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AXL 558 Druggable GenomeClinically Actionable
Alternate Names:
558 AXL RECEPTOR TYROSINE KINASE AXL ARK JTK11 Tyro7 UFO 109135 905 ENSG00000167601 OTTHUMG00000182727 AXL oncogene Tyrosine-protein kinase receptor UFO P30530 UFO_HUMAN TYROSINE-PROTEIN KINASE RECEPTOR UFO PRECURSOR (EC 2.7.1.112) (AXL ONCOGENE). [SOURCE:UNIPROT/SWISSPROT;ACC:P30530] 1835 NP_001690 NM_001699 Tyrosine-protein kinase UFO T82383 BE0009412 Gene Info:
Uniprot Status Swiss-Prot Human Readable Name DRUGGABLE GENOME Interpro Acc IPR001245 Human Readable Name KINASE Interpro Type Domain Uniprot Evidence 1: Evidence at protein level Interpro Name Serine-threonine/tyrosine-protein kinase catalytic domain Interpro Short Name Ser-Thr/Tyr_kinase_cat_dom GuideToPharmacology Gene Category Name Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family GuideToPharmacology Gene Category ID 328 Target Class Receptors Target Subclass EC:2.7.10.1 Gene Biotype PROTEIN_CODING Gene Categories: Category Details
CELL SURFACE KINASE TYROSINE KINASE DRUGGABLE GENOME CLINICALLY ACTIONABLE ENZYME Publications:
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Interaction Score: 3.92
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Score: 1.96
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Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction yes Mechanism of Interaction Tyrosine-protein kinase receptor UFO inhibitor -
Interaction Score: 1.52
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Direct Interaction? False Endogenous Drug? False Specific Action of the Ligand Inhibition -
Interaction Score: 1.31
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Endogenous Drug? False Specific Action of the Ligand Inhibition Direct Interaction? False -
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Mechanism of Interaction Tyrosine-protein kinase receptor UFO inhibitor Direct Interaction yes -
Interaction Score: 0.33
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Specific Action of the Ligand Inhibition Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.3
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Interaction Score: 0.24
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Details of the Assay for Interaction Inhibition of <i>in vitro</i> biochemical activity by EMD Millipore assay. Specific Action of the Ligand Inhibition Endogenous Drug? False -
Interaction Score: 0.24
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Interaction Score: 0.15
Interaction Types & Directionality:
inhibitor (inhibitory) Interaction Info:
Details of the Assay for Interaction In a biochemical enzyme activity assay. Specific Action of the Ligand Inhibition Endogenous Drug? False -
Interaction Score: 0.05
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Interaction Score: 0.04
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Interaction Score: 0.03
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Interaction Score: 0.03
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Interaction Score: 0.02
-
Interaction Score: 0.02
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Interaction Score: 0.02
-
Interaction Score: 0.01
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- Version: 101_38
Alternate Names:
AXL Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 26-July-2011
Alternate Names:
ENSG00000167601 Ensembl Gene Id TYROSINE-PROTEIN KINASE RECEPTOR UFO PRECURSOR (EC 2.7.1.112) (AXL ONCOGENE). [SOURCE:UNIPROT/SWISSPROT;ACC:P30530] Description AXL Display Id Gene Info:
Human Readable Name DRUGGABLE GENOME Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
AXL Gene Symbol Gene Info:
Target Class Receptors Target Subclass EC:2.7.10.1 Publications:
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- Version: 11-September-2012
Alternate Names:
P30530 Uniprot Accession AXL Uniprot Gene Name UFO_HUMAN Uniprot Id Gene Info:
Uniprot Status Swiss-Prot Human Readable Name DRUGGABLE GENOME Interpro Acc IPR001245 Gene Categories:
KINASE, DRUGGABLE GENOME Publications:
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- Version: 29-September-2020
Alternate Names:
905 HUGO Gene ID 905 HUGO Gene Symbol AXL receptor tyrosine kinase HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family GuideToPharmacology Gene Category ID 328 Publications:
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Alternate Names:
AXL DrugBank Gene Name P30530 UniProt Accession 558 Entrez Gene Id Gene Info:
Publications:
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Alternate Names:
Gene Info:
Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000167601 Gene Symbol AXL Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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- Version: chembl_23
Alternate Names:
UFO GENE_SYMBOL AXL GENE_SYMBOL Tyrosine-protein kinase receptor UFO UNIPROT Gene Info:
Publications:
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- Version: 19.3
Alternate Names:
ENSG00000167601 Ensembl Gene ID ARK Human Protein Atlas Gene Synonym JTK11 Human Protein Atlas Gene Synonym Gene Info:
Gene Categories:
ENZYME Publications:
-
Alternate Names:
Tyrosine-protein kinase receptor UFO Gene Name P30530 UniProt ID Gene Info:
Gene Categories:
KINASE Publications:
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Alternate Names:
UFO GO Gene Synonym Gene Info:
Gene Categories:
CELL SURFACE, TYROSINE KINASE Publications:
-
Alternate Names:
AXL Gene Symbol Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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Alternate Names:
558 Gene ID JTK11 dGene Synonym UFO dGene Synonym Gene Info:
Gene Categories:
KINASE, TYROSINE KINASE Publications:
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- Version: 2020.06.01
Alternate Names:
AXL TTD Gene Abbreviation T82383 TTD Target ID Gene Info:
Publications:
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Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 03-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
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- Version: 04-September-2020
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications:
-
Alternate Names:
Gene Info:
Gene Categories:
CLINICALLY ACTIONABLE Publications: