DGIdb - BAP1 Gene Record

BAP1 8314 Clinically ActionableDrug Resistance

Alternate Names:

8314
BRCA1 ASSOCIATED PROTEIN 1
BAP1
HUCEP-13
UCHL2
hucep-6
603089
950
ENSG00000163930
OTTHUMG00000158392
70
2332
NM_004656
Q92560
NP_004647
KIAA0272
Ubiquitin carboxyl-terminal hydrolase BAP1
TPDS

Gene Info:

GuideToPharmacology Gene Category Name	C12: Ubiquitin C-terminal hydrolase
GuideToPharmacology Gene Category ID	729
Gene Biotype	PROTEIN_CODING

(8 More Sources)

Gene Categories: Category Details

TUMOR SUPPRESSOR
DRUG RESISTANCE
PROTEASE
CLINICALLY ACTIONABLE
ENZYME

Publications:

Landreville et al., 2012, Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma., Clin. Cancer Res.
Hsieh et al., 2017, Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma., Eur. Urol.
Parrotta R et al., 2017, A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair., J Thorac Oncol
Peña-Llopis S et al., 2012, BAP1 loss defines a new class of renal cell carcinoma., Nat Genet

PANOBINOSTAT BAP1

Interaction Score: 1.11

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22038994

Sources:
CIViC
OLAPARIB BAP1

Interaction Score: 0.95

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28389374 22683710

Sources:
CIViC
APITOLISIB BAP1

Interaction Score: 0.79

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
28389374

Sources:
CIViC
EVEROLIMUS BAP1

Interaction Score: 0.46

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
27751729

Sources:
CIViC
SUNITINIB BAP1

Interaction Score: 0.44

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
27751729

Sources:
CIViC
VORINOSTAT BAP1

Interaction Score: 0.4

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
22038994

Sources:
CIViC

Ensembl: ENSG00000163930
- Version: 101_38
Alternate Names:

BAP1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
GuideToPharmacology: 8314
- Version: 29-September-2020
Alternate Names:

950 HUGO Gene ID

950 HUGO Gene Symbol

BRCA1 associated protein 1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name C12: Ubiquitin C-terminal hydrolase

GuideToPharmacology Gene Category ID 729

Gene Categories:

ENZYME

Publications:

CIViC: BAP1

Version: 14-September-2020

Alternate Names:

8314 Entrez Gene ID

70 CIViC Gene ID

Gene Info:

Gene Categories:

DRUG RESISTANCE

Publications:

Landreville et al., 2012, Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma., Clin. Cancer Res.

Hsieh et al., 2017, Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma., Eur. Urol.

Parrotta R et al., 2017, A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair., J Thorac Oncol

HumanProteinAtlas: BAP1
- Version: 19.3
Alternate Names:

ENSG00000163930 Ensembl Gene ID

hucep-6 Human Protein Atlas Gene Synonym

KIAA0272 Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories:

ENZYME

Publications:
Pharos: BAP1
- Version: 03-September-2020
Alternate Names:

Ubiquitin carboxyl-terminal hydrolase BAP1 Gene Name

Q92560 UniProt ID

Gene Info:

Gene Categories:

ENZYME

Publications:
GO: BAP1
- Version: 05-September-2020
Alternate Names:

KIAA0272 GO Gene Synonym

hucep-6 GO Gene Synonym

Gene Info:

Gene Categories:

TUMOR SUPPRESSOR, PROTEASE

Publications:
Tempus: BAP1
- Version: 11-November-2018
Alternate Names:

BAP1 Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
dGene: BAP1
- Version: 27-Jun-2013
Alternate Names:

8314 Gene ID

HUCEP-13 dGene Synonym

TPDS dGene Synonym

Gene Info:

Gene Categories:

PROTEASE

Publications:
MskImpact: BAP1
- Version: May-2015
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
FoundationOneGenes: BAP1
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
CarisMolecularIntelligence: BAP1
- Version: 04-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
Oncomine: BAP1
- Version: v3
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:

950	HUGO Gene ID
950	HUGO Gene Symbol
BRCA1 associated protein 1	HUGO Gene Name

ENSG00000163930	Ensembl Gene ID
hucep-6	Human Protein Atlas Gene Synonym
KIAA0272	Human Protein Atlas Gene Synonym

