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BAP1 Gene Record

  • Summary
  • Interactions
  • Claims
  • BAP1 8314 Clinically ActionableDrug Resistance

    Alternate Names:

    8314
    BRCA1 ASSOCIATED PROTEIN 1
    BAP1
    HUCEP-13
    UCHL2
    hucep-6
    603089
    950
    ENSG00000163930
    OTTHUMG00000158392
    70
    Q92560
    KIAA0272
    TPDS
    Ubiquitin carboxyl-terminal hydrolase BAP1

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (7 More Sources)

    Gene Categories: Category Details

    TUMOR SUPPRESSOR
    DRUG RESISTANCE
    PROTEASE
    CLINICALLY ACTIONABLE
    ENZYME

    Publications:

    Landreville et al., 2012, Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma., Clin. Cancer Res.
    Hsieh et al., 2017, Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma., Eur. Urol.
    Parrotta R et al., 2017, A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair., J Thorac Oncol
    Peña-Llopis S et al., 2012, BAP1 loss defines a new class of renal cell carcinoma., Nat Genet
  • PANOBINOSTAT   BAP1

    Interaction Score: 1.21

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22038994


    Sources:
    CIViC

  • OLAPARIB   BAP1

    Interaction Score: 1.14

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28389374 22683710


    Sources:
    CIViC

  • APITOLISIB   BAP1

    Interaction Score: 0.98

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    28389374


    Sources:
    CIViC

  • SUNITINIB   BAP1

    Interaction Score: 0.53

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27751729


    Sources:
    CIViC

  • EVEROLIMUS   BAP1

    Interaction Score: 0.53

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    27751729


    Sources:
    CIViC

  • VORINOSTAT   BAP1

    Interaction Score: 0.45

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    22038994


    Sources:
    CIViC

  • Ensembl: ENSG00000163930

    • Version: 101_38

    Alternate Names:
    BAP1 Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • CIViC: BAP1

    • Version: 14-September-2020

    Alternate Names:
    8314 Entrez Gene ID
    70 CIViC Gene ID

    Gene Info:

    Gene Categories:
    DRUG RESISTANCE

    Publications:
    Landreville et al., 2012, Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma., Clin. Cancer Res.
    Hsieh et al., 2017, Genomic Biomarkers of a Randomized Trial Comparing First-line Everolimus and Sunitinib in Patients with Metastatic Renal Cell Carcinoma., Eur. Urol.
    Parrotta R et al., 2017, A Novel BRCA1-Associated Protein-1 Isoform Affects Response of Mesothelioma Cells to Drugs Impairing BRCA1-Mediated DNA Repair., J Thorac Oncol

  • HumanProteinAtlas: BAP1

    • Version: 19.3

    Alternate Names:
    ENSG00000163930 Ensembl Gene ID
    hucep-6 Human Protein Atlas Gene Synonym
    KIAA0272 Human Protein Atlas Gene Synonym

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • GO: BAP1

    • Version: 01-February-2022

    Alternate Names:
    KIAA0272 GO Gene Synonym
    hucep-6 GO Gene Synonym

    Gene Info:

    Gene Categories:
    TUMOR SUPPRESSOR, PROTEASE

    Publications:

  • Tempus: BAP1

    • Version: 11-November-2018

    Alternate Names:
    BAP1 Gene Symbol

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • dGene: BAP1

    • Version: 27-Jun-2013

    Alternate Names:
    8314 Gene ID
    HUCEP-13 dGene Synonym
    TPDS dGene Synonym

    Gene Info:

    Gene Categories:
    PROTEASE

    Publications:

  • Pharos: BAP1

    • Version: 01-February-2022

    Alternate Names:
    Ubiquitin carboxyl-terminal hydrolase BAP1 Gene Name
    Q92560 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

  • MskImpact: BAP1

    • Version: May-2015

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • FoundationOneGenes: BAP1

    • Version: 03-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • CarisMolecularIntelligence: BAP1

    • Version: 04-September-2020

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

  • Oncomine: BAP1

    • Version: v3

    Alternate Names:

    Gene Info:

    Gene Categories:
    CLINICALLY ACTIONABLE

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

The dgidb.org website does not provide any medical or healthcare products, services or advice, and is not for medical emergencies or urgent situations. IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY, CALL YOUR DOCTOR OR 911 IMMEDIATELY. Information contained on this website is not a substitute for a doctor's medical judgment or advice. We recommend that you discuss your specific, individual health concerns with your doctor or health care professional.

DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21