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ASL Gene Record

  • Summary
  • Interactions
  • Claims
  • ASL 435

    Alternate Names:

    435
    ARGININOSUCCINATE LYASE
    ASL
    ASAL
    608310
    746
    ENSG00000126522
    OTTHUMG00000022876
    PA25046
    BE0000520
    P04424

    Gene Info:

    Gene Biotype PROTEIN_CODING
    (0 More Sources)

    Gene Categories: Category Details

    ENZYME

    Publications:

    Moradi et al., 2006, Effect of chronic renal failure on arginase and argininosuccinate synthetase expression., Am. J. Nephrol.
    Tischner et al., 2007, Interference with the citrulline-based nitric oxide synthase assay by argininosuccinate lyase activity in Arabidopsis extracts., FEBS J.
    Mages et al., 2007, Complementation of the Chlamydomonas reinhardtii arg7-8 (arg2) point mutation by recombination with a truncated nonfunctional ARG7 gene., Protist
    Mori, 2007, Regulation of nitric oxide synthesis and apoptosis by arginase and arginine recycling., J. Nutr.
    Bizzoco et al., 2007, Transient ischemia increases neuronal nitric oxide synthase, argininosuccinate synthetase and argininosuccinate lyase co-expression in rat striatal neurons., Exp. Neurol.
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
  • ARGININE   ASL

    Interaction Score: 17.04

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    16809898 17651442 17611150 17513437 17198704


    Sources:
    DrugBank

  • CHEMBL1234276   ASL

    Interaction Score: 4.37

    Interaction Types & Directionality:
    n/a

    Interaction Info:

    PMIDs:
    10592235


    Sources:
    DrugBank

  • Ensembl: ENSG00000126522

    • Version: 101_38

    Alternate Names:
    ASL Ensembl Gene Name

    Gene Info:
    Gene Biotype PROTEIN_CODING

    Publications:

  • DrugBank: BE0000520

    • Version: 5.1.7

    Alternate Names:
    ASL DrugBank Gene Name
    P04424 UniProt Accession
    435 Entrez Gene Id

    Gene Info:

    Publications:
    Berman et al., 2000, The Protein Data Bank., Nucleic Acids Res.
    Overington et al., 2006, How many drug targets are there?, Nat Rev Drug Discov
    Imming et al., 2006, Drugs, their targets and the nature and number of drug targets., Nat Rev Drug Discov

  • PharmGKB: ASL

    • Version: 18-August-2020

    Alternate Names:
    PA25046 PharmGKB ID

    Gene Info:

    Publications:

  • HumanProteinAtlas: ASL

    • Version: 19.3

    Alternate Names:
    ENSG00000126522 Ensembl Gene ID
    Argininosuccinate lyase Human Protein Atlas Gene Description
    P04424 UniProt ID

    Gene Info:

    Gene Categories:
    ENZYME

    Publications:

Disclaimer: This resource is intended for purely research purposes. It should not be used for emergencies or medical or professional advice.

A finding of a drug-gene interaction or potentially druggable category does not necessarily indicate effectiveness (or lack thereof) of any drug or treatment regimen. A finding of no interaction or no potentially druggable category does not necessarily indicate lack of effectiveness of any drug or treatment regimen. Drug-gene interactions or potentially druggable categories are not presented in ranked order of potential or predicted efficacy.

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DGIdb (v4.2.0 - sha1 afd9f30b) • Last updated 2020-10-21