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ASIC3 9311 Druggable Genome
Alternate Names:
9311 ACID SENSING ION CHANNEL SUBUNIT 3 ASIC3 ACCN3 DRASIC SLNAC1 TNaC1 611741 101 ENSG00000213199 OTTHUMG00000158685 Q9UHC3 686 ASIC3_HUMAN ACID-SENSING ION CHANNEL 3 Gene Info:
GuideToPharmacology Gene Category Name Acid-sensing (proton-gated) ion channels (ASICs) GuideToPharmacology Gene Category ID 118 Target Class transporter Target Subclass TC:1.A.6.1.2 Interpro Name Na+ channel, amiloride-sensitive Human Readable Name ION CHANNEL Interpro Acc IPR001873 Human Readable Name DRUGGABLE GENOME Interpro Type Family Uniprot Evidence 1: Evidence at protein level Uniprot Status Swiss-Prot Interpro Short Name Na+channel_ASC Gene Biotype PROTEIN_CODING Gene Categories: Category Details
ION CHANNEL DRUGGABLE GENOME
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Interaction Types & Directionality:
activator (activating) agonist (activating) Interaction Info:
Endogenous Drug? False Details of Interaction at pH 7.4 Specific Action of the Ligand None -
Interaction Types & Directionality:
activator (activating) Interaction Info:
Endogenous Drug? False Details of Interaction at pH 7.4 Specific Action of the Ligand None -
Interaction Score: 3.99
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Details of the Assay for Interaction Human ASIC3 expressed in HEK293 cells Specific Action of the Ligand None Endogenous Drug? False -
Interaction Score: 2.66
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Specific Action of the Ligand None Endogenous Drug? False Direct Interaction? False -
Interaction Score: 0.72
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Specific Action of the Ligand None Details of Interaction transient component Endogenous Drug? False -
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Endogenous Drug? False Details of Interaction transient component only - sustained component enhanced by 200μM amiloride at pH 4 Specific Action of the Ligand None -
Interaction Score: 0.33
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Specific Action of the Ligand None Details of Interaction sustained component Endogenous Drug? False -
Interaction Types & Directionality:
blocker (inhibitory) Interaction Info:
Endogenous Drug? False Details of Interaction sustained component Specific Action of the Ligand None
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- Version: 101_38
Alternate Names:
ASIC3 Ensembl Gene Name Gene Info:
Gene Biotype PROTEIN_CODING Publications:
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- Version: 11-September-2012
Alternate Names:
ACID-SENSING ION CHANNEL 3 Uniprot Protein Name ASIC3_HUMAN Uniprot Id ENSG00000213199 Ensembl Gene Id Gene Info:
Interpro Name Na+ channel, amiloride-sensitive Human Readable Name ION CHANNEL Interpro Acc IPR001873 Gene Categories:
ION CHANNEL, DRUGGABLE GENOME Publications:
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- Version: January-2014
Alternate Names:
ACCN3 Gene Symbol Gene Info:
Target Class transporter Target Subclass TC:1.A.6.1.2 Publications:
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- Version: 29-September-2020
Alternate Names:
101 HUGO Gene ID 101 HUGO Gene Symbol acid sensing ion channel subunit 3 HUGO Gene Name Gene Info:
GuideToPharmacology Gene Category Name Acid-sensing (proton-gated) ion channels (ASICs) GuideToPharmacology Gene Category ID 118 Gene Categories:
ION CHANNEL Publications:
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- Version: 31-May-2017
Alternate Names:
ENSG00000213199 Gene Symbol ASIC3 Ensembl Id Gene Info:
Gene Categories:
DRUGGABLE GENOME Publications:
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Alternate Names:
Acid-sensing ion channel 3 Gene Name Q9UHC3 UniProt ID Gene Info:
Gene Categories:
ION CHANNEL Publications: