DGIdb - B2M Gene Record

B2M 567 Druggable GenomeClinically ActionableDrug Resistance

Alternate Names:

567
BETA-2-MICROGLOBULIN
B2M
IMD43
109700
914
ENSG00000166710
OTTHUMG00000131247
CDABP0092
HDCMA22P
P61769
537
BE0003777

Gene Info:

Gene Biotype	PROTEIN_CODING

(5 More Sources)

Gene Categories: Category Details

DRUG RESISTANCE
EXTERNAL SIDE OF PLASMA MEMBRANE
DRUGGABLE GENOME
CLINICALLY ACTIONABLE

Publications:

Ibrahim et al., 1994, Urinary phospholipids excretion in neonates treated with amikacin., Int J Clin Pharmacol Res
Zaretsky et al., 2016, Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma., N. Engl. J. Med.
Lomo et al., 1998, Flexibility of the thyroiditogenic T cell repertoire for murine autoimmune thyroiditis in CD8-deficient (beta2m -/-) and T cell receptor Vbeta(c) congenic mice., Autoimmunity
Deng NJ et al., 2006, Molecular basis for the Cu2+ binding-induced destabilization of beta2-microglobulin revealed by molecular dynamics simulation., Biophys J
Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

THYROGLOBULIN B2M

Interaction Score: 7.57

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
9609129

Sources:
NCI
INDOLE-3-BUTYRIC ACID B2M

Interaction Score: 4.54

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
10592235

Sources:
DrugBank
AMIKACIN B2M

Interaction Score: 4.54

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
7672871

Sources:
NCI
PEMBROLIZUMAB B2M

Interaction Score: 1.03

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
27433843

Sources:
CIViC
COPPER B2M

Interaction Score: 0.16

Interaction Types & Directionality:

n/a

Interaction Info:

PMIDs:
16513784

Sources:
DrugBank

Ensembl: ENSG00000166710
- Version: 101_38
Alternate Names:

B2M Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Publications:
CIViC: B2M
- Version: 14-September-2020
Alternate Names:

567 Entrez Gene ID

537 CIViC Gene ID

Gene Info:

Gene Categories:

DRUG RESISTANCE

Publications:

Zaretsky et al., 2016, Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma., N. Engl. J. Med.

DrugBank: BE0003777

Version: 5.1.7

Alternate Names:

B2M DrugBank Gene Name

P61769 UniProt Accession

567 Entrez Gene Id

Gene Info:

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Deng NJ et al., 2006, Molecular basis for the Cu2+ binding-induced destabilization of beta2-microglobulin revealed by molecular dynamics simulation., Biophys J

NCI: B2M

Version: 14-September-2017

Alternate Names:

Gene Info:

Publications:

Ibrahim et al., 1994, Urinary phospholipids excretion in neonates treated with amikacin., Int J Clin Pharmacol Res

Lomo et al., 1998, Flexibility of the thyroiditogenic T cell repertoire for murine autoimmune thyroiditis in CD8-deficient (beta2m -/-) and T cell receptor Vbeta(c) congenic mice., Autoimmunity

HingoraniCasas: ENSG00000166710
- Version: 31-May-2017
Alternate Names:

ENSG00000166710 Gene Symbol

B2M Ensembl Id

Gene Info:

Gene Categories:

DRUGGABLE GENOME

Publications:
GO: B2M
- Version: 05-September-2020
Alternate Names:

CDABP0092 GO Gene Synonym

HDCMA22P GO Gene Synonym

Gene Info:

Gene Categories:

DRUG RESISTANCE, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:
Tempus: B2M
- Version: 11-November-2018
Alternate Names:

B2M Gene Symbol

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
MskImpact: B2M
- Version: May-2015
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:
FoundationOneGenes: B2M
- Version: 03-September-2020
Alternate Names:

Gene Info:

Gene Categories:

CLINICALLY ACTIONABLE

Publications:

