• BLK 640 Druggable Genome

    Alternate Names:

    640
    BLK PROTO-ONCOGENE, SRC FAMILY TYROSINE KINASE
    BLK
    MODY11
    191305
    1057
    ENSG00000136573
    OTTHUMG00000090729
    1940
    NP_001706
    P51451
    NM_001715
    TYROSINE-PROTEIN KINASE BLK
    BLK_HUMAN
    p55-Blk
    B lymphocyte kinase
    TYROSINE-PROTEIN KINASE BLK (EC 2.7.1.112) (B LYMPHOCYTE KINASE) (P55- BLK). [SOURCE:UNIPROT/SWISSPROT;ACC:P51451]
    T74307
    MGC10442

    Gene Info:

    GuideToPharmacology Gene Category Name Src family
    GuideToPharmacology Gene Category ID 619
    Target Class Enzymes
    Target Subclass EC:2.7.10.2
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name DRUGGABLE GENOME
    Human Readable Name KINASE
    Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain
    Uniprot Evidence 1: Evidence at protein level
    Interpro Type Domain
    Interpro Acc IPR001245
    Gene Biotype PROTEIN_CODING
    (11 More Sources)

    Gene Categories: Category Details

    KINASE
    TYROSINE KINASE
    DRUGGABLE GENOME
    ENZYME
    TRANSCRIPTION FACTOR
  • Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.13

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.11

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.1

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction? False
    Endogenous Drug? False
    Specific Action of the Ligand Inhibition

    PMIDs:
    None found


  • Interaction Score: 0.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Notes

    PMIDs:
    None found


    Sources:
    TALC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.08

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Inhibition
    Endogenous Drug? False
    Direct Interaction? False

    PMIDs:
    None found


  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    Novel drug target Novel Target
    Trial Name ENMD-2076

    PMIDs:
    None found


    Sources:
    TdgClinicalTrial

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Mechanism of Interaction SRC inhibitor
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 0.06

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:

    PMIDs:
    19035792


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction SRC inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.03

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    inhibitor (inhibitory)

    Interaction Info:
    Direct Interaction yes
    Mechanism of Interaction SRC inhibitor

    PMIDs:
    None found


  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

  • Interaction Score: 0.02

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    None found


    Sources:
    DTC

    • Version: 101_38

    Alternate Names:
    BLK Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

    • Version: January-2014

    Alternate Names:
    BLK Gene Symbol

    Gene Info:
    Target Class Enzymes
    Target Subclass EC:2.7.10.2

    Publications:

    • Version: 11-September-2012

    Alternate Names:
    640 Entrez Gene Id
    ENSG00000136573 Ensembl Gene Id
    BLK Uniprot Gene Name

    Gene Info:
    Uniprot Status Swiss-Prot
    Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    KINASE, DRUGGABLE GENOME

    Publications:

    • Version: 26-July-2011

    Alternate Names:
    BLK Display Id
    TYROSINE-PROTEIN KINASE BLK (EC 2.7.1.112) (B LYMPHOCYTE KINASE) (P55- BLK). [SOURCE:UNIPROT/SWISSPROT;ACC:P51451] Description
    ENSG00000136573 Ensembl Gene Id

    Gene Info:
    Human Readable Name DRUGGABLE GENOME

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 29-September-2020

    Alternate Names:
    1057 HUGO Gene ID
    1057 HUGO Gene Symbol
    BLK proto-oncogene, Src family tyrosine kinase HUGO Gene Name

    Gene Info:
    GuideToPharmacology Gene Category Name Src family
    GuideToPharmacology Gene Category ID 619

    Gene Categories:
    ENZYME

    Publications:

  • NCI: BLK

    • Version: 14-September-2017
  • DTC: BLK

    • Version: 02-September-2020
    • Version: 31-May-2017

    Alternate Names:
    ENSG00000136573 Gene Symbol
    BLK Ensembl Id

    Gene Info:

    Gene Categories:
    DRUGGABLE GENOME

    Publications:

    • Version: 12-May-2016

    Alternate Names:
    BLK Gene Symbol

    Gene Info:

    Publications:

    • Version: chembl_23

    Alternate Names:
    BLK GENE_SYMBOL
    Tyrosine-protein kinase Blk UNIPROT
    B lymphocyte kinase UNIPROT

    Gene Info:

    Publications:

    • Version: 19.3

    Alternate Names:
    ENSG00000136573 Ensembl Gene ID
    MGC10442 Human Protein Atlas Gene Synonym
    BLK proto-oncogene, Src family tyrosine kinase Human Protein Atlas Gene Description

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

    • Version: 27-Jun-2013

    Alternate Names:
    640 Gene ID
    MODY11 dGene Synonym

    Gene Info:

    Gene Categories:
    KINASE, TYROSINE KINASE

    Publications:

    • Version: 2020.06.01

    Alternate Names:
    BLK TTD Gene Abbreviation
    T74307 TTD Target ID

    Gene Info:

    Publications:

    • Version: 01-May-2021

    Alternate Names:
    Tyrosine-protein kinase Blk Gene Name
    P51451 UniProt ID

    Gene Info:

    Gene Categories:
    KINASE, TRANSCRIPTION FACTOR

    Publications:

  • GO: BLK

    • Version: 01-May-2021

    Alternate Names:

    Gene Info:

    Gene Categories:
    TYROSINE KINASE

    Publications: