9311 |
ACID SENSING ION CHANNEL SUBUNIT 3 |
ASIC3 |
ACCN3 |
DRASIC |
SLNAC1 |
TNaC1 |
611741 |
101 |
ENSG00000213199 |
OTTHUMG00000158685 |
BE0004768 |
Q9UHC3 |
686 |
ASIC3_HUMAN |
ACID-SENSING ION CHANNEL 3 |
GuideToPharmacology Gene Category Name | Acid-sensing (proton-gated) ion channels (ASICs) |
GuideToPharmacology Gene Category ID | 118 |
Target Class | transporter |
Target Subclass | TC:1.A.6.1.2 |
Interpro Name | Na+ channel, amiloride-sensitive |
Human Readable Name | ION CHANNEL |
Interpro Acc | IPR001873 |
Human Readable Name | DRUGGABLE GENOME |
Interpro Type | Family |
Uniprot Evidence | 1: Evidence at protein level |
Uniprot Status | Swiss-Prot |
Interpro Short Name | Na+channel_ASC |
Gene Biotype | PROTEIN_CODING |
ION CHANNEL |
DRUGGABLE GENOME |
activator (activating) |
Endogenous Drug? | False |
Details of Interaction | at pH 7.4 |
Specific Action of the Ligand | None |
blocker (inhibitory) |
Details of the Assay for Interaction | Human ASIC3 expressed in HEK293 cells |
Specific Action of the Ligand | None |
Endogenous Drug? | False |
activator (activating) |
agonist (activating) |
Endogenous Drug? | False |
Details of Interaction | at pH 7.4 |
Specific Action of the Ligand | None |
blocker (inhibitory) |
Specific Action of the Ligand | None |
Endogenous Drug? | False |
Direct Interaction? | False |
blocker (inhibitory) |
Specific Action of the Ligand | None |
Details of Interaction | transient component |
Endogenous Drug? | False |
blocker (inhibitory) |
Endogenous Drug? | False |
Details of Interaction | transient component only - sustained component enhanced by 200μM amiloride at pH 4 |
Specific Action of the Ligand | None |
blocker (inhibitory) |
Specific Action of the Ligand | None |
Details of Interaction | sustained component |
Endogenous Drug? | False |
blocker (inhibitory) |
Endogenous Drug? | False |
Details of Interaction | sustained component |
Specific Action of the Ligand | None |
ASIC3 | Ensembl Gene Name |
Gene Biotype | PROTEIN_CODING |
ACID-SENSING ION CHANNEL 3 | Uniprot Protein Name |
ASIC3_HUMAN | Uniprot Id |
ENSG00000213199 | Ensembl Gene Id |
Interpro Name | Na+ channel, amiloride-sensitive |
Human Readable Name | ION CHANNEL |
Interpro Acc | IPR001873 |
ION CHANNEL, DRUGGABLE GENOME |
ACCN3 | Gene Symbol |
Target Class | transporter |
Target Subclass | TC:1.A.6.1.2 |
101 | HUGO Gene ID |
101 | HUGO Gene Symbol |
acid sensing ion channel subunit 3 | HUGO Gene Name |
GuideToPharmacology Gene Category Name | Acid-sensing (proton-gated) ion channels (ASICs) |
GuideToPharmacology Gene Category ID | 118 |
ION CHANNEL |
ASIC3 | DrugBank Gene Name |
Q9UHC3 | UniProt Accession |
9311 | Entrez Gene Id |
ENSG00000213199 | Gene Symbol |
ASIC3 | Ensembl Id |
DRUGGABLE GENOME |
Acid-sensing ion channel 3 | Gene Name |
Q9UHC3 | UniProt ID |
ION CHANNEL |