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BARD1 Gene Record

  • Summary
  • Interactions
  • Claims
  • BARD1 580 Clinically Actionable

    Alternate Names:

    580
    BRCA1 ASSOCIATED RING DOMAIN 1
    BARD1
    601593
    952
    ENSG00000138376
    OTTHUMG00000133016
    PA25256
    549

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (4 More Sources)

    Gene Categories: Category Details

    TUMOR SUPPRESSOR
    CLINICALLY ACTIONABLE

    Publications:

    Coté D et al., 2018, Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH)., PLoS One
    Parrotta R et al., 2017, A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair., J Thorac Oncol
    Ozden O et al., 2016, Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer., Sci Rep
  • OLAPARIB   BARD1

    Interaction Score: 1.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27197561 28389374


    Sources:
    CIViC

  • APITOLISIB   BARD1

    Interaction Score: 1.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28389374


    Sources:
    CIViC

  • TRASTUZUMAB   BARD1

    Interaction Score: 1.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30071039


    Sources:
    PharmGKB

  • DOCETAXEL   BARD1

    Interaction Score: 0.32

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30071039


    Sources:
    PharmGKB

  • CARBOPLATIN   BARD1

    Interaction Score: 0.31

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    30071039


    Sources:
    PharmGKB

  • Ensembl: ENSG00000138376

    • Version: 101_38

    Alternate Names:
    BARD1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • PharmGKB: BARD1

    • Version: 18-August-2020

    Alternate Names:
    PA25256 PharmGKB ID

    Gene Info:

    Publications:
    Coté D et al., 2018, Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH)., PLoS One

  • CIViC: BARD1

    • Version: 14-September-2020

    Alternate Names:
    580 Entrez Gene ID
    549 CIViC Gene ID

    Gene Info:

    Publications:
    Parrotta R et al., 2017, A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair., J Thorac Oncol
    Ozden O et al., 2016, Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer., Sci Rep

  • Tempus: BARD1

    • Version: 11-November-2018

    Alternate Names:
    BARD1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • MskImpact: BARD1

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • GO: BARD1

    • Version: 01-February-2022

    Alternate Names:

    Gene Info:

    Gene Categories:
    TUMOR SUPPRESSOR

    Publications:

  • FoundationOneGenes: BARD1

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: BARD1

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21