• BDKRB1 623 Druggable Genome

    Alternate Names:

    623
    BRADYKININ RECEPTOR B1
    BDKRB1
    B1BKR
    B1R
    BDKRB2
    BKB1R
    BKR1
    BRADYB1
    600337
    1029
    ENSG00000100739
    OTTHUMG00000171412
    P46663
    BKRB1_HUMAN
    B1 BRADYKININ RECEPTOR
    BK-1 receptor
    41
    B<sub>1</sub> receptor
    NP_000701
    NM_000710
    B1 BRADYKININ RECEPTOR (BK-1 RECEPTOR) (B1R). [SOURCE:UNIPROT/SWISSPROT;ACC:P46663]
    PA79
    T58589

    Gene Info:

    Interpro Short Name 7TM_GPCR_Rhodpsn
    Interpro Type Family
    Human Readable Name G PROTEIN COUPLED RECEPTOR
    Uniprot Status Swiss-Prot
    Interpro Acc IPR000276
    Human Readable Name DRUGGABLE GENOME
    Uniprot Evidence 1: Evidence at protein level
    Interpro Name GPCR, rhodopsin-like, 7TM
    GuideToPharmacology Gene Category Name Bradykinin receptors
    GuideToPharmacology Gene Category ID 10
    Gene Biotype PROTEIN_CODING
    (6 More Sources)

    Gene Categories: Category Details

    G PROTEIN COUPLED RECEPTOR
    DRUGGABLE GENOME
  • Interaction Score: 21.26

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Bradykinin B1 receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Bradykinin B1 receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 10.63

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Mechanism of Interaction Bradykinin B1 receptor antagonist
    Direct Interaction yes

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    20712529


    Sources:
    PharmGKB

  • Interaction Score: 5.32

    Interaction Types & Directionality:
    agonist (activating)

    Interaction Info:
    Endogenous Drug? True
    Specific Action of the Ligand Full agonist

    PMIDs:
    None found


  • Interaction Score: 5.32

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:
    Specific Action of the Ligand Antagonist
    Endogenous Drug? False

    PMIDs:
    None found