B2M	DrugBank Gene Name
P61769	UniProt Accession
567	Entrez Gene Id

B2M Gene Record

B2M 567 Druggable GenomeClinically ActionableDrug Resistance

Alternate Names:

Gene Info:

Gene Categories: Category Details

Publications:

THYROGLOBULIN B2M

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 9609129

Sources: NCI

INDOLE-3-BUTYRIC ACID B2M

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 10592235

Sources: DrugBank

AMIKACIN B2M

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 7672871

Sources: NCI

PEMBROLIZUMAB B2M

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 27433843

Sources: CIViC

COPPER B2M

Interaction Types & Directionality: n/a

Interaction Info:

PMIDs: 16513784

Sources: DrugBank

Ensembl: ENSG00000166710

Alternate Names: B2M Ensembl Gene Name

Gene Info: Gene Biotype PROTEIN_CODING

Publications:

CIViC: B2M

Alternate Names: 567 Entrez Gene ID 537 CIViC Gene ID

Gene Info:

Gene Categories: DRUG RESISTANCE

Publications: Zaretsky et al., 2016, Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma., N. Engl. J. Med.

DrugBank: BE0003777

Alternate Names: B2M DrugBank Gene Name P61769 UniProt Accession 567 Entrez Gene Id

Gene Info:

Publications: Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res. Deng NJ et al., 2006, Molecular basis for the Cu2+ binding-induced destabilization of beta2-microglobulin revealed by molecular dynamics simulation., Biophys J

NCI: B2M

Alternate Names:

Gene Info:

HingoraniCasas: ENSG00000166710

Alternate Names: ENSG00000166710 Gene Symbol B2M Ensembl Id

Gene Info:

Gene Categories: DRUGGABLE GENOME

Publications:

GO: B2M

Alternate Names: CDABP0092 GO Gene Synonym HDCMA22P GO Gene Synonym

Gene Info:

Gene Categories: DRUG RESISTANCE, EXTERNAL SIDE OF PLASMA MEMBRANE

Publications:

Tempus: B2M

Alternate Names: B2M Gene Symbol

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

MskImpact: B2M

Alternate Names:

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

FoundationOneGenes: B2M

Alternate Names:

Gene Info:

Gene Categories: CLINICALLY ACTIONABLE

Publications:

Interaction Types & Directionality:

n/a

PMIDs:
9609129

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
10592235

Sources:
DrugBank

Interaction Types & Directionality:

n/a

PMIDs:
7672871

Sources:
NCI

Interaction Types & Directionality:

n/a

PMIDs:
27433843

Sources:
CIViC

Interaction Types & Directionality:

n/a

PMIDs:
16513784

Sources:
DrugBank

Alternate Names:

B2M Ensembl Gene Name

Gene Info:

Gene Biotype PROTEIN_CODING

Alternate Names:

567 Entrez Gene ID

537 CIViC Gene ID

Gene Categories:

DRUG RESISTANCE

Publications:

Zaretsky et al., 2016, Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma., N. Engl. J. Med.

Alternate Names:

B2M DrugBank Gene Name

P61769 UniProt Accession

567 Entrez Gene Id

Publications:

Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.

Deng NJ et al., 2006, Molecular basis for the Cu2+ binding-induced destabilization of beta2-microglobulin revealed by molecular dynamics simulation., Biophys J

Alternate Names:

ENSG00000166710 Gene Symbol

B2M Ensembl Id

Gene Categories:

DRUGGABLE GENOME

Alternate Names:

CDABP0092 GO Gene Synonym

HDCMA22P GO Gene Synonym

Gene Categories:

DRUG RESISTANCE, EXTERNAL SIDE OF PLASMA MEMBRANE

Alternate Names:

B2M Gene Symbol

Gene Categories:

CLINICALLY ACTIONABLE

Gene Categories:

CLINICALLY ACTIONABLE

Gene Categories:

CLINICALLY ACTIONABLE