558 |
AXL RECEPTOR TYROSINE KINASE |
AXL |
ARK |
JTK11 |
Tyro7 |
UFO |
109135 |
905 |
ENSG00000167601 |
OTTHUMG00000182727 |
AXL oncogene |
Tyrosine-protein kinase receptor UFO |
P30530 |
UFO_HUMAN |
TYROSINE-PROTEIN KINASE RECEPTOR UFO PRECURSOR (EC 2.7.1.112) (AXL ONCOGENE). [SOURCE:UNIPROT/SWISSPROT;ACC:P30530] |
1835 |
NP_001690 |
NM_001699 |
Tyrosine-protein kinase UFO |
T82383 |
BE0009412 |
Uniprot Status | Swiss-Prot |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR001245 |
Human Readable Name | KINASE |
Interpro Type | Domain |
Uniprot Evidence | 1: Evidence at protein level |
Interpro Name | Serine-threonine/tyrosine-protein kinase catalytic domain |
Interpro Short Name | Ser-Thr/Tyr_kinase_cat_dom |
GuideToPharmacology Gene Category Name | Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family |
GuideToPharmacology Gene Category ID | 328 |
Target Class | Receptors |
Target Subclass | EC:2.7.10.1 |
Gene Biotype | PROTEIN_CODING |
CELL SURFACE |
KINASE |
TYROSINE KINASE |
DRUGGABLE GENOME |
CLINICALLY ACTIONABLE |
ENZYME |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Direct Interaction | yes |
Mechanism of Interaction | Tyrosine-protein kinase receptor UFO inhibitor |
inhibitor (inhibitory) |
Direct Interaction? | False |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
inhibitor (inhibitory) |
Endogenous Drug? | False |
Specific Action of the Ligand | Inhibition |
Direct Interaction? | False |
inhibitor (inhibitory) |
Mechanism of Interaction | Tyrosine-protein kinase receptor UFO inhibitor |
Direct Interaction | yes |
inhibitor (inhibitory) |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
Direct Interaction? | False |
inhibitor (inhibitory) |
Details of the Assay for Interaction | Inhibition of <i>in vitro</i> biochemical activity by EMD Millipore assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
inhibitor (inhibitory) |
Details of the Assay for Interaction | In a biochemical enzyme activity assay. |
Specific Action of the Ligand | Inhibition |
Endogenous Drug? | False |
AXL | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ENSG00000167601 | Ensembl Gene Id |
TYROSINE-PROTEIN KINASE RECEPTOR UFO PRECURSOR (EC 2.7.1.112) (AXL ONCOGENE). [SOURCE:UNIPROT/SWISSPROT;ACC:P30530] | Description |
AXL | Display Id |
Human Readable Name | DRUGGABLE GENOME |
DRUGGABLE GENOME |
AXL | Gene Symbol |
Target Class | Receptors |
Target Subclass | EC:2.7.10.1 |
P30530 | Uniprot Accession |
AXL | Uniprot Gene Name |
UFO_HUMAN | Uniprot Id |
Uniprot Status | Swiss-Prot |
Human Readable Name | DRUGGABLE GENOME |
Interpro Acc | IPR001245 |
KINASE, DRUGGABLE GENOME |
905 | HUGO Gene ID |
905 | HUGO Gene Symbol |
AXL receptor tyrosine kinase | HUGO Gene Name |
GuideToPharmacology Gene Category Name | Type XI RTKs: TAM (TYRO3-, AXL- and MER-TK) receptor family |
GuideToPharmacology Gene Category ID | 328 |
AXL | DrugBank Gene Name |
P30530 | UniProt Accession |
558 | Entrez Gene Id |
ENSG00000167601 | Gene Symbol |
AXL | Ensembl Id |
DRUGGABLE GENOME |
UFO | GENE_SYMBOL |
AXL | GENE_SYMBOL |
Tyrosine-protein kinase receptor UFO | UNIPROT |
ENSG00000167601 | Ensembl Gene ID |
ARK | Human Protein Atlas Gene Synonym |
JTK11 | Human Protein Atlas Gene Synonym |
ENZYME |
Tyrosine-protein kinase receptor UFO | Gene Name |
P30530 | UniProt ID |
KINASE |
UFO | GO Gene Synonym |
CELL SURFACE, TYROSINE KINASE |
AXL | Gene Symbol |
CLINICALLY ACTIONABLE |
558 | Gene ID |
JTK11 | dGene Synonym |
UFO | dGene Synonym |
KINASE, TYROSINE KINASE |
AXL | TTD Gene Abbreviation |
T82383 | TTD Target ID |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |
CLINICALLY ACTIONABLE |