Ubiquitin carboxyl-terminal hydrolase BAP1	Gene Name
Q92560	UniProt ID

BAP1 Gene Record

BAP1 8314 Clinically ActionableDrug Resistance

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

PANOBINOSTAT BAP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22038994

Sources: CIViC

OLAPARIB BAP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 28389374 22683710

Sources: CIViC

APITOLISIB BAP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 28389374

Sources: CIViC

EVEROLIMUS BAP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 27751729

Sources: CIViC

SUNITINIB BAP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 27751729

Sources: CIViC

VORINOSTAT BAP1

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 22038994

Sources: CIViC

Ensembl: ENSG00000163930

Alternate Names: BAP1 Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

GuideToPharmacology: 8314

Alternate Names: 950 HUGO Gene ID 950 HUGO Gene Symbol BRCA1 associated protein 1 HUGO Gene Name

Gene Info: GuideToPharmacology Gene Category Name C12: Ubiquitin C-terminal hydrolase GuideToPharmacology Gene Category ID 729

Gene Categories: ENZYME

Publications:

CIViC: BAP1

Alternate Names: 8314 Entrez Gene ID 70 CIViC Gene ID

Gene Info:

Gene Categories: DRUG RESISTANCE

HumanProteinAtlas: BAP1

Alternate Names: ENSG00000163930 Ensembl Gene ID hucep-6 Human Protein Atlas Gene Synonym KIAA0272 Human Protein Atlas Gene Synonym

Gene Info:

Gene Categories: ENZYME

Publications:

Pharos: BAP1

Alternate Names: Ubiquitin carboxyl-terminal hydrolase BAP1 Gene Name Q92560 UniProt ID

Gene Info:

Gene Categories: ENZYME

Publications:

GO: BAP1

Alternate Names: KIAA0272 GO Gene Synonym hucep-6 GO Gene Synonym

Gene Info:

Gene Categories: TUMOR SUPPRESSOR, PROTEASE

Publications:

Tempus: BAP1

Alternate Names: BAP1 Gene Symbol

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

dGene: BAP1

Alternate Names: 8314 Gene ID HUCEP-13 dGene Synonym TPDS dGene Synonym

Gene Info:

Gene Categories: PROTEASE

Publications:

MskImpact: BAP1

Alternate Names:

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

FoundationOneGenes: BAP1

Interaction Types & Directionality:

n/a

PMIDs:
22038994

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
28389374 22683710

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
28389374

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
27751729

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
27751729

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
22038994

Sources:
CIViC

Alternate Names:

BAP1 Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

950 HUGO Gene ID

950 HUGO Gene Symbol

BRCA1 associated protein 1 HUGO Gene Name

Gene Info:

GuideToPharmacology Gene Category Name C12: Ubiquitin C-terminal hydrolase

GuideToPharmacology Gene Category ID 729

Gene Categories:

ENZYME

Alternate Names:

8314 Entrez Gene ID

70 CIViC Gene ID

Gene Categories:

DRUG RESISTANCE

Alternate Names:

ENSG00000163930 Ensembl Gene ID

hucep-6 Human Protein Atlas Gene Synonym

KIAA0272 Human Protein Atlas Gene Synonym

Gene Categories:

ENZYME

Alternate Names:

Ubiquitin carboxyl-terminal hydrolase BAP1 Gene Name

Q92560 UniProt ID

Gene Categories:

ENZYME

Alternate Names:

KIAA0272 GO Gene Synonym

hucep-6 GO Gene Synonym

Gene Categories:

TUMOR SUPPRESSOR, PROTEASE

Alternate Names:

BAP1 Gene Symbol

Gene Categories:

CLINICALLY ACTIONABLE

Alternate Names:

8314 Gene ID

HUCEP-13 dGene Synonym

TPDS dGene Synonym

Gene Categories:

PROTEASE

Gene Categories:

CLINICALLY ACTIONABLE

Gene Categories:

CLINICALLY ACTIONABLE

Gene Categories:

CLINICALLY ACTIONABLE

Gene Categories:

CLINICALLY ACTIONABLE