

  • GO: BRSK1

    • Version: 01-May-2021

    Alternate Names:
    KIAA1811 GO Gene Synonym
    SAD1 GO Gene Synonym
    SADB GO Gene Synonym

    Gene Info:

    Gene Categories:
    SERINE THREONINE KINASE

    Publications:

  • Pharos: BRSK1

    • Version: 01-May-2021

    Alternate Names:
    Serine/threonine-protein kinase BRSK1 Gene Name
    Q8TDC3 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE

    Publications:

  • DTC: BRSK1

    • Version: 02-September-2020

    Alternate Names:

    Gene Info:

    Publications:

  • FoundationOneGenes: BRSK1

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